Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus.
Identifieur interne : 000412 ( PubMed/Checkpoint ); précédent : 000411; suivant : 000413Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus.
Auteurs : Amali E. Samarasinghe [États-Unis] ; Rossana C N. Melo [Brésil] ; Susu Duan [États-Unis] ; Kim S. Lemessurier [États-Unis] ; Swantje Liedmann [États-Unis] ; Sherri L. Surman [États-Unis] ; James J. Lee [États-Unis] ; Julia L. Hurwitz [États-Unis] ; Paul G. Thomas [États-Unis] ; Jonathan A. Mccullers [États-Unis]Source :
- Journal of immunology (Baltimore, Md. : 1950) [ 1550-6606 ] ; 2017.
Descripteurs français
- KwdFr :
- Activation des lymphocytes (immunologie), Animaux, Asthme (), Asthme (immunologie), Cytométrie en flux, Granulocytes éosinophiles (immunologie), Hypersensibilité (), Hypersensibilité (immunologie), Infections à Orthomyxoviridae (), Infections à Orthomyxoviridae (immunologie), Lymphocytes T CD8+ (immunologie), Microscopie confocale, Microscopie électronique à transmission, Modèles animaux de maladie humaine, Poumon éosinophile (immunologie), Souris, Virus de la grippe A (immunologie).
- MESH :
- immunologie : Activation des lymphocytes, Asthme, Granulocytes éosinophiles, Hypersensibilité, Infections à Orthomyxoviridae, Lymphocytes T CD8+, Poumon éosinophile, Virus de la grippe A.
- Animaux, Asthme, Cytométrie en flux, Hypersensibilité, Infections à Orthomyxoviridae, Microscopie confocale, Microscopie électronique à transmission, Modèles animaux de maladie humaine, Souris.
English descriptors
- KwdEn :
- Animals, Asthma (complications), Asthma (immunology), CD8-Positive T-Lymphocytes (immunology), Disease Models, Animal, Eosinophils (immunology), Flow Cytometry, Hypersensitivity (complications), Hypersensitivity (immunology), Influenza A virus (immunology), Lymphocyte Activation (immunology), Mice, Microscopy, Confocal, Microscopy, Electron, Transmission, Orthomyxoviridae Infections (complications), Orthomyxoviridae Infections (immunology), Pulmonary Eosinophilia (immunology).
- MESH :
- complications : Asthma, Hypersensitivity, Orthomyxoviridae Infections.
- immunology : Asthma, CD8-Positive T-Lymphocytes, Eosinophils, Hypersensitivity, Influenza A virus, Lymphocyte Activation, Orthomyxoviridae Infections, Pulmonary Eosinophilia.
- Animals, Disease Models, Animal, Flow Cytometry, Mice, Microscopy, Confocal, Microscopy, Electron, Transmission.
Abstract
Eosinophils are multifunctional cells of the innate immune system linked to allergic inflammation. Asthmatics were more likely to be hospitalized but less likely to suffer severe morbidity and mortality during the 2009 influenza pandemic. These epidemiologic findings were recapitulated in a mouse model of fungal asthma wherein infection during heightened allergic inflammation was protective against influenza A virus (IAV) infection and disease. Our goal was to delineate a mechanism(s) by which allergic asthma may alleviate influenza disease outcome, focused on the hypothesis that pulmonary eosinophilia linked with allergic respiratory disease is able to promote antiviral host defenses against the influenza virus. The transfer of eosinophils from the lungs of allergen-sensitized and challenged mice into influenza virus-infected mice resulted in reduced morbidity and viral burden, improved lung compliance, and increased CD8+ T cell numbers in the airways. In vitro assays with primary or bone marrow-derived eosinophils were used to determine eosinophil responses to the virus using the laboratory strain (A/PR/08/1934) or the pandemic strain (A/CA/04/2009) of IAV. Eosinophils were susceptible to IAV infection and responded by activation, piecemeal degranulation, and upregulation of Ag presentation markers. Virus- or viral peptide-exposed eosinophils induced CD8+ T cell proliferation, activation, and effector functions. Our data suggest that eosinophils promote host cellular immunity to reduce influenza virus replication in lungs, thereby providing a novel mechanism by which hosts with allergic asthma may be protected from influenza morbidity.
