Apomorphine increases blood glucose concentrations in Parkinson's disease
Identifieur interne : 004A92 ( Main/Curation ); précédent : 004A91; suivant : 004A93Apomorphine increases blood glucose concentrations in Parkinson's disease
Auteurs : F. Tison [France] ; N. Fouillet ; P. HenrySource :
- Clinical neuropharmacology [ 0362-5664 ] ; 1994.
Descripteurs français
- Pascal (Inist)
- Wicri :
English descriptors
- KwdEn :
- Aged, Apomorphine (adverse effects), Apomorphine (therapeutic use), Blood Glucose (metabolism), Carbohydrate, Dopamine agonist, Glucose, Human, Humans, Levodopa (therapeutic use), Parkinson Disease (blood), Parkinson Disease (drug therapy), Parkinson Disease, Secondary (drug therapy), Parkinson disease, Subcutaneous administration.
- MESH :
- chemical , adverse effects : Apomorphine.
- chemical , metabolism : Blood Glucose.
- chemical , therapeutic use : Apomorphine, Levodopa.
- blood : Parkinson Disease.
- drug therapy : Parkinson Disease, Parkinson Disease, Secondary.
- Aged, Humans.
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Pascal:94-0257650Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Apomorphine increases blood glucose concentrations in Parkinson's disease.</title>
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<author><name sortKey="Fouillet, N" sort="Fouillet, N" uniqKey="Fouillet N" first="N" last="Fouillet">N. Fouillet</name>
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<term>Blood Glucose (metabolism)</term>
<term>Humans</term>
<term>Levodopa (therapeutic use)</term>
<term>Parkinson Disease (blood)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease, Secondary (drug therapy)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Apomorphine</term>
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</keywords>
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<term>Levodopa</term>
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<front><div type="abstract" xml:lang="en">Data from studies indicate that blood glucose levels may be influenced by stimulation of central D1 and D2 dopamine receptors. This is modulated by central dopamine receptor status. We studied apomorphine-induced increase in blood glucose levels in Parkinson's disease compared with those in Parkinsonian syndromes unresponsive to dopaminergic drugs. Results indicate that apomorphine-induced blood glucose level increases are significant only in Parkinson's disease. As in the animal, this could possibly be explained by central dopamine receptor status.</div>
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