Age-specific mortality during the 1918 influenza pandemic: unravelling the mystery of high young adult mortality.
Identifieur interne : 000969 ( PubMed/Curation ); précédent : 000968; suivant : 000970Age-specific mortality during the 1918 influenza pandemic: unravelling the mystery of high young adult mortality.
Auteurs : Alain Gagnon [Canada] ; Matthew S. Miller ; Stacey A. Hallman ; Robert Bourbeau ; D Ann Herring ; David J D. Earn ; Joaquín MadrenasSource :
- PloS one [ 1932-6203 ] ; 2013.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Canada (épidémiologie), Enfant, Enfant d'âge préscolaire, Femelle, Grippe humaine (mortalité), Grippe humaine (épidémiologie), Humains, Jeune adulte, Mâle, Nourrisson, Nouveau-né, Pandémies (), Répartition par âge, Sujet âgé, Sujet âgé de 80 ans ou plus, États-Unis d'Amérique (épidémiologie).
- MESH :
- mortalité : Grippe humaine.
- épidémiologie : Canada, Grippe humaine, États-Unis d'Amérique.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Jeune adulte, Mâle, Nourrisson, Nouveau-né, Pandémies, Répartition par âge, Sujet âgé, Sujet âgé de 80 ans ou plus.
- Wicri :
- geographic : Canada, États-Unis.
English descriptors
- KwdEn :
- Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Canada (epidemiology), Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Influenza, Human (epidemiology), Influenza, Human (mortality), Male, Middle Aged, Pandemics (statistics & numerical data), United States (epidemiology), Young Adult.
- MESH :
- geographic , epidemiology : Canada, United States.
- epidemiology : Influenza, Human.
- mortality : Influenza, Human.
- statistics & numerical data : Pandemics.
- Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Young Adult.
Abstract
The worldwide spread of a novel influenza A (H1N1) virus in 2009 showed that influenza remains a significant health threat, even for individuals in the prime of life. This paper focuses on the unusually high young adult mortality observed during the Spanish flu pandemic of 1918. Using historical records from Canada and the U.S., we report a peak of mortality at the exact age of 28 during the pandemic and argue that this increased mortality resulted from an early life exposure to influenza during the previous Russian flu pandemic of 1889-90. We posit that in specific instances, development of immunological memory to an influenza virus strain in early life may lead to a dysregulated immune response to antigenically novel strains encountered in later life, thereby increasing the risk of death. Exposure during critical periods of development could also create holes in the T cell repertoire and impair fetal maturation in general, thereby increasing mortality from infectious diseases later in life. Knowledge of the age-pattern of susceptibility to mortality from influenza could improve crisis management during future influenza pandemics.
DOI: 10.1371/journal.pone.0069586
PubMed: 23940526
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000969
Links to Exploration step
pubmed:23940526Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Age-specific mortality during the 1918 influenza pandemic: unravelling the mystery of high young adult mortality.</title>
<author><name sortKey="Gagnon, Alain" sort="Gagnon, Alain" uniqKey="Gagnon A" first="Alain" last="Gagnon">Alain Gagnon</name>
<affiliation wicri:level="1"><nlm:affiliation>Département de Démographie, Université de Montréal, Montreal, Quebec, Canada. alain.gagnon.4@umontreal.ca</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Département de Démographie, Université de Montréal, Montreal, Quebec</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Miller, Matthew S" sort="Miller, Matthew S" uniqKey="Miller M" first="Matthew S" last="Miller">Matthew S. Miller</name>
</author>
<author><name sortKey="Hallman, Stacey A" sort="Hallman, Stacey A" uniqKey="Hallman S" first="Stacey A" last="Hallman">Stacey A. Hallman</name>
</author>
<author><name sortKey="Bourbeau, Robert" sort="Bourbeau, Robert" uniqKey="Bourbeau R" first="Robert" last="Bourbeau">Robert Bourbeau</name>
</author>
<author><name sortKey="Herring, D Ann" sort="Herring, D Ann" uniqKey="Herring D" first="D Ann" last="Herring">D Ann Herring</name>
</author>
<author><name sortKey="Earn, David J D" sort="Earn, David J D" uniqKey="Earn D" first="David J D" last="Earn">David J D. Earn</name>
</author>
<author><name sortKey="Madrenas, Joaquin" sort="Madrenas, Joaquin" uniqKey="Madrenas J" first="Joaquín" last="Madrenas">Joaquín Madrenas</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2013">2013</date>
<idno type="RBID">pubmed:23940526</idno>
<idno type="pmid">23940526</idno>
<idno type="doi">10.1371/journal.pone.0069586</idno>
<idno type="wicri:Area/PubMed/Corpus">000969</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000969</idno>
<idno type="wicri:Area/PubMed/Curation">000969</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000969</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Age-specific mortality during the 1918 influenza pandemic: unravelling the mystery of high young adult mortality.</title>
<author><name sortKey="Gagnon, Alain" sort="Gagnon, Alain" uniqKey="Gagnon A" first="Alain" last="Gagnon">Alain Gagnon</name>
<affiliation wicri:level="1"><nlm:affiliation>Département de Démographie, Université de Montréal, Montreal, Quebec, Canada. alain.gagnon.4@umontreal.ca</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Département de Démographie, Université de Montréal, Montreal, Quebec</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Miller, Matthew S" sort="Miller, Matthew S" uniqKey="Miller M" first="Matthew S" last="Miller">Matthew S. Miller</name>
</author>
<author><name sortKey="Hallman, Stacey A" sort="Hallman, Stacey A" uniqKey="Hallman S" first="Stacey A" last="Hallman">Stacey A. Hallman</name>
</author>
<author><name sortKey="Bourbeau, Robert" sort="Bourbeau, Robert" uniqKey="Bourbeau R" first="Robert" last="Bourbeau">Robert Bourbeau</name>
</author>
<author><name sortKey="Herring, D Ann" sort="Herring, D Ann" uniqKey="Herring D" first="D Ann" last="Herring">D Ann Herring</name>
</author>
<author><name sortKey="Earn, David J D" sort="Earn, David J D" uniqKey="Earn D" first="David J D" last="Earn">David J D. Earn</name>
</author>
<author><name sortKey="Madrenas, Joaquin" sort="Madrenas, Joaquin" uniqKey="Madrenas J" first="Joaquín" last="Madrenas">Joaquín Madrenas</name>
</author>
</analytic>
<series><title level="j">PloS one</title>
<idno type="eISSN">1932-6203</idno>
<imprint><date when="2013" type="published">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Age Distribution</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Canada (epidemiology)</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Infant, Newborn</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (mortality)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pandemics (statistics & numerical data)</term>