DOI: 10.4049/jimmunol.1600787
PubMed: 28283567
Affiliations:
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Samarasinghe</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103; asamaras@uthsc.edu.</nlm:affiliation><country wicri:rule="url">États-Unis</country><wicri:regionArea>Department of Pediatrics, University of Tennessee Health Science Center, Memphis</wicri:regionArea><wicri:noRegion>Memphis</wicri:noRegion></affiliation></author><author><name sortKey="Melo, Rossana C N" sort="Melo, Rossana C N" uniqKey="Melo R" first="Rossana C N" last="Melo">Rossana C N. 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Surman</name><affiliation wicri:level="2"><nlm:affiliation>Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Lee, James J" sort="Lee, James J" uniqKey="Lee J" first="James J" last="Lee">James J. Lee</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry, Mayo Clinic, Scottsdale, AZ 85259.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Arizona</region></placeName><wicri:cityArea>Department of Biochemistry, Mayo Clinic, Scottsdale</wicri:cityArea></affiliation></author><author><name sortKey="Hurwitz, Julia L" sort="Hurwitz, Julia L" uniqKey="Hurwitz J" first="Julia L" last="Hurwitz">Julia L. Hurwitz</name><affiliation wicri:level="2"><nlm:affiliation>Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Thomas, Paul G" sort="Thomas, Paul G" uniqKey="Thomas P" first="Paul G" last="Thomas">Paul G. Thomas</name><affiliation wicri:level="2"><nlm:affiliation>Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105; and.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Immunology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Mccullers, Jonathan A" sort="Mccullers, Jonathan A" uniqKey="Mccullers J" first="Jonathan A" last="Mccullers">Jonathan A. Mccullers</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Pediatrics, University of Tennessee Health Science Center, Memphis</wicri:cityArea></affiliation></author></analytic><series><title level="j">Journal of immunology (Baltimore, Md. : 1950)</title><idno type="eISSN">1550-6606</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Asthma (complications)</term><term>Asthma (immunology)</term><term>CD8-Positive T-Lymphocytes (immunology)</term><term>Disease Models, Animal</term><term>Eosinophils (immunology)</term><term>Flow Cytometry</term><term>Hypersensitivity (complications)</term><term>Hypersensitivity (immunology)</term><term>Influenza A virus (immunology)</term><term>Lymphocyte Activation (immunology)</term><term>Mice</term><term>Microscopy, Confocal</term><term>Microscopy, Electron, Transmission</term><term>Orthomyxoviridae Infections (complications)</term><term>Orthomyxoviridae Infections (immunology)</term><term>Pulmonary Eosinophilia (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Activation des lymphocytes (immunologie)</term><term>Animaux</term><term>Asthme ()</term><term>Asthme (immunologie)</term><term>Cytométrie en flux</term><term>Granulocytes éosinophiles (immunologie)</term><term>Hypersensibilité ()</term><term>Hypersensibilité (immunologie)</term><term>Infections à Orthomyxoviridae ()</term><term>Infections à Orthomyxoviridae (immunologie)</term><term>Lymphocytes T CD8+ (immunologie)</term><term>Microscopie confocale</term><term>Microscopie électronique à transmission</term><term>Modèles animaux de maladie humaine</term><term>Poumon éosinophile (immunologie)</term><term>Souris</term><term>Virus de la grippe A (immunologie)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Asthma</term><term>Hypersensitivity</term><term>Orthomyxoviridae Infections</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Activation des lymphocytes</term><term>Asthme</term><term>Granulocytes éosinophiles</term><term>Hypersensibilité</term><term>Infections à Orthomyxoviridae</term><term>Lymphocytes T CD8+</term><term>Poumon éosinophile</term><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Asthma</term><term>CD8-Positive T-Lymphocytes</term><term>Eosinophils</term><term>Hypersensitivity</term><term>Influenza A virus</term><term>Lymphocyte Activation</term><term>Orthomyxoviridae Infections</term><term>Pulmonary Eosinophilia</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Disease Models, Animal</term><term>Flow Cytometry</term><term>Mice</term><term>Microscopy, Confocal</term><term>Microscopy, Electron, Transmission</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Asthme</term><term>Cytométrie en