Factors involved in the aerosol transmission of infection and control of ventilation in healthcare premises
Identifieur interne : 000E54 ( Pmc/Checkpoint ); précédent : 000E53; suivant : 000E55Factors involved in the aerosol transmission of infection and control of ventilation in healthcare premises
Auteurs : J. W. Tang [République populaire de Chine] ; Y. Li [République populaire de Chine] ; I. Eames [Royaume-Uni] ; P. K. S. Chan [République populaire de Chine] ; G. L. Ridgway [Royaume-Uni]Source :
- The Journal of Hospital Infection [ 0195-6701 ] ; 2006.
Abstract
The epidemics of severe acute respiratory syndrome (SARS) in 2003 highlighted both short- and long-range transmission routes, i.e. between infected patients and healthcare workers, and between distant locations. With other infections such as tuberculosis, measles and chickenpox, the concept of aerosol transmission is so well accepted that isolation of such patients is the norm. With current concerns about a possible approaching influenza pandemic, the control of transmission via infectious air has become more important. Therefore, the aim of this review is to describe the factors involved in: (1) the generation of an infectious aerosol, (2) the transmission of infectious droplets or droplet nuclei from this aerosol, and (3) the potential for inhalation of such droplets or droplet nuclei by a susceptible host. On this basis, recommendations are made to improve the control of aerosol-transmitted infections in hospitals as well as in the design and construction of future isolation facilities.
Url:
DOI: 10.1016/j.jhin.2006.05.022
PubMed: 16916564
PubMed Central: 7114857
Affiliations:
- Royaume-Uni, République populaire de Chine
- Angleterre, Grand Londres
- Londres, Sha Tin
- University College de Londres, Université chinoise de Hong Kong
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W." last="Tang">J. W. Tang</name><affiliation wicri:level="4"><nlm:aff id="aff1">Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Li, Y" sort="Li, Y" uniqKey="Li Y" first="Y." last="Li">Y. Li</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Mechanical Engineering, The University of Hong Kong, Pokfulam, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Mechanical Engineering, The University of Hong Kong, Pokfulam, Hong Kong SAR</wicri:regionArea><wicri:noRegion>Hong Kong SAR</wicri:noRegion></affiliation></author><author><name sortKey="Eames, I" sort="Eames, I" uniqKey="Eames I" first="I." last="Eames">I. Eames</name><affiliation wicri:level="4"><nlm:aff id="aff3">Department of Mechanical Engineering, University College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Mechanical Engineering, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Chan, P K S" sort="Chan, P K S" uniqKey="Chan P" first="P. K. S." last="Chan">P. K. S. Chan</name><affiliation wicri:level="4"><nlm:aff id="aff1">Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff4">School of Public Health, The Chinese University of Hong Kong, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Public Health, The Chinese University of Hong Kong, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Ridgway, G L" sort="Ridgway, G L" uniqKey="Ridgway G" first="G. L." last="Ridgway">G. L. Ridgway</name><affiliation wicri:level="3"><nlm:aff id="aff5">Capital Investment and Planning, University College London Hospitals, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Capital Investment and Planning, University College London Hospitals, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></analytic><series><title level="j">The Journal of Hospital Infection</title><idno type="ISSN">0195-6701</idno><idno type="eISSN">1532-2939</idno><imprint><date when="2006">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p>The epidemics of severe acute respiratory syndrome (SARS) in 2003 highlighted both short- and long-range transmission routes, i.e. between infected patients and healthcare workers, and between distant locations. With other infections such as tuberculosis, measles and chickenpox, the concept of aerosol transmission is so well accepted that isolation of such patients is the norm. With current concerns about a possible approaching influenza pandemic, the control of transmission via infectious air has become more important. Therefore, the aim of this review is to describe the factors involved in: (1) the generation of an infectious aerosol, (2) the transmission of infectious droplets or droplet nuclei from this aerosol, and (3) the potential for inhalation of such droplets or droplet nuclei by a susceptible host. On this basis, recommendations are made to improve the control of aerosol-transmitted infections in hospitals as well as in the design and construction of future isolation facilities.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Wong, T W" uniqKey="Wong T">T.W. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">J Hosp Infect</journal-id><journal-id journal-id-type="iso-abbrev">J. Hosp. Infect</journal-id><journal-title-group><journal-title>The Journal of Hospital Infection</journal-title></journal-title-group><issn pub-type="ppub">0195-6701</issn><issn pub-type="epub">1532-2939</issn><publisher><publisher-name>The Hospital Infection Society. Published by Elsevier Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">16916564</article-id><article-id pub-id-type="pmc">7114857</article-id><article-id pub-id-type="publisher-id">S0195-6701(06)00286-6</article-id><article-id pub-id-type="doi">10.1016/j.jhin.2006.05.022</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Factors involved in the aerosol transmission of infection and control of ventilation in healthcare premises</article-title></title-group><contrib-group><contrib contrib-type="author" id="au1"><name><surname>Tang</surname><given-names>J.W.</given-names></name><email>jwtang49@hotmail.com</email><xref rid="aff1" ref-type="aff">a</xref><xref rid="cor1" ref-type="corresp">∗</xref></contrib><contrib contrib-type="author" id="au2"><name><surname>Li</surname><given-names>Y.</given-names></name><xref rid="aff2" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="au3"><name><surname>Eames</surname><given-names>I.</given-names></name><xref rid="aff3" ref-type="aff">c</xref></contrib><contrib contrib-type="author" id="au4"><name><surname>Chan</surname><given-names>P.K.S.</given-names></name><xref rid="aff1" ref-type="aff">a</xref><xref rid="aff4" ref-type="aff">d</xref></contrib><contrib contrib-type="author" id="au5"><name><surname>Ridgway</surname><given-names>G.L.</given-names></name><xref rid="aff5" ref-type="aff">e</xref></contrib></contrib-group><aff id="aff1"><label>a</label>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</aff><aff id="aff2"><label>b</label>Department of Mechanical Engineering, The University of Hong Kong, Pokfulam, Hong Kong SAR, China</aff><aff id="aff3"><label>c</label>Department of Mechanical Engineering, University College London, London, UK</aff><aff id="aff4"><label>d</label>School of Public Health, The Chinese University of Hong Kong, Hong Kong SAR, China</aff><aff id="aff5"><label>e</label>Capital Investment and Planning, University College London Hospitals, London, UK</aff><author-notes><corresp id="cor1"><label>∗</label>Corresponding author. Address: Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China. Tel.: +852 2632 3333; fax: +852 2647 3227. <email>jwtang49@hotmail.com</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>17</day><month>8</month><year>2006</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>10</month><year>2006</year></pub-date><pub-date pub-type="epub"><day>17</day><month>8</month><year>2006</year></pub-date><volume>64</volume><issue>2</issue><fpage>100</fpage><lpage>114</lpage><permissions><copyright-statement>Copyright © 2006 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.</copyright-statement><copyright-year>2006</copyright-year><copyright-holder>The Hospital Infection Society</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract><title>Summary</title><p>The epidemics of severe acute respiratory syndrome (SARS) in 2003 highlighted both short- and long-range transmission routes, i.e. between infected patients and healthcare workers, and between distant locations. With other infections such as tuberculosis, measles and chickenpox, the concept of aerosol transmission is so well accepted that isolation of such patients is the norm. With current concerns about a possible approaching influenza pandemic, the control of transmission via infectious air has become more important. Therefore, the aim of this review is to describe the factors involved in: (1) the generation of an infectious aerosol, (2) the transmission of infectious droplets or droplet nuclei from this aerosol, and (3) the potential for inhalation of such droplets or droplet nuclei by a susceptible host. On this basis, recommendations are made to improve the control of aerosol-transmitted infections in hospitals as well as in the design and construction of future isolation facilities.</p></abstract><kwd-group><title>Keywords</title><kwd>Aerosol</kwd><kwd>Transmission</kwd><kwd>SARS</kwd><kwd>Influenza</kwd><kwd>Droplets</kwd><kwd>Control</kwd><kwd>Infection</kwd></kwd-group></article-meta></front></pmc><affiliations><list><country><li>Royaume-Uni</li><li>République populaire de Chine</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li><li>Sha Tin</li></settlement><orgName><li>University College de Londres</li><li>Université chinoise de Hong Kong</li></orgName></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Tang, J W" sort="Tang, J W" uniqKey="Tang J" first="J. W." last="Tang">J. W. Tang</name></noRegion><name sortKey="Chan, P K S" sort="Chan, P K S" uniqKey="Chan P" first="P. K. S." last="Chan">P. K. S. Chan</name><name sortKey="Chan, P K S" sort="Chan, P K S" uniqKey="Chan P" first="P. K. S." last="Chan">P. K. S. Chan</name><name sortKey="Li, Y" sort="Li, Y" uniqKey="Li Y" first="Y." last="Li">Y. Li</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Eames, I" sort="Eames, I" uniqKey="Eames I" first="I." last="Eames">I. Eames</name></region><name sortKey="Ridgway, G L" sort="Ridgway, G L" uniqKey="Ridgway G" first="G. L." last="Ridgway">G. L. Ridgway</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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