Quantification of motor slowness in Parkinson's disease: Correlations between the tapping test and single joint ballistic movement parameters
Identifieur interne : 000497 ( Istex/Corpus ); précédent : 000496; suivant : 000498Quantification of motor slowness in Parkinson's disease: Correlations between the tapping test and single joint ballistic movement parameters
Auteurs : Thomas Boraud ; François Tison ; Christian GrossSource :
- Parkinsonism and Related Disorders [ 1353-8020 ] ; 1997.
Abstract
The tapping test is used routinely for the quantification of drug effects on motor slowness in Parkinson's disease (FD). This test has not been validated previously using reference methods measuring kinematic parameters of movement. We compared and correlated modifications of the tapping score induced by levodopa with that of kinematic parameters of a single joint ballistic movement in 10 PD patients. Results demonstrate that the modification of the tapping score correlates with the bradykinetic, but not the akinetic, component of motor slowness in PD. Also analyzed are the sensitivity and specificity of different thresholds of the increment of the tapping score for the detection of modifications in amplitude, velocity and acceleration. Using a tapping score threshold of positivity between 10 and 20% of increase, the sensitivity and specificity to detect significant modifications in velocity is 100%.
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DOI: 10.1016/S1353-8020(96)00039-9
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This test has not been validated previously using reference methods measuring kinematic parameters of movement. We compared and correlated modifications of the tapping score induced by levodopa with that of kinematic parameters of a single joint ballistic movement in 10 PD patients. Results demonstrate that the modification of the tapping score correlates with the bradykinetic, but not the akinetic, component of motor slowness in PD. Also analyzed are the sensitivity and specificity of different thresholds of the increment of the tapping score for the detection of modifications in amplitude, velocity and acceleration. Using a tapping score threshold of positivity between 10 and 20% of increase, the sensitivity and specificity to detect significant modifications in velocity is 100%.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>Thomas Boraud</name><affiliations><json:string>Groupe Motricité, Laboratoire de Neurophysiologie, CNRS UMR 5543, Université de Bordeaux II, Bordeaux, France</json:string></affiliations></json:item><json:item><name>François Tison</name><affiliations><json:string>Département de Neurologie, Hôpital Pellegrin, Bordeaux, France</json:string></affiliations></json:item><json:item><name>Christian Gross</name><affiliations><json:string>Groupe Motricité, Laboratoire de Neurophysiologie, CNRS UMR 5543, Université de Bordeaux II, Bordeaux, France</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Akinesia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>bradykinesia</value></json:item></subject><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>The tapping test is used routinely for the quantification of drug effects on motor slowness in Parkinson's disease (FD). This test has not been validated previously using reference methods measuring kinematic parameters of movement. We compared and correlated modifications of the tapping score induced by levodopa with that of kinematic parameters of a single joint ballistic movement in 10 PD patients. Results demonstrate that the modification of the tapping score correlates with the bradykinetic, but not the akinetic, component of motor slowness in PD. Also analyzed are the sensitivity and specificity of different thresholds of the increment of the tapping score for the detection of modifications in amplitude, velocity and acceleration. Using a tapping score threshold of positivity between 10 and 20% of increase, the sensitivity and specificity to detect significant modifications in velocity is 100%.</abstract><qualityIndicators><score>3.65</score><pdfVersion>1.2</pdfVersion><pdfPageSize>598 x 806 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>3</keywordCount><abstractCharCount>913</abstractCharCount><pdfWordCount>2018</pdfWordCount><pdfCharCount>13053</pdfCharCount><pdfPageCount>4</pdfPageCount><abstractWordCount>136</abstractWordCount></qualityIndicators><title>Quantification of motor slowness in Parkinson's disease: Correlations between the tapping test and single joint ballistic movement parameters</title><pii><json:string>S1353-8020(96)00039-9</json:string></pii><refBibs><json:item><author><json:item><name>C.D. 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Albani</name></json:item></author><host><volume>3</volume><pages><last>258</last><first>257</first></pages><author></author><title>New Trends Clin. Neuropharmacol.