<term>United States (epidemiology)</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Canada (épidémiologie)</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Grippe humaine (mortalité)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Nouveau-né</term>
<term>Pandémies ()</term>
<term>Répartition par âge</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>États-Unis d'Amérique (épidémiologie)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Canada</term>
<term>United States</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Pandemics</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Canada</term>
<term>Grippe humaine</term>
<term>États-Unis d'Amérique</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Age Distribution</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Infant, Newborn</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Nouveau-né</term>
<term>Pandémies</term>
<term>Répartition par âge</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Canada</term>
<term>États-Unis</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The worldwide spread of a novel influenza A (H1N1) virus in 2009 showed that influenza remains a significant health threat, even for individuals in the prime of life. This paper focuses on the unusually high young adult mortality observed during the Spanish flu pandemic of 1918. Using historical records from Canada and the U.S., we report a peak of mortality at the exact age of 28 during the pandemic and argue that this increased mortality resulted from an early life exposure to influenza during the previous Russian flu pandemic of 1889-90. We posit that in specific instances, development of immunological memory to an influenza virus strain in early life may lead to a dysregulated immune response to antigenically novel strains encountered in later life, thereby increasing the risk of death. Exposure during critical periods of development could also create holes in the T cell repertoire and impair fetal maturation in general, thereby increasing mortality from infectious diseases later in life. Knowledge of the age-pattern of susceptibility to mortality from influenza could improve crisis management during future influenza pandemics. </div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23940526</PMID>
<DateCompleted><Year>2014</Year>
<Month>03</Month>
<Day>05</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Electronic-Print"><Journal><ISSN IssnType="Electronic">1932-6203</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>8</Volume>
<Issue>8</Issue>
<PubDate><Year>2013</Year>
</PubDate>
</JournalIssue>
<Title>PloS one</Title>
<ISOAbbreviation>PLoS ONE</ISOAbbreviation>
</Journal>
<ArticleTitle>Age-specific mortality during the 1918 influenza pandemic: unravelling the mystery of high young adult mortality.</ArticleTitle>
<Pagination><MedlinePgn>e69586</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0069586</ELocationID>
<Abstract><AbstractText>The worldwide spread of a novel influenza A (H1N1) virus in 2009 showed that influenza remains a significant health threat, even for individuals in the prime of life. This paper focuses on the unusually high young adult mortality observed during the Spanish flu pandemic of 1918. Using historical records from Canada and the U.S., we report a peak of mortality at the exact age of 28 during the pandemic and argue that this increased mortality resulted from an early life exposure to influenza during the previous Russian flu pandemic of 1889-90. We posit that in specific instances, development of immunological memory to an influenza virus strain in early life may lead to a dysregulated immune response to antigenically novel strains encountered in later life, thereby increasing the risk of death. Exposure during critical periods of development could also create holes in the T cell repertoire and impair fetal maturation in general, thereby increasing mortality from infectious diseases later in life. Knowledge of the age-pattern of susceptibility to mortality from influenza could improve crisis management during future influenza pandemics. </AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gagnon</LastName>
<ForeName>Alain</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Département de Démographie, Université de Montréal, Montreal, Quebec, Canada. alain.gagnon.4@umontreal.ca</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Miller</LastName>
<ForeName>Matthew S</ForeName>
<Initials>MS</Initials>
</Author>
<Author ValidYN="Y"><LastName>Hallman</LastName>
<ForeName>Stacey A</ForeName>
<Initials>SA</Initials>
</Author>
<Author ValidYN="Y"><LastName>Bourbeau</LastName>
<ForeName>Robert</ForeName>
<Initials>R</Initials>
</Author>
<Author ValidYN="Y"><LastName>Herring</LastName>
<ForeName>D Ann</ForeName>
<Initials>DA</Initials>
</Author>
<Author ValidYN="Y"><LastName>Earn</LastName>
<ForeName>David J D</ForeName>
<Initials>DJ</Initials>
</Author>
<Author ValidYN="Y"><LastName>Madrenas</LastName>
<ForeName>Joaquín</ForeName>
<Initials>J</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2013</Year>
<Month>08</Month>
<Day>05</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>PLoS One</MedlineTA>
<NlmUniqueID>101285081</NlmUniqueID>
<ISSNLinking>1932-6203</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017677" MajorTopicYN="N">Age Distribution</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002170" MajorTopicYN="N" Type="Geographic">Canada</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007231" MajorTopicYN="N">Infant, Newborn</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014481" MajorTopicYN="N" Type="Geographic">United States</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year>
<Month>03</Month>
<Day>06</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2013</Year>
<Month>06</Month>
<Day>09</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2013</Year>
<Month>8</Month>
<Day>14</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2013</Year>
<Month>8</Month>
<Day>14</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2014</Year>
<Month>3</Month>
<Day>7</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">23940526</ArticleId>
<ArticleId IdType="doi">10.1371/journal.pone.0069586</ArticleId>
<ArticleId IdType="pii">PONE-D-13-09397</ArticleId>