flux</term><term>Hypersensibilité</term><term>Infections à Orthomyxoviridae</term><term>Microscopie confocale</term><term>Microscopie électronique à transmission</term><term>Modèles animaux de maladie humaine</term><term>Souris</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Eosinophils are multifunctional cells of the innate immune system linked to allergic inflammation. Asthmatics were more likely to be hospitalized but less likely to suffer severe morbidity and mortality during the 2009 influenza pandemic. These epidemiologic findings were recapitulated in a mouse model of fungal asthma wherein infection during heightened allergic inflammation was protective against influenza A virus (IAV) infection and disease. Our goal was to delineate a mechanism(s) by which allergic asthma may alleviate influenza disease outcome, focused on the hypothesis that pulmonary eosinophilia linked with allergic respiratory disease is able to promote antiviral host defenses against the influenza virus. The transfer of eosinophils from the lungs of allergen-sensitized and challenged mice into influenza virus-infected mice resulted in reduced morbidity and viral burden, improved lung compliance, and increased CD8<sup>+</sup> T cell numbers in the airways. In vitro assays with primary or bone marrow-derived eosinophils were used to determine eosinophil responses to the virus using the laboratory strain (A/PR/08/1934) or the pandemic strain (A/CA/04/2009) of IAV. Eosinophils were susceptible to IAV infection and responded by activation, piecemeal degranulation, and upregulation of Ag presentation markers. Virus- or viral peptide-exposed eosinophils induced CD8<sup>+</sup> T cell proliferation, activation, and effector functions. Our data suggest that eosinophils promote host cellular immunity to reduce influenza virus replication in lungs, thereby providing a novel mechanism by which hosts with allergic asthma may be protected from influenza morbidity.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28283567</PMID><DateCompleted><Year>2017</Year><Month>09</Month><Day>12</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1550-6606</ISSN><JournalIssue CitedMedium="Internet"><Volume>198</Volume><Issue>8</Issue><PubDate><Year>2017</Year><Month>04</Month><Day>15</Day></PubDate></JournalIssue><Title>Journal of immunology (Baltimore, Md. : 1950)</Title><ISOAbbreviation>J. Immunol.</ISOAbbreviation></Journal><ArticleTitle>Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus.</ArticleTitle><Pagination><MedlinePgn>3214-3226</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.4049/jimmunol.1600787</ELocationID><Abstract><AbstractText>Eosinophils are multifunctional cells of the innate immune system linked to allergic inflammation. Asthmatics were more likely to be hospitalized but less likely to suffer severe morbidity and mortality during the 2009 influenza pandemic. These epidemiologic findings were recapitulated in a mouse model of fungal asthma wherein infection during heightened allergic inflammation was protective against influenza A virus (IAV) infection and disease. Our goal was to delineate a mechanism(s) by which allergic asthma may alleviate influenza disease outcome, focused on the hypothesis that pulmonary eosinophilia linked with allergic respiratory disease is able to promote antiviral host defenses against the influenza virus. The transfer of eosinophils from the lungs of allergen-sensitized and challenged mice into influenza virus-infected mice resulted in reduced morbidity and viral burden, improved lung compliance, and increased CD8<sup>+</sup> T cell numbers in the airways. In vitro assays with primary or bone marrow-derived eosinophils were used to determine eosinophil responses to the virus using the laboratory strain (A/PR/08/1934) or the pandemic strain (A/CA/04/2009) of IAV. Eosinophils were susceptible to IAV infection and responded by activation, piecemeal degranulation, and upregulation of Ag presentation markers. Virus- or viral peptide-exposed eosinophils induced CD8<sup>+</sup> T cell proliferation, activation, and effector functions. Our data suggest that eosinophils promote host cellular immunity to reduce influenza virus replication in lungs, thereby providing a novel mechanism by which hosts with allergic asthma may be protected from influenza morbidity.</AbstractText><CopyrightInformation>Copyright © 2017 by The American Association of Immunologists, Inc.