Impact of Influenza B Lineage-Level Mismatch Between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012
Identifieur interne : 000011 ( PascalFrancis/Corpus ); précédent : 000010; suivant : 000012Impact of Influenza B Lineage-Level Mismatch Between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012
Auteurs : Terho Heikkinen ; Niina Ikonen ; Thedi ZieglerSource :
- Clinical infectious diseases [ 1058-4838 ] ; 2014.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Background. Influenza B virus strains in trivalent influenza vaccines are frequently mismatched to the circulating B strains, but the population-level impact of such mismatches is unknown. We assessed the impact of vaccine mismatch on the epidemiology of influenza B during 12 recent seasonal outbreaks of influenza in Finland. Methods. We analyzed all available nationwide data on virologically confirmed influenza infections in all age groups in Finland between 1 July 1999 and 30 June 2012, with the exclusion of the pandemic season of 2009-2010. We derived data on influenza infections and the circulation of different lineages of B viruses during each season from the Infectious Diseases Register and the National Influenza Center, National Institute for Health and Welfare, Finland. Results. A total of 34 788 cases of influenza were recorded. Influenza A accounted for 74.0% and influenza B for 26.0% of all typed viruses. Throughout the 12 seasons, we estimated that 41.7% (3750 of 8993) of all influenza B infections were caused by viruses representing the other genetic lineage than the one in the vaccine. Altogether, opposite-lineage influenza B viruses accounted for 10.8% of all influenza infections in the population, the proportion being highest (16.8%) in children aged 10-14 years and lowest (2.6%) in persons aged ≥70 years. Conclusions. The population-level impact of lineage-level mismatch between the vaccine and circulating strains of influenza B viruses is substantial, especially among children and adolescents. The results provide strong support for the inclusion of both influenza B lineages in seasonal influenza vaccines.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
| pA |
|
|---|
Format Inist (serveur)
| NO : | PASCAL 15-0013399 INIST |
|---|---|
| ET : | Impact of Influenza B Lineage-Level Mismatch Between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012 |
| AU : | HEIKKINEN (Terho); IKONEN (Niina); ZIEGLER (Thedi) |
| AF : | Department of Pediatrics, University of Turku and Turku University Hospital/Finlande (1 aut.); National Influenza Center, National Institute for Health and Welfare/Helsinki/Finlande (2 aut., 3 aut.) |
| DT : | Publication en série; Niveau analytique |
| SO : | Clinical infectious diseases; ISSN 1058-4838; Coden CIDIEL; Royaume-Uni; Da. 2014; Vol. 59; No. 11; Pp. 1519-1524; Bibl. 25 ref. |
| LA : | Anglais |
| EA : | Background. Influenza B virus strains in trivalent influenza vaccines are frequently mismatched to the circulating B strains, but the population-level impact of such mismatches is unknown. We assessed the impact of vaccine mismatch on the epidemiology of influenza B during 12 recent seasonal outbreaks of influenza in Finland. Methods. We analyzed all available nationwide data on virologically confirmed influenza infections in all age groups in Finland between 1 July 1999 and 30 June 2012, with the exclusion of the pandemic season of 2009-2010. We derived data on influenza infections and the circulation of different lineages of B viruses during each season from the Infectious Diseases Register and the National Influenza Center, National Institute for Health and Welfare, Finland. Results. A total of 34 788 cases of influenza were recorded. Influenza A accounted for 74.0% and influenza B for 26.0% of all typed viruses. Throughout the 12 seasons, we estimated that 41.7% (3750 of 8993) of all influenza B infections were caused by viruses representing the other genetic lineage than the one in the vaccine. Altogether, opposite-lineage influenza B viruses accounted for 10.8% of all influenza infections in the population, the proportion being highest (16.8%) in children aged 10-14 years and lowest (2.6%) in persons aged ≥70 years. Conclusions. The population-level impact of lineage-level mismatch between the vaccine and circulating strains of influenza B viruses is substantial, especially among children and adolescents. The results provide strong support for the inclusion of both influenza B lineages in seasonal influenza vaccines. |
| CC : | 002B05C02C |
| FD : | Grippe B; Immunoprophylaxie; Variation saisonnière; Vaccin; Prévention |
| FG : | Virose; Infection; Epidémiologie |
| ED : | Influenza B; Immunoprophylaxis; Seasonal variation; Vaccine; Prevention |
| EG : | Viral disease; Infection; Epidemiology |
| SD : | Gripe B; Inmunoprofilaxia; Variación estacional; Vacuna; Prevención |
