ParkinsonFranceV1, Main, Curation, bibRecord, 004E34

Relationship between levodopa-independent symptoms and central atrophy evaluated by magnetic resonance imaging in Parkinson's disease

Identifieur interne : 004E34 ( Main/Curation ); précédent : 004E33; suivant : 004E35

Relationship between levodopa-independent symptoms and central atrophy evaluated by magnetic resonance imaging in Parkinson's disease

Auteurs : F. Durif [France] ; P. Pollak [France] ; M. Hommel ; C. Ardouin ; J. F. Le Bas ; G. Crouzet ; J. Perret

Source :

European neurology [ 0014-3022 ] ; 1992.

RBID : Pascal:92-0160305

Descripteurs français

Pascal (Inist)
- Parkinson maladie, Maladie dégénérative, Atrophie, Encéphale, Imagerie RMN, Exploration, Noyau gris central, Trouble moteur, Trouble marche, Trouble équilibre, Homme, Système nerveux pathologie, Bradykinésie.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Aged, Atrophia, Atrophy, Basal ganglion, Brain (vertebrata), Degenerative disease, Equilibrium disorder, Exploration, Female, Frontal Lobe (pathology), Gait disorder, Human, Humans, Levodopa (therapeutic use), Magnetic Resonance Imaging, Male, Motor system disorder, Nervous system diseases, Neurologic Examination, Nuclear magnetic resonance imaging, Parkinson Disease (diagnosis), Parkinson Disease (drug therapy), Parkinson Disease (pathology), Parkinson disease.
MESH :
- chemical , therapeutic use : Levodopa.
- diagnosis : Parkinson Disease.
- drug therapy : Parkinson Disease.
- pathology : Frontal Lobe, Parkinson Disease.
- Aged, Atrophy, Female, Humans, Magnetic Resonance Imaging, Male, Neurologic Examination.

Abstract

Thirty patients with Parkinson's disease were studied for the purpose of investigation relations between motor symptoms and cerebral atrophy evaluated by magnetic resonance imaging (MRI). Axial symptoms (gait disorder, postural instability and difficulty in arising from a chair), assessed at the time of maximum clinical improvement, were significantly correlated with frontal atrophy, while no correlation was found between the basal parkinsonian disability score and cerebral atrophy. It is suggested that frontal atrophy observed by MRI is linked with axial motor symptoms resulting from non-dopaminergic lesions

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Pascal:92-0160305

Le document en format XML

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<author><name sortKey="Hommel, M" sort="Hommel, M" uniqKey="Hommel M" first="M" last="Hommel">M. Hommel</name>
</author>
<author><name sortKey="Ardouin, C" sort="Ardouin, C" uniqKey="Ardouin C" first="C" last="Ardouin">C. Ardouin</name>
</author>
<author><name sortKey="Le Bas, J F" sort="Le Bas, J F" uniqKey="Le Bas J" first="J F" last="Le Bas">J F Le Bas</name>
</author>
<author><name sortKey="Crouzet, G" sort="Crouzet, G" uniqKey="Crouzet G" first="G" last="Crouzet">G. Crouzet</name>
</author>
<author><name sortKey="Perret, J" sort="Perret, J" uniqKey="Perret J" first="J" last="Perret">J. Perret</name>
</author>
</analytic>
<series><title level="j">European neurology</title>
<idno type="ISSN">0014-3022</idno>
<imprint><date when="1992" type="published">1992</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Atrophy</term>
<term>Female</term>
<term>Frontal Lobe (pathology)</term>
<term>Humans</term>
<term>Levodopa (therapeutic use)</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Neurologic Examination</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (pathology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Levodopa</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Frontal Lobe</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Atrophy</term>
<term>Female</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Neurologic Examination</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Thirty patients with Parkinson's disease were studied for the purpose of investigation relations between motor symptoms and cerebral atrophy evaluated by magnetic resonance imaging (MRI). Axial symptoms (gait disorder, postural instability and difficulty in arising from a chair), assessed at the time of maximum clinical improvement, were significantly correlated with frontal atrophy, while no correlation was found between the basal parkinsonian disability score and cerebral atrophy. It is suggested that frontal atrophy observed by MRI is linked with axial motor symptoms resulting from non-dopaminergic lesions. The origin of this atrophy is unknown.</div>
</front>
</TEI>
</PubMed>
</double>
</record>

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	La maladie de Parkinson en France (serveur d'exploration)
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La maladie de Parkinson en France (serveur d'exploration)

Relationship between levodopa-independent symptoms and central atrophy evaluated by magnetic resonance imaging in Parkinson's disease

Relationship between levodopa-independent symptoms and central atrophy evaluated by magnetic resonance imaging in Parkinson's disease

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