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Samarasinghe</LastName><ForeName>Amali E</ForeName><Initials>AE</Initials><Identifier Source="ORCID">0000-0002-3104-2823</Identifier><AffiliationInfo><Affiliation>Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103; asamaras@uthsc.edu.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Children's Foundation Research Institute, Memphis, TN 38103.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Melo</LastName><ForeName>Rossana C N</ForeName><Initials>RC</Initials><Identifier Source="ORCID">0000-0003-1736-0806</Identifier><AffiliationInfo><Affiliation>Laboratory of Cellular Biology, Federal University of Juiz de Fora, Juiz de Fora, MG 36036, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Duan</LastName><ForeName>Susu</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105; and.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>LeMessurier</LastName><ForeName>Kim S</ForeName><Initials>KS</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Children's Foundation Research Institute, Memphis, TN 38103.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liedmann</LastName><ForeName>Swantje</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105; and.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Surman</LastName><ForeName>Sherri L</ForeName><Initials>SL</Initials><Identifier Source="ORCID">0000-0003-4199-661X</Identifier><AffiliationInfo><Affiliation>Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>James J</ForeName><Initials>JJ</Initials><AffiliationInfo><Affiliation>Department of Biochemistry, Mayo Clinic, Scottsdale, AZ 85259.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hurwitz</LastName><ForeName>Julia L</ForeName><Initials>JL</Initials><AffiliationInfo><Affiliation>Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thomas</LastName><ForeName>Paul G</ForeName><Initials>PG</Initials><AffiliationInfo><Affiliation>Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105; and.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McCullers</LastName><ForeName>Jonathan A</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Children's Foundation Research Institute, Memphis, TN 38103.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList 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Immunol</MedlineTA><NlmUniqueID>2985117R</NlmUniqueID><ISSNLinking>0022-1767</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001249" MajorTopicYN="N">Asthma</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018414" MajorTopicYN="N">CD8-Positive T-Lymphocytes</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004195" MajorTopicYN="N">Disease Models, Animal</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004804" MajorTopicYN="N">Eosinophils</DescriptorName><QualifierName UI="Q000276" 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PubStatus="pubmed"><Year>2017</Year><Month>3</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>3</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28283567</ArticleId><ArticleId IdType="pii">jimmunol.1600787</ArticleId><ArticleId IdType="doi">10.4049/jimmunol.1600787</ArticleId><ArticleId IdType="pmc">PMC5384374</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Immunol Allergy Clin North Am. 2007 Aug;27(3):457-75</Citation><ArticleIdList><ArticleId IdType="pubmed">17868859</ArticleId></ArticleIdList></Reference><Reference><Citation>J Leukoc Biol. 2009 Jan;85(1):117-23</Citation><ArticleIdList><ArticleId IdType="pubmed">18840671</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Respir Crit Care Med. 1995 Mar;151(3 Pt 1):879-86</Citation><ArticleIdList><ArticleId IdType="pubmed">7881686</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2000 Jun;74(12):5460-9</Citation><ArticleIdList><ArticleId IdType="pubmed">10823850</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2015 Sep 4;349(6252):aaa4352</Citation><ArticleIdList><ArticleId IdType="pubmed">26339033</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Exp Allergy. 2010 Apr;40(4):563-75</Citation><ArticleIdList><ArticleId IdType="pubmed">20447076</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2009 Nov 12;361(20):1935-44</Citation><ArticleIdList><ArticleId IdType="pubmed">19815859</ArticleId></ArticleIdList></Reference><Reference><Citation>World J Crit Care Med. 2016 Feb 04;5(1):89-95</Citation><ArticleIdList><ArticleId IdType="pubmed">26855898</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Med. 1999 Aug 16;190(4):487-95</Citation><ArticleIdList><ArticleId IdType="pubmed">10449520</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 1981 May;126(5):1814-9</Citation><ArticleIdList><ArticleId IdType="pubmed">7217668</ArticleId></ArticleIdList></Reference><Reference><Citation>Blood. 2007 Sep 1;110(5):1578-86</Citation><ArticleIdList><ArticleId IdType="pubmed">17495130</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2003 Oct 1;171(7):3372-8</Citation><ArticleIdList><ArticleId IdType="pubmed">14500630</ArticleId></ArticleIdList></Reference><Reference><Citation>Allergy. 2015 Sep;70(9):1148-59</Citation><ArticleIdList><ArticleId IdType="pubmed">26009788</ArticleId></ArticleIdList></Reference><Reference><Citation>Fungal Biol. 2011 Jan;115(1):21-9</Citation><ArticleIdList><ArticleId IdType="pubmed">21215951</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Immunol. 2015 Jun;16(6):609-17</Citation><ArticleIdList><ArticleId IdType="pubmed">25915731</ArticleId></ArticleIdList></Reference><Reference><Citation>Blood. 2014 Jan 30;123(5):743-52</Citation><ArticleIdList><ArticleId IdType="pubmed">24297871</ArticleId></ArticleIdList></Reference><Reference><Citation>Allergy. 2004 Apr;59(4):428-35</Citation><ArticleIdList><ArticleId IdType="pubmed">15005767</ArticleId></ArticleIdList></Reference><Reference><Citation>Pediatr Res. 1992 Aug;32(2):160-4</Citation><ArticleIdList><ArticleId IdType="pubmed">1324464</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2011 Dec 1;187(11):6059-68</Citation><ArticleIdList><ArticleId IdType="pubmed">22048766</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Immunol. 2002 Apr;2(4):251-62</Citation><ArticleIdList><ArticleId IdType="pubmed">12001996</ArticleId></ArticleIdList></Reference><Reference><Citation>Influenza Other Respir Viruses. 2012 Nov;6(6):e134-42</Citation><ArticleIdList><ArticleId IdType="pubmed">22672249</ArticleId></ArticleIdList></Reference><Reference><Citation>Blood. 2009 Sep 24;114(13):2649-56</Citation><ArticleIdList><ArticleId IdType="pubmed">19652202</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Microbiol Infect. 2015 Oct;21(10):956-63</Citation><ArticleIdList><ArticleId IdType="pubmed">26123860</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Invest. 1996 Apr 1;97(7):1761-6</Citation><ArticleIdList><ArticleId IdType="pubmed">8601642</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur J Immunol. 1992 Jul;22(7):1919-25</Citation><ArticleIdList><ArticleId IdType="pubmed">1623930</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2001 Sep 15;167(6):3146-55</Citation><ArticleIdList><ArticleId IdType="pubmed">11544300</ArticleId></ArticleIdList></Reference><Reference><Citation>Thorax. 2010 Jul;65(7):645-51</Citation><ArticleIdList><ArticleId IdType="pubmed">20627925</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2000 Aug 15;165(4):1965-75</Citation><ArticleIdList><ArticleId IdType="pubmed">10925279</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 1998 Dec 1;26(23):5327-32</Citation><ArticleIdList><ArticleId IdType="pubmed">9826755</ArticleId></ArticleIdList></Reference><Reference><Citation>Pediatrics. 2011 Jul;128(1):e27-32</Citation><ArticleIdList><ArticleId IdType="pubmed">21646257</ArticleId></ArticleIdList></Reference><Reference><Citation>J Allergy Clin Immunol. 2004 Oct;114(4):820-5</Citation><ArticleIdList><ArticleId IdType="pubmed">15480321</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 1993 Mar 15;150(6):2554-62</Citation><ArticleIdList><ArticleId IdType="pubmed">8450230</ArticleId></ArticleIdList></Reference><Reference><Citation>Diabetes Care. 2010 Jul;33(7):1491-3</Citation><ArticleIdList><ArticleId IdType="pubmed">20587722</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2006 Jul;80(13):6295-304</Citation><ArticleIdList><ArticleId IdType="pubmed">16775317</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2007 Dec 1;179(11):7585-92</Citation><ArticleIdList><ArticleId IdType="pubmed">18025204</ArticleId></ArticleIdList></Reference><Reference><Citation>Euro Surveill. 2009 Aug 20;14(33):null</Citation><ArticleIdList><ArticleId IdType="pubmed">19712643</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur Respir J. 2013 Apr;41(4):824-31</Citation><ArticleIdList><ArticleId IdType="pubmed">22903963</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 1992 Dec 1;149(11):3710-8</Citation><ArticleIdList><ArticleId IdType="pubmed">1358975</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 1998 Jul 15;26(14):3358-63</Citation><ArticleIdList><ArticleId IdType="pubmed">9649619</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Invest. 