</title></host><title>Accuracy of tracking and tapping test in assessing effects of l-DOPA in Parkinsonian patients (abstract)</title></json:item></refBibs><genre><json:string>research-article</json:string></genre><host><volume>3</volume><pii><json:string>S1353-8020(00)X0007-7</json:string></pii><pages><last>50</last><first>47</first></pages><issn><json:string>1353-8020</json:string></issn><issue>1</issue><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><title>Parkinsonism and Related Disorders</title><publicationDate>1997</publicationDate></host><categories><wos><json:string>science</json:string><json:string>clinical neurology</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>neurology & neurosurgery</json:string></scienceMetrix></categories><publicationDate>1997</publicationDate><copyrightDate>1997</copyrightDate><doi><json:string>10.1016/S1353-8020(96)00039-9</json:string></doi><id>EFCC4E206F4739F24833F583295A3D28EA589D4D</id><score>0.28568995</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/EFCC4E206F4739F24833F583295A3D28EA589D4D/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/EFCC4E206F4739F24833F583295A3D28EA589D4D/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/EFCC4E206F4739F24833F583295A3D28EA589D4D/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a">Quantification of motor slowness in Parkinson's disease: Correlations between the tapping test and single joint ballistic movement parameters</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>1997</date></publicationStmt><notesStmt><note type="content">Section title: Paper</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Quantification of motor slowness in Parkinson's disease: Correlations between the tapping test and single joint ballistic movement parameters</title><author xml:id="author-1"><persName><forename type="first">Thomas</forename><surname>Boraud</surname></persName><affiliation>Address correspondence to: T. Boraud, Laboratoire de Neurophysiologie, CNRS UMR 5543, Université de Bordeaux II, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France. Tel: (33) 557 57 15 51; Fax: (33) 556 90 14 21.</affiliation><affiliation>Groupe Motricité, Laboratoire de Neurophysiologie, CNRS UMR 5543, Université de Bordeaux II, Bordeaux, France</affiliation></author><author xml:id="author-2"><persName><forename type="first">François</forename><surname>Tison</surname></persName><affiliation>Département de Neurologie, Hôpital Pellegrin, Bordeaux, France</affiliation></author><author xml:id="author-3"><persName><forename type="first">Christian</forename><surname>Gross</surname></persName><affiliation>Groupe Motricité, Laboratoire de Neurophysiologie, CNRS UMR 5543, Université de Bordeaux II, Bordeaux, France</affiliation></author></analytic><monogr><title level="j">Parkinsonism and Related Disorders</title><title level="j" type="abbrev">PRD</title><idno type="pISSN">1353-8020</idno><idno type="PII">S1353-8020(00)X0007-7</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1997"></date><biblScope unit="volume">3</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="47">47</biblScope><biblScope unit="page" to="50">50</biblScope></imprint></monogr><idno type="istex">EFCC4E206F4739F24833F583295A3D28EA589D4D</idno><idno type="DOI">10.1016/S1353-8020(96)00039-9</idno><idno type="PII">S1353-8020(96)00039-9</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1997</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The tapping test is used routinely for the quantification of drug effects on motor slowness in Parkinson's disease (FD). This test has not been validated previously using reference methods measuring kinematic parameters of movement. We compared and correlated modifications of the tapping score induced by levodopa with that of kinematic parameters of a single joint ballistic movement in 10 PD patients. Results demonstrate that the modification of the tapping score correlates with the bradykinetic, but not the akinetic, component of motor slowness in PD. Also analyzed are the sensitivity and specificity of different thresholds of the increment of the tapping score for the detection of modifications in amplitude, velocity and acceleration. Using a tapping score threshold of positivity between 10 and 20% of increase, the sensitivity and specificity to detect significant modifications in velocity is 100%.</p></abstract><textClass><keywords scheme="keyword"><list><head>Keywords</head><item><term>Parkinson's disease</term></item><item><term>Akinesia</term></item><item><term>bradykinesia</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1997">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/EFCC4E206F4739F24833F583295A3D28EA589D4D/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>PRD</jid><aid>96000399</aid><ce:pii>S1353-8020(96)00039-9</ce:pii><ce:doi>10.1016/S1353-8020(96)00039-9</ce:doi><ce:copyright type="unknown" year="1997"></ce:copyright></item-info><head><ce:dochead><ce:textfn>Paper</ce:textfn></ce:dochead><ce:title>Quantification of motor slowness in Parkinson's disease: Correlations between the tapping test and single joint ballistic movement parameters</ce:title><ce:author-group><ce:author><ce:given-name>Thomas</ce:given-name><ce:surname>Boraud</ce:surname><ce:cross-ref refid="COR1"><ce:sup>∗</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF1"><ce:sup>†</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>François</ce:given-name><ce:surname>Tison</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>‡</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Christian</ce:given-name><ce:surname>Gross</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>†</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>a</ce:label><ce:textfn>Groupe Motricité, Laboratoire de Neurophysiologie, CNRS UMR 5543, Université de Bordeaux II, Bordeaux, France</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>b</ce:label><ce:textfn>Département de Neurologie, Hôpital Pellegrin, Bordeaux, France</ce:textfn></ce:affiliation><ce:correspondence id="COR1"><ce:label>∗</ce:label><ce:text>Address correspondence to: T. Boraud, Laboratoire de Neurophysiologie, CNRS UMR 5543, Université de Bordeaux II, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France. Tel: (33) 557 57 15 51; Fax: (33) 556 90 14 21.</ce:text></ce:correspondence></ce:author-group><ce:date-received day="6" month="9" year="1996"></ce:date-received><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>The tapping test is used routinely for the quantification of drug effects on motor slowness in Parkinson's disease (FD). This test has not been validated previously using reference methods measuring kinematic parameters of movement. We compared and correlated modifications of the tapping score induced by levodopa with that of kinematic parameters of a single joint ballistic movement in 10 PD patients. Results demonstrate that the modification of the tapping score correlates with the bradykinetic, but not the akinetic, component of motor slowness in PD. Also analyzed are the sensitivity and specificity of different thresholds of the increment of the tapping score for the detection of modifications in amplitude, velocity and acceleration. Using a tapping score threshold of positivity between 10 and 20% of increase, the sensitivity and specificity to detect significant modifications in velocity is 100%.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:keywords><ce:section-title>Keywords</ce:section-title><ce:keyword><ce:text>Parkinson's disease</ce:text></ce:keyword><ce:keyword><ce:text>Akinesia</ce:text></ce:keyword><ce:keyword><ce:text>bradykinesia</ce:text></ce:keyword></ce:keywords></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Quantification of motor slowness in Parkinson's disease: Correlations between the tapping test and single joint ballistic movement parameters</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Quantification of motor slowness in Parkinson's disease: Correlations between the tapping test and single joint ballistic movement parameters</title></titleInfo><name type="personal"><namePart type="given">Thomas</namePart><namePart type="family">Boraud</namePart><affiliation>Groupe Motricité, Laboratoire de Neurophysiologie, CNRS UMR 5543, Université de Bordeaux II, Bordeaux, France</affiliation><description>Address correspondence to: T. Boraud, Laboratoire de Neurophysiologie, CNRS UMR 5543, Université de Bordeaux II, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France. Tel: (33) 557 57 15 51; Fax: (33) 556 90 14 21.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">François</namePart><namePart type="family">Tison</namePart><affiliation>Département de Neurologie, Hôpital Pellegrin, Bordeaux, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Christian</namePart><namePart type="family">Gross</namePart><affiliation>Groupe Motricité, Laboratoire de Neurophysiologie, CNRS UMR 5543, Université de Bordeaux II, Bordeaux, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1997</dateIssued><copyrightDate encoding="w3cdtf">1997</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">The tapping test is used routinely for the quantification of drug effects on motor slowness in Parkinson's disease (FD). This test has not been validated previously using reference methods measuring kinematic parameters of movement. We compared and correlated modifications of the tapping score induced by levodopa with that of kinematic parameters of a single joint ballistic movement in 10 PD patients. Results demonstrate that the modification of the tapping score correlates with the bradykinetic, but not the akinetic, component of motor slowness in PD. Also analyzed are the sensitivity and specificity of different thresholds of the increment of the tapping score for the detection of modifications in amplitude, velocity and acceleration. Using a tapping score threshold of positivity between 10 and 20% of increase, the sensitivity and specificity to detect significant modifications in velocity is 100%.</abstract><note type="content">Section title: Paper</note><subject><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>Akinesia</topic><topic>bradykinesia</topic></subject><relatedItem type="host"><titleInfo><title>Parkinsonism and Related Disorders</title></titleInfo><titleInfo type="abbreviated"><title>PRD</title></titleInfo><genre type="journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">199701</dateIssued></originInfo><identifier type="ISSN">1353-8020</identifier><identifier type="PII">S1353-8020(00)X0007-7</identifier><part><date>199701</date><detail type="volume"><number>3</number><caption>vol.</caption></detail><detail type="issue"><number>1</number><caption>no.</caption></detail><extent unit="issue pages"><start>1</start><end>63</end></extent><extent unit="pages"><start>47</start><end>50</end></extent></part></relatedItem><identifier type="istex">EFCC4E206F4739F24833F583295A3D28EA589D4D</identifier><identifier type="DOI">10.1016/S1353-8020(96)00039-9</identifier><identifier type="PII">S1353-8020(96)00039-9</identifier><recordInfo><recordContentSource>ELSEVIER</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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