ParkinsonFranceV1, Main, Curation, bibRecord, 003B95

Effect of bilateral deep-brain stimulation on oral control of patients with parkinsonism

Identifieur interne : 003B95 ( Main/Curation ); précédent : 003B94; suivant : 003B96

Effect of bilateral deep-brain stimulation on oral control of patients with parkinsonism

Auteurs : Michèle Gentil [France] ; Pedro Garcia-Ruiz [Espagne] ; Pierre Pollak [France] ; Alim-Louis Benabid [France]

Source :

European neurology [ 0014-3022 ] ; 2000.

RBID : Pascal:00-0478447

Descripteurs français

Pascal (Inist)
- Parkinson maladie, Dysarthrie, Stimulus électrique, Bilatéral, Thalamus, Noyau sousthalamique, Lèvre, Langue, Contrôle moteur, Parole, Traitement instrumental, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Adult, Aged, Articulation Disorders (physiopathology), Articulation Disorders (therapy), Bilateral, Bite Force, Brain Mapping, Dominance, Cerebral (physiology), Dysarthria, Electric Stimulation Therapy (instrumentation), Electrical stimulus, Electrodes, Implanted, Female, Human, Humans, Instrumentation therapy, Lip, Male, Middle Aged, Motor Neurons (physiology), Motor control, Neurons (physiology), Parkinson Disease (physiopathology), Parkinson Disease (therapy), Parkinson disease, Speech, Speech Articulation Tests, Subthalamic Nucleus (physiopathology), Subthalamic nucleus, Thalamus, Tongue, Ventral Thalamic Nuclei (physiopathology).
MESH :
- instrumentation : Electric Stimulation Therapy.
- physiology : Dominance, Cerebral, Motor Neurons, Neurons.
- physiopathology : Articulation Disorders, Parkinson Disease, Subthalamic Nucleus, Ventral Thalamic Nuclei.
- therapy : Articulation Disorders, Parkinson Disease.
- Adult, Aged, Bite Force, Brain Mapping, Electrodes, Implanted, Female, Humans, Male, Middle Aged, Speech Articulation Tests.

Abstract

We assessed the oral system of parkinsonian patients treated with bilateral chronic stimulation of the ventral intermediate nucleus of the thalamus (Vim), and of the subthalamic nucleus (STN) to compare the effects of these procedures on the articulatory organs. Force transducers were used to sample ramp-and-hold force contractions generated by the upper lip, lower lip and tongue at 1- and 2-newton target force levels, as well as maximal force. Fourteen healthy control subjects and 14 parkinsonian patients participated in this study. After an overnight fast the patients were evaluated under two conditions: during bilateral stimulation and 1 h after stopping stimulation. With Vim stimulation, dynamic and static control of the articulatory organs was worsened while with STN stimulation it was greatly improved. The target of stimulation differently influences the oral system and modulates neuronal structures involved in speech.

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Le document en format XML

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<front><div type="abstract" xml:lang="en">We assessed the oral system of parkinsonian patients treated with bilateral chronic stimulation of the ventral intermediate nucleus of the thalamus (Vim), and of the subthalamic nucleus (STN) to compare the effects of these procedures on the articulatory organs. Force transducers were used to sample ramp-and-hold force contractions generated by the upper lip, lower lip and tongue at 1- and 2-newton target force levels, as well as maximal force. Fourteen healthy control subjects and 14 parkinsonian patients participated in this study. After an overnight fast the patients were evaluated under two conditions: during bilateral stimulation and 1 h after stopping stimulation. With Vim stimulation, dynamic and static control of the articulatory organs was worsened while with STN stimulation it was greatly improved. The target of stimulation differently influences the oral system and modulates neuronal structures involved in speech.</div>
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<author><name sortKey="Garcia Ruiz, P" sort="Garcia Ruiz, P" uniqKey="Garcia Ruiz P" first="P" last="Garcia-Ruiz">P. Garcia-Ruiz</name>
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<author><name sortKey="Pollak, P" sort="Pollak, P" uniqKey="Pollak P" first="P" last="Pollak">P. Pollak</name>
</author>
<author><name sortKey="Benabid, A L" sort="Benabid, A L" uniqKey="Benabid A" first="A L" last="Benabid">A L Benabid</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Effect of bilateral deep-brain stimulation on oral control of patients with parkinsonism.</title>
<author><name sortKey="Gentil, M" sort="Gentil, M" uniqKey="Gentil M" first="M" last="Gentil">M. Gentil</name>
<affiliation wicri:level="1"><nlm:affiliation>INSERM Unit 318, CHU Grenoble, France. Michele.Gentil@ujf-grenoble.fr</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM Unit 318, CHU Grenoble</wicri:regionArea>
<wicri:noRegion>CHU Grenoble</wicri:noRegion>
<wicri:noRegion>CHU Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Garcia Ruiz, P" sort="Garcia Ruiz, P" uniqKey="Garcia Ruiz P" first="P" last="Garcia-Ruiz">P. Garcia-Ruiz</name>
</author>
<author><name sortKey="Pollak, P" sort="Pollak, P" uniqKey="Pollak P" first="P" last="Pollak">P. Pollak</name>
</author>
<author><name sortKey="Benabid, A L" sort="Benabid, A L" uniqKey="Benabid A" first="A L" last="Benabid">A L Benabid</name>
</author>
</analytic>
<series><title level="j">European neurology</title>
<idno type="ISSN">0014-3022</idno>
<imprint><date when="2000" type="published">2000</date>
</imprint>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Articulation Disorders (physiopathology)</term>
<term>Articulation Disorders (therapy)</term>
<term>Bite Force</term>
<term>Brain Mapping</term>
<term>Dominance, Cerebral (physiology)</term>
<term>Electric Stimulation Therapy (instrumentation)</term>
<term>Electrodes, Implanted</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Motor Neurons (physiology)</term>
<term>Neurons (physiology)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (therapy)</term>
<term>Speech Articulation Tests</term>
<term>Subthalamic Nucleus (physiopathology)</term>
<term>Ventral Thalamic Nuclei (physiopathology)</term>
</keywords>
<keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Electric Stimulation Therapy</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Dominance, Cerebral</term>
<term>Motor Neurons</term>
<term>Neurons</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Articulation Disorders</term>
<term>Parkinson Disease</term>
<term>Subthalamic Nucleus</term>
<term>Ventral Thalamic Nuclei</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Articulation Disorders</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Bite Force</term>
<term>Brain Mapping</term>
<term>Electrodes, Implanted</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Speech Articulation Tests</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We assessed the oral system of parkinsonian patients treated with bilateral chronic stimulation of the ventral intermediate nucleus of the thalamus (Vim), and of the subthalamic nucleus (STN) to compare the effects of these procedures on the articulatory organs. Force transducers were used to sample ramp-and-hold force contractions generated by the upper lip, lower lip and tongue at 1- and 2-newton target force levels, as well as maximal force. Fourteen healthy control subjects and 14 parkinsonian patients participated in this study. After an overnight fast the patients were evaluated under two conditions: during bilateral stimulation and 1 h after stopping stimulation. With Vim stimulation, dynamic and static control of the articulatory organs was worsened while with STN stimulation it was greatly improved. The target of stimulation differently influences the oral system and modulates neuronal structures involved in speech.</div>
</front>
</TEI>
</PubMed>
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	La maladie de Parkinson en France (serveur d'exploration)
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La maladie de Parkinson en France (serveur d'exploration)

Effect of bilateral deep-brain stimulation on oral control of patients with parkinsonism

Effect of bilateral deep-brain stimulation on oral control of patients with parkinsonism

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