2010 Jun;120(6):1885-94</Citation><ArticleIdList><ArticleId IdType="pubmed">20440073</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Immunol. 2012;273(2):158-63</Citation><ArticleIdList><ArticleId IdType="pubmed">22248881</ArticleId></ArticleIdList></Reference><Reference><Citation>Histol Histopathol. 2010 Oct;25(10 ):1341-54</Citation><ArticleIdList><ArticleId IdType="pubmed">20712018</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 1997 Dec 1;159(11):5197-200</Citation><ArticleIdList><ArticleId IdType="pubmed">9548456</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Med. 2011 Jul;8(7):e1001053</Citation><ArticleIdList><ArticleId IdType="pubmed">21750667</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1991 May 1;88(9):3972-6</Citation><ArticleIdList><ArticleId IdType="pubmed">1902576</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 1995 Oct;69(10):6359-66</Citation><ArticleIdList><ArticleId IdType="pubmed">7666537</ArticleId></ArticleIdList></Reference><Reference><Citation>Int Immunol. 1994 Mar;6(3):369-76</Citation><ArticleIdList><ArticleId IdType="pubmed">8186188</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Med. 1992 Apr 1;175(4):1143-5</Citation><ArticleIdList><ArticleId IdType="pubmed">1552285</ArticleId></ArticleIdList></Reference><Reference><Citation>Immunol Cell Biol. 2012 Feb;90(2):197-205</Citation><ArticleIdList><ArticleId IdType="pubmed">21483446</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Respir Cell Mol Biol. 2016 Sep;55(3):387-94</Citation><ArticleIdList><ArticleId IdType="pubmed">27049514</ArticleId></ArticleIdList></Reference><Reference><Citation>Med Mycol. 2010 Dec;48(8):1056-65</Citation><ArticleIdList><ArticleId IdType="pubmed">20482452</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2011 Mar 14;6(3):e17618</Citation><ArticleIdList><ArticleId IdType="pubmed">21423798</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Infect Dis. 2013 Jan 31;13:57</Citation><ArticleIdList><ArticleId IdType="pubmed">23369034</ArticleId></ArticleIdList></Reference><Reference><Citation>Immunol Cell Biol. 2014 May-Jun;92(5):449-59</Citation><ArticleIdList><ArticleId IdType="pubmed">24469764</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1989 Feb;86(4):1348-51</Citation><ArticleIdList><ArticleId IdType="pubmed">2919183</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2004 Nov 15;173(10):6134-42</Citation><ArticleIdList><ArticleId IdType="pubmed">15528350</ArticleId></ArticleIdList></Reference><Reference><Citation>Influenza Other Respir Viruses. 2011 Jul;5(4):247-55</Citation><ArticleIdList><ArticleId IdType="pubmed">21651735</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Med. 1999 Nov 15;190(10):1465-78</Citation><ArticleIdList><ArticleId IdType="pubmed">10562321</ArticleId></ArticleIdList></Reference><Reference><Citation>J Leukoc Biol. 2008 Mar;83(3):456-60</Citation><ArticleIdList><ArticleId IdType="pubmed">17991762</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Med. 2015 Oct;21(10):1216-22</Citation><ArticleIdList><ArticleId IdType="pubmed">26413780</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Invest. 2000 Apr;105(7):945-53</Citation><ArticleIdList><ArticleId IdType="pubmed">10749574</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2009 Dec 1;183(11):7441-50</Citation><ArticleIdList><ArticleId IdType="pubmed">19917678</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2008 Sep 15;181(6):4004-9</Citation><ArticleIdList><ArticleId IdType="pubmed">18768855</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA. 2009 Nov 4;302(17):1896-902</Citation><ArticleIdList><ArticleId IdType="pubmed">19887665</ArticleId></ArticleIdList></Reference><Reference><Citation>Inflamm Res. 2014 Jun;63(6):475-84</Citation><ArticleIdList><ArticleId IdType="pubmed">24519432</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Med. 2003 Aug 4;198(3):399-410</Citation><ArticleIdList><ArticleId IdType="pubmed">12885871</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Brésil</li><li>États-Unis</li></country><region><li>Arizona</li><li>Tennessee</li></region></list><tree><country name="États-Unis"><noRegion><name sortKey="Samarasinghe, Amali E" sort="Samarasinghe, Amali E" uniqKey="Samarasinghe A" 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