<ArticleId IdType="pmc">PMC3734171</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Nat Rev Immunol. 2012 Apr;12(4):295-305</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22402670</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Public Health. 2013 Jul;103(7):e83-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23678911</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2007 Jan 18;445(7125):267-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17230179</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Med. 2004 Dec;10(12 Suppl):S82-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15577936</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 1994 Jun 2;369(6479):407-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8196768</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Soc Hist Med. 1995 Apr;8(1):55-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11639616</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2007 Jan 18;445(7125):319-23</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17230189</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Ann Intern Med. 1953 Aug;39(2):203-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">13080880</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>MBio. 2011;2(5). pii: e00150-11. doi: 10.1128/mBio.00150-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21878571</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2012 Feb;18(2):201-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22306191</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 2011 Jul 22;29 Suppl 2:B21-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21757099</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Immunol. 2004 Jul;4(7):553-64</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15229474</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Bull World Health Organ. 1999;77(10):820-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10593030</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2001 Oct 15;33(8):1375-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11565078</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 2009 Sep 1;183(5):3294-301</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19648276</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2012;8(7):e1002802</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22829765</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Eur J Clin Nutr. 1992 Oct;46 Suppl 3:S3-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1425543</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Soc Sci Med. 2009 May;68(9):1583-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19286293</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Epidemiol. 2003 Apr;32(2):286-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12714551</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Immunol. 2012 Jul;144(1):57-69</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22673491</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 1994 Feb 15;152(4):1653-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8120375</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Can Med Assoc J. 1919 Apr;9(4):339-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20311251</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Immunol. 2005 Oct;5(10):772-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16200080</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Hum Biol. 2012 Sep-Oct;24(5):654-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22777792</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2264-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8637861</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Immunity. 2012 Feb 24;36(2):288-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22365666</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Immunol. 2007 Nov;8(11):1188-93</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17952044</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2013;8(5):e64198</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23717567</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Popul Dev Rev. 2000;26(3):565-81</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19530360</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Meet Amer Climatol Assoc. 1892;8:109-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21407288</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Theor Biol. 2011 Nov 7;288:29-34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21856313</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Infect Dis. 2010;10:5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20059763</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Epidemics. 2011 Mar;3(1):46-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21420659</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2007 Apr 1;195(7):1018-28</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17330793</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Respir Crit Care Med. 1994 Mar;149(3 Pt 1):616-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8118627</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Genet Syst. 2011;86(5):287-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22362027</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 2013 Mar 15;190(6):2736-46</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23408839</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2010 Dec;16(12):1931-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21122224</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Phys Anthropol. 2009 Aug;139(4):584-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19280673</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 2009 Oct 23;27(45):6363-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19840674</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2010 May 11;107(19):8778-81</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20421481</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Theor Popul Biol. 2004 Mar;65(2):179-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14766191</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pediatr Res. 1999 Dec;46(6):641-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10590017</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2006 Jan;12(1):15-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16494711</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2013 Mar 1;207(5):721-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23230061</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000969 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000969 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= PandemieGrippaleV1 |flux= PubMed |étape= Curation |type= RBID |clé= pubmed:23940526 |texte= Age-specific mortality during the 1918 influenza pandemic: unravelling the mystery of high young adult mortality. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:23940526" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \ | NlmPubMed2Wicri -a PandemieGrippaleV1
![]() | This area was generated with Dilib version V0.6.34. | ![]() |