| LO : | INIST-18407.354000503550080020 |
| ID : | 15-0013399 |
Links to Exploration step
Pascal:15-0013399Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Impact of Influenza B Lineage-Level Mismatch Between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012</title><author><name sortKey="Heikkinen, Terho" sort="Heikkinen, Terho" uniqKey="Heikkinen T" first="Terho" last="Heikkinen">Terho Heikkinen</name><affiliation><inist:fA14 i1="01"><s1>Department of Pediatrics, University of Turku and Turku University Hospital</s1><s3>FIN</s3><sZ>1 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Ikonen, Niina" sort="Ikonen, Niina" uniqKey="Ikonen N" first="Niina" last="Ikonen">Niina Ikonen</name><affiliation><inist:fA14 i1="02"><s1>National Influenza Center, National Institute for Health and Welfare</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Ziegler, Thedi" sort="Ziegler, Thedi" uniqKey="Ziegler T" first="Thedi" last="Ziegler">Thedi Ziegler</name><affiliation><inist:fA14 i1="02"><s1>National Influenza Center, National Institute for Health and Welfare</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">15-0013399</idno><date when="2014">2014</date><idno type="stanalyst">PASCAL 15-0013399 INIST</idno><idno type="RBID">Pascal:15-0013399</idno><idno type="wicri:Area/PascalFrancis/Corpus">000011</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Impact of Influenza B Lineage-Level Mismatch Between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012</title><author><name sortKey="Heikkinen, Terho" sort="Heikkinen, Terho" uniqKey="Heikkinen T" first="Terho" last="Heikkinen">Terho Heikkinen</name><affiliation><inist:fA14 i1="01"><s1>Department of Pediatrics, University of Turku and Turku University Hospital</s1><s3>FIN</s3><sZ>1 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Ikonen, Niina" sort="Ikonen, Niina" uniqKey="Ikonen N" first="Niina" last="Ikonen">Niina Ikonen</name><affiliation><inist:fA14 i1="02"><s1>National Influenza Center, National Institute for Health and Welfare</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Ziegler, Thedi" sort="Ziegler, Thedi" uniqKey="Ziegler T" first="Thedi" last="Ziegler">Thedi Ziegler</name><affiliation><inist:fA14 i1="02"><s1>National Influenza Center, National Institute for Health and Welfare</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14></affiliation></author></analytic><series><title level="j" type="main">Clinical infectious diseases</title><title level="j" type="abbreviated">Clin. infect. dis.</title><idno type="ISSN">1058-4838</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Clinical infectious diseases</title><title level="j" type="abbreviated">Clin. infect. dis.</title><idno type="ISSN">1058-4838</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Immunoprophylaxis</term><term>Influenza B</term><term>Prevention</term><term>Seasonal variation</term><term>Vaccine</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Grippe B</term><term>Immunoprophylaxie</term><term>Variation saisonnière</term><term>Vaccin</term><term>Prévention</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background. Influenza B virus strains in trivalent influenza vaccines are frequently mismatched to the circulating B strains, but the population-level impact of such mismatches is unknown. We assessed the impact of vaccine mismatch on the epidemiology of influenza B during 12 recent seasonal outbreaks of influenza in Finland. Methods. We analyzed all available nationwide data on virologically confirmed influenza infections in all age groups in Finland between 1 July 1999 and 30 June 2012, with the exclusion of the pandemic season of 2009-2010. We derived data on influenza infections and the circulation of different lineages of B viruses during each season from the Infectious Diseases Register and the National Influenza Center, National Institute for Health and Welfare, Finland. Results. A total of 34 788 cases of influenza were recorded. Influenza A accounted for 74.0% and influenza B for 26.0% of all typed viruses. Throughout the 12 seasons, we estimated that 41.7% (3750 of 8993) of all influenza B infections were caused by viruses representing the other genetic lineage than the one in the vaccine. Altogether, opposite-lineage influenza B viruses accounted for 10.8% of all influenza infections in the population, the proportion being highest (16.8%) in children aged 10-14 years and lowest (2.6%) in persons aged ≥70 years. Conclusions. The population-level impact of lineage-level mismatch between the vaccine and circulating strains of influenza B viruses is substantial, especially among children and adolescents. The results provide strong support for the inclusion of both influenza B lineages in seasonal influenza vaccines.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>1058-4838</s0></fA01><fA02 i1="01"><s0>CIDIEL</s0></fA02><fA03 i2="1"><s0>Clin. infect. dis.</s0></fA03><fA05><s2>59</s2></fA05><fA06><s2>11</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Impact of Influenza B Lineage-Level Mismatch Between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012</s1></fA08><fA11 i1="01" i2="1"><s1>HEIKKINEN (Terho)</s1></fA11><fA11 i1="02" i2="1"><s1>IKONEN (Niina)</s1></fA11><fA11 i1="03" i2="1"><s1>ZIEGLER (Thedi)</s1></fA11><fA14 i1="01"><s1>Department of Pediatrics, University of Turku and Turku University Hospital</s1><s3>FIN</s3><sZ>1 aut.</sZ></fA14><fA14 i1="02"><s1>National Influenza Center, National Institute for Health and Welfare</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ></fA14><fA20><s1>1519-1524</s1></fA20><fA21><s1>2014</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>18407</s2><s5>354000503550080020</s5></fA43><fA44><s0>0000</s0><s1>© 2015 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>25 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>15-0013399</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Clinical infectious diseases</s0></fA64><fA66 i1="01"><s0>GBR</s0></fA66><fC01 i1="01" l="ENG"><s0>Background. Influenza B virus strains in trivalent influenza vaccines are frequently mismatched to the circulating B strains, but the population-level impact of such mismatches is unknown. We assessed the impact of vaccine mismatch on the epidemiology of influenza B during 12 recent seasonal outbreaks of influenza in Finland. Methods. We analyzed all available nationwide data on virologically confirmed influenza infections in all age groups in Finland between 1 July 1999 and 30 June 2012, with the exclusion of the pandemic season of 2009-2010. We derived data on influenza infections and the circulation of different lineages of B viruses during each season from the Infectious Diseases Register and the National Influenza Center, National Institute for Health and Welfare, Finland. Results. A total of 34 788 cases of influenza were recorded. Influenza A accounted for 74.0% and influenza B for 26.0% of all typed viruses. Throughout the 12 seasons, we estimated that 41.7% (3750 of 8993) of all influenza B infections were caused by viruses representing the other genetic lineage than the one in the vaccine. Altogether, opposite-lineage influenza B viruses accounted for 10.8% of all influenza infections in the population, the proportion being highest (16.8%) in children aged 10-14 years and lowest (2.6%) in persons aged ≥70 years. Conclusions. The population-level impact of lineage-level mismatch between the vaccine and circulating strains of influenza B viruses is substantial, especially among children and adolescents. The results provide strong support for the inclusion of both influenza B lineages in seasonal influenza vaccines.</s0></fC01><fC02 i1="01" i2="X"><s0>002B05C02C</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Grippe B</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Influenza B</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Gripe B</s0><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Immunoprophylaxie</s0><s5>04</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Immunoprophylaxis</s0><s5>04</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Inmunoprofilaxia</s0><s5>04</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Variation saisonnière</s0><s5>07</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Seasonal variation</s0><s5>07</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Variación estacional</s0><s5>07</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Vaccin</s0><s5>08</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Vaccine</s0><s5>08</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Vacuna</s0><s5>08</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Prévention</s0><s5>09</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Prevention</s0><s5>09</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Prevención</s0><s5>09</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Virose</s0></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Viral disease</s0></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Virosis</s0></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Infection</s0></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Infection</s0></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Infección</s0></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Epidémiologie</s0><s5>37</s5></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Epidemiology</s0><s5>37</s5></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Epidemiología</s0><s5>37</s5></fC07><fN21><s1>019</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard><server><NO>PASCAL 15-0013399 INIST</NO><ET>Impact of Influenza B Lineage-Level Mismatch Between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012</ET><AU>HEIKKINEN (Terho); IKