PandemieGrippaleV1, PascalFrancis, Curation, bibRecord, 000C41

Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy

Identifieur interne : 000C41 ( PascalFrancis/Curation ); précédent : 000C40; suivant : 000C42

Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy

Auteurs : Alberto Cagigi [Suède] ; Anna Nilsson [Suède] ; Simone Pensieroso [Suède] ; Francesca Chiodi [Suède]

Source :

Lancet. Infectious diseases : (print) [ 1473-3099 ] ; 2010.

RBID : Pascal:10-0325970

Descripteurs français

Pascal (Inist)
- SIDA, Grippe, Immunoprophylaxie, Chimiothérapie, Cellule β, Vaccination, Virus HIV1, Antiviral, Protocole HAART.
Wicri :
- topic : Vaccination.

English descriptors

KwdEn :
- AIDS, Antiviral, Chemotherapy, HIV-1 virus, Immunoprophylaxis, Influenza, Vaccination, β Cell.

Abstract

Although HIV-1 infection does not directly target B cells, B-cell numbers are reduced and their function is impaired during HIV infection. Antibody titres against antigens previously encountered through vaccination or natural infection are low in patients with HIV Intrinsic B-cell defects might be involved in the impairment of humoral immunity during early HIV infection. Abnormal T-cell activation and the altered expression of molecules involved in the B-cell homing process cause dysfunctional interaction between T and B cells in the germinal centres of lymphoid tissues, which might impair B-cell responses during HIV infection. Class-switch recombination is also impaired in individuals with HIV. Protective immune responses against T-cell-dependent antigens, including influenza antigens, rely on the production of neutralising antibodies. Impaired B-cell responses during HIV infection could therefore hamper the effectiveness of vaccinations against seasonal influenza or the new pandemic influenza A H1N1 vaccines in individuals with HIV. By maintaining B-cell responses, highly active antiretroviral therapy might improve the efficacy of influenza vaccines in individuals with HIV.

A01	`01`	`1`		`@0 1473-3099`
A03		`1`		`@0 Lancet. Infect. dis. : (print)`
A05				`@2 10`
A06				`@2 7`
A08	`01`	`1`	`ENG`	`@1 Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy`
A11	`01`	`1`		`@1 CAGIGI (Alberto)`
A11	`02`	`1`		`@1 NILSSON (Anna)`
A11	`03`	`1`		`@1 PENSIEROSO (Simone)`
A11	`04`	`1`		`@1 CHIODI (Francesca)`
A14	`01`			`@1 Department of Laboratory Medicine, Karolinska Institutet @2 Stockholm @3 SWE @Z 1 aut.`
A14	`02`			`@1 Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet @2 Stockholm @3 SWE @Z 2 aut. @Z 3 aut. @Z 4 aut.`
A14	`03`			`@1 Paediatric Infectious Diseases Unit, Department of Women and Child Health, Karolinska Institutet @2 Stockholm @3 SWE @Z 2 aut.`
A20				`@1 499-503`
A21				`@1 2010`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 27478 @5 354000180746180060`
A44				`@0 0000 @1 © 2010 INIST-CNRS. All rights reserved.`
A45				`@0 66 ref.`
A47	`01`	`1`		`@0 10-0325970`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Lancet. Infectious diseases : (print)`
A66	`01`			`@0 GBR`
C01	`01`		`ENG`	@0 Although HIV-1 infection does not directly target B cells, B-cell numbers are reduced and their function is impaired during HIV infection. Antibody titres against antigens previously encountered through vaccination or natural infection are low in patients with HIV Intrinsic B-cell defects might be involved in the impairment of humoral immunity during early HIV infection. Abnormal T-cell activation and the altered expression of molecules involved in the B-cell homing process cause dysfunctional interaction between T and B cells in the germinal centres of lymphoid tissues, which might impair B-cell responses during HIV infection. Class-switch recombination is also impaired in individuals with HIV. Protective immune responses against T-cell-dependent antigens, including influenza antigens, rely on the production of neutralising antibodies. Impaired B-cell responses during HIV infection could therefore hamper the effectiveness of vaccinations against seasonal influenza or the new pandemic influenza A H1N1 vaccines in individuals with HIV. By maintaining B-cell responses, highly active antiretroviral therapy might improve the efficacy of influenza vaccines in individuals with HIV.
C02	`01`	`X`		`@0 002B05C02D`
C02	`02`	`X`		`@0 002B05C02C`
C02	`03`	`X`		`@0 002B06D01`
C03	`01`	`X`	`FRE`	`@0 SIDA @5 01`
C03	`01`	`X`	`ENG`	`@0 AIDS @5 01`
C03	`01`	`X`	`SPA`	`@0 SIDA @5 01`
C03	`02`	`X`	`FRE`	`@0 Grippe @5 02`
C03	`02`	`X`	`ENG`	`@0 Influenza @5 02`
C03	`02`	`X`	`SPA`	`@0 Gripe @5 02`
C03	`03`	`X`	`FRE`	`@0 Immunoprophylaxie @5 04`
C03	`03`	`X`	`ENG`	`@0 Immunoprophylaxis @5 04`
C03	`03`	`X`	`SPA`	`@0 Inmunoprofilaxia @5 04`
C03	`04`	`X`	`FRE`	`@0 Chimiothérapie @5 05`
C03	`04`	`X`	`ENG`	`@0 Chemotherapy @5 05`
C03	`04`	`X`	`SPA`	`@0 Quimioterapia @5 05`
C03	`05`	`X`	`FRE`	`@0 Cellule β @5 07`
C03	`05`	`X`	`ENG`	`@0 β Cell @5 07`
C03	`05`	`X`	`SPA`	`@0 Célula β @5 07`
C03	`06`	`X`	`FRE`	`@0 Vaccination @5 08`
C03	`06`	`X`	`ENG`	`@0 Vaccination @5 08`
C03	`06`	`X`	`SPA`	`@0 Vacunación @5 08`
C03	`07`	`X`	`FRE`	`@0 Virus HIV1 @2 NW @5 10`
C03	`07`	`X`	`ENG`	`@0 HIV-1 virus @2 NW @5 10`
C03	`07`	`X`	`SPA`	`@0 HIV-1 virus @2 NW @5 10`
C03	`08`	`X`	`FRE`	`@0 Antiviral @5 30`
C03	`08`	`X`	`ENG`	`@0 Antiviral @5 30`
C03	`08`	`X`	`SPA`	`@0 Antiviral @5 30`
C03	`09`	`X`	`FRE`	`@0 Protocole HAART @4 INC @5 86`
C07	`01`	`X`	`FRE`	`@0 Virose`
C07	`01`	`X`	`ENG`	`@0 Viral disease`
C07	`01`	`X`	`SPA`	`@0 Virosis`
C07	`02`	`X`	`FRE`	`@0 Infection`
C07	`02`	`X`	`ENG`	`@0 Infection`
C07	`02`	`X`	`SPA`	`@0 Infección`
C07	`03`	`X`	`FRE`	`@0 Traitement`
C07	`03`	`X`	`ENG`	`@0 Treatment`
C07	`03`	`X`	`SPA`	`@0 Tratamiento`
C07	`04`	`X`	`FRE`	`@0 Virus immunodéficience humaine @2 NW`
C07	`04`	`X`	`ENG`	`@0 Human immunodeficiency virus @2 NW`
C07	`04`	`X`	`SPA`	`@0 Human immunodeficiency virus @2 NW`
C07	`05`	`X`	`FRE`	`@0 Lentivirus @2 NW`
C07	`05`	`X`	`ENG`	`@0 Lentivirus @2 NW`
C07	`05`	`X`	`SPA`	`@0 Lentivirus @2 NW`
C07	`06`	`X`	`FRE`	`@0 Retroviridae @2 NW`
C07	`06`	`X`	`ENG`	`@0 Retroviridae @2 NW`
C07	`06`	`X`	`SPA`	`@0 Retroviridae @2 NW`
C07	`07`	`X`	`FRE`	`@0 Virus @2 NW`
C07	`07`	`X`	`ENG`	`@0 Virus @2 NW`
C07	`07`	`X`	`SPA`	`@0 Virus @2 NW`
C07	`08`	`X`	`FRE`	`@0 Immunodéficit @5 37`
C07	`08`	`X`	`ENG`	`@0 Immune deficiency @5 37`
C07	`08`	`X`	`SPA`	`@0 Inmunodeficiencia @5 37`
C07	`09`	`X`	`FRE`	`@0 Immunopathologie @5 39`
C07	`09`	`X`	`ENG`	`@0 Immunopathology @5 39`
C07	`09`	`X`	`SPA`	`@0 Inmunopatología @5 39`
C07	`10`	`X`	`FRE`	`@0 Prévention @5 40`
C07	`10`	`X`	`ENG`	`@0 Prevention @5 40`
C07	`10`	`X`	`SPA`	`@0 Prevención @5 40`
N21				`@1 207`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001228

Links to Exploration step

Pascal:10-0325970

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy</title>
<author><name sortKey="Cagigi, Alberto" sort="Cagigi, Alberto" uniqKey="Cagigi A" first="Alberto" last="Cagigi">Alberto Cagigi</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Laboratory Medicine, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="Nilsson, Anna" sort="Nilsson, Anna" uniqKey="Nilsson A" first="Anna" last="Nilsson">Anna Nilsson</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Paediatric Infectious Diseases Unit, Department of Women and Child Health, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="Pensieroso, Simone" sort="Pensieroso, Simone" uniqKey="Pensieroso S" first="Simone" last="Pensieroso">Simone Pensieroso</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="Chiodi, Francesca" sort="Chiodi, Francesca" uniqKey="Chiodi F" first="Francesca" last="Chiodi">Francesca Chiodi</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">10-0325970</idno>
<date when="2010">2010</date>
<idno type="stanalyst">PASCAL 10-0325970 INIST</idno>
<idno type="RBID">Pascal:10-0325970</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001228</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000C41</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy</title>
<author><name sortKey="Cagigi, Alberto" sort="Cagigi, Alberto" uniqKey="Cagigi A" first="Alberto" last="Cagigi">Alberto Cagigi</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Laboratory Medicine, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="Nilsson, Anna" sort="Nilsson, Anna" uniqKey="Nilsson A" first="Anna" last="Nilsson">Anna Nilsson</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Paediatric Infectious Diseases Unit, Department of Women and Child Health, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="Pensieroso, Simone" sort="Pensieroso, Simone" uniqKey="Pensieroso S" first="Simone" last="Pensieroso">Simone Pensieroso</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="Chiodi, Francesca" sort="Chiodi, Francesca" uniqKey="Chiodi F" first="Francesca" last="Chiodi">Francesca Chiodi</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Lancet. Infectious diseases : (print)</title>
<title level="j" type="abbreviated">Lancet. Infect.  dis. : (print)</title>
<idno type="ISSN">1473-3099</idno>
<imprint><date when="2010">2010</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Lancet. Infectious diseases : (print)</title>
<title level="j" type="abbreviated">Lancet. Infect.  dis. : (print)</title>
<idno type="ISSN">1473-3099</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>AIDS</term>
<term>Antiviral</term>
<term>Chemotherapy</term>
<term>HIV-1 virus</term>
<term>Immunoprophylaxis</term>
<term>Influenza</term>
<term>Vaccination</term>
<term>β Cell</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>SIDA</term>
<term>Grippe</term>
<term>Immunoprophylaxie</term>
<term>Chimiothérapie</term>
<term>Cellule β</term>
<term>Vaccination</term>
<term>Virus HIV1</term>
<term>Antiviral</term>
<term>Protocole HAART</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Vaccination</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Although HIV-1 infection does not directly target B cells, B-cell numbers are reduced and their function is impaired during HIV infection. Antibody titres against antigens previously encountered through vaccination or natural infection are low in patients with HIV Intrinsic B-cell defects might be involved in the impairment of humoral immunity during early HIV infection. Abnormal T-cell activation and the altered expression of molecules involved in the B-cell homing process cause dysfunctional interaction between T and B cells in the germinal centres of lymphoid tissues, which might impair B-cell responses during HIV infection. Class-switch recombination is also impaired in individuals with HIV. Protective immune responses against T-cell-dependent antigens, including influenza antigens, rely on the production of neutralising antibodies. Impaired B-cell responses during HIV infection could therefore hamper the effectiveness of vaccinations against seasonal influenza or the new pandemic influenza A H1N1 vaccines in individuals with HIV. By maintaining B-cell responses, highly active antiretroviral therapy might improve the efficacy of influenza vaccines in individuals with HIV.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>1473-3099</s0>
</fA01>
<fA03 i2="1"><s0>Lancet. Infect.  dis. : (print)</s0>
</fA03>
<fA05><s2>10</s2>
</fA05>
<fA06><s2>7</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>CAGIGI (Alberto)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>NILSSON (Anna)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>PENSIEROSO (Simone)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>CHIODI (Francesca)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Laboratory Medicine, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>1 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Paediatric Infectious Diseases Unit, Department of Women and Child Health, Karolinska Institutet</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>2 aut.</sZ>
</fA14>
<fA20><s1>499-503</s1>
</fA20>
<fA21><s1>2010</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>27478</s2>
<s5>354000180746180060</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2010 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>66 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>10-0325970</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Lancet. Infectious diseases : (print)</s0>
</fA64>
<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Although HIV-1 infection does not directly target B cells, B-cell numbers are reduced and their function is impaired during HIV infection. Antibody titres against antigens previously encountered through vaccination or natural infection are low in patients with HIV Intrinsic B-cell defects might be involved in the impairment of humoral immunity during early HIV infection. Abnormal T-cell activation and the altered expression of molecules involved in the B-cell homing process cause dysfunctional interaction between T and B cells in the germinal centres of lymphoid tissues, which might impair B-cell responses during HIV infection. Class-switch recombination is also impaired in individuals with HIV. Protective immune responses against T-cell-dependent antigens, including influenza antigens, rely on the production of neutralising antibodies. Impaired B-cell responses during HIV infection could therefore hamper the effectiveness of vaccinations against seasonal influenza or the new pandemic influenza A H1N1 vaccines in individuals with HIV. By maintaining B-cell responses, highly active antiretroviral therapy might improve the efficacy of influenza vaccines in individuals with HIV.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B05C02D</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B05C02C</s0>
</fC02>
<fC02 i1="03" i2="X"><s0>002B06D01</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>SIDA</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>AIDS</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>SIDA</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Grippe</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Influenza</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Gripe</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Immunoprophylaxie</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Immunoprophylaxis</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Inmunoprofilaxia</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Chimiothérapie</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Chemotherapy</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Quimioterapia</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Cellule β</s0>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>β Cell</s0>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Célula β</s0>
<s5>07</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Vaccination</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Vaccination</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Vacunación</s0>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Virus HIV1</s0>
<s2>NW</s2>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>HIV-1 virus</s0>
<s2>NW</s2>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>HIV-1 virus</s0>
<s2>NW</s2>
<s5>10</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Antiviral</s0>
<s5>30</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Antiviral</s0>
<s5>30</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Antiviral</s0>
<s5>30</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Protocole HAART</s0>
<s4>INC</s4>
<s5>86</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Virose</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Viral disease</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Virosis</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Infection</s0>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Infection</s0>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Infección</s0>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Traitement</s0>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Treatment</s0>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Tratamiento</s0>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Virus immunodéficience humaine</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Human immunodeficiency virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Human immunodeficiency virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Immunodéficit</s0>
<s5>37</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Immune deficiency</s0>
<s5>37</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Inmunodeficiencia</s0>
<s5>37</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Immunopathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="09" i2="X" l="ENG"><s0>Immunopathology</s0>
<s5>39</s5>
</fC07>
<fC07 i1="09" i2="X" l="SPA"><s0>Inmunopatología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="10" i2="X" l="FRE"><s0>Prévention</s0>
<s5>40</s5>
</fC07>
<fC07 i1="10" i2="X" l="ENG"><s0>Prevention</s0>
<s5>40</s5>
</fC07>
<fC07 i1="10" i2="X" l="SPA"><s0>Prevención</s0>
<s5>40</s5>
</fC07>
<fN21><s1>207</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/PascalFrancis/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C41 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Curation/biblio.hfd -nk 000C41 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    PandemieGrippaleV1
   |flux=    PascalFrancis
   |étape=   Curation
   |type=    RBID
   |clé=     Pascal:10-0325970
   |texte=   Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy
}}

This area was generated with Dilib version V0.6.34.
Data generation: Wed Jun 10 11:04:28 2020. Site generation: Sun Mar 28 09:10:28 2021

	Serveur d'exploration sur les pandémies grippales
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur les pandémies grippales

Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy

Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri