La maladie de Parkinson au Canada (serveur d'exploration) - Curation (Istex)

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1709were
1388these
959results
931but
862study
838may
831than
813also
785both
780disease
651other
641effects
637patients
617parkinson
615all
563after
561during
551high
543had
532significant
525data
524increased
522however
522associated
514effect
493studies
490there
490found
486observed
479compared
477only
476treatment
474present
468significantly
467most
466well
464analysis
453suggest
447three
447different
443control
438brain
436activity
432when
427changes
419levels
418time
416related
413induced
391showed
389cells
380over
376within
376system
367clinical
362those
360following
359normal
356increase
354first
354did
347cell
344evidence
343similar
341model
332while
332higher
327age
325dopamine
324role
321low
317specific
310potential
309response
309although
308each
305abstract
304including
303human
301measured
301important
300wiley
300function
299years
295new
291lower
290conditions
288rate
287studied
286findings
284examined
284either
278neurons
277number
276level
276could
275disorder
275development
272several
272reduced
270rat
268concentrations
266movement
264early
262large
260type
259non
259further
258addition
257total
257inc
256same
256investigated
256due
255long
255group
254protein
253through
251reported
250respectively
249species
249rats
247indicate
245under
245determined
244range
244four
241treated
241loss
240motor
239presence
239period
239obtained
238groups
237receptor
237factors
235show
233less
232greater
232differences
231thus
230decreased
229mean
228shown
228region
228major
227possible
225society
225growth
224whereas
222gene
222change
221whether
221many
220review
219canada
218discussed
217without
217concentration
215dependent
215binding
213liss
212relative
212determine
210provide
210previously
210acid
208developed
207animals
205who
205expression
204various
204identified
203small
203sites
203known
202subjects
201because
200performed
198test
198term
198research
198rates
198demonstrated
196regions
196methods
196drug
196days
195neuronal
195any
194therapy
194produced
194patient
193values
193controls
192models
190single
190result
190mechanisms
190dopaminergic
188functional
188cases
187consistent
186common
186case
185revealed
184surface
184should
184previous
183factor
183central
182where
182involved
182field
181striatum
181distribution
181contrast
180properties
178systems
178made
177dose
176tested
176second
176receptors
176population
175water
175method
174processes
174complex
174administration
173positive
173formation
172year
171recent
171increasing
169nucleus
169multiple
169decrease
169activation
168support
168stimulation
168cortex
168caused
168assessed
167presented
167given
167experimental
166least
165primary
165part
165information
164suggests
164likely
163site
163free
163disorders
163area
162performance
162paper
161pattern
161day
160syndrome
160symptoms
160order
160current
159striatal
159scale
159risk
159process
159before
158relationship
157will
156structure
156soil
156ratio
156production
156indicated
154since
153very
153tissue
153suggesting
153described
152influence
152experiments
152characterized
151features
151effective
151affected
150activities
149types
149content
148then
148suggested
148mediated
148five
148blood
148approach
147occurred
147form
147characteristics
146report
145six
145implications
145cause
145against
144state
144pathway
144parkinsonism
144mechanism
144induction
144derived
144adult
143would
143therefore
143followed
143body
142techniques
142evaluated
142being
142ability
141substantia
141nigra
141comparison
140responses
140reduction
140patterns
140difference
139samples
139observations
139individual
139exposure
139considered
139areas
138much
137months
137even
137assess
136vitro
136molecular
136measurements
136highly
136basal
136available
134life
133phase
133increases
132temperature
132seen
132out
132like
132inhibition
132energy
132density
131here
131enzyme
130produce
129variation
129selective
129resulted
129genetic
129general
129containing
128times
128rapid
128overall
128direct
128chronic
127understanding
127recently
126size
126required
126frequency
126correlation
125proteins
125proposed
125left
125included
125correlated
125basis
124short
124ice
124hypothesis
124assessment
123value
122sea
122initial
122analyses
121relatively
121per
121novel
121flow
121distinct
121appears
120structures
120duration
119work
119weeks
119often
119methyl
119does
119death
118negative
117release
117populations
117particularly
117onset
117lesions
117extent
117enhanced
117detected
117combined
117action
116post
116occur
116laboratory
116genes
116alzheimer
115weight
115vivo
115series
115right
115provides
115emission
115cortical
115canadian
115applied
114survival
114damage
114cognitive
114along
113uptake
113pathways
113include
112white
112upon
112technique
112severe
112might
112application
112across
111useful
111rather
111future
111behavior
111association
110structural
110sensitive
110metabolism
110mass
110individuals
110evaluation
110component
110active
109hydroxylase
109demonstrate
109above
108levodopa
107parameters
107investigate
107established
106treatments
106testing
106progressive
106nervous
106interaction
106end
106arctic
105ventricular
105line
105independent
105few
105combination
105approximately
104task
104source
104play
104interactions
104drugs
104animal
103summary
103lateral
103late
103despite
103controlled
102received
102male
102improved
102functions
102dementia
102components
101via
101probably
101matched
101average
101alone
100mice
100measure
100good
100cerebral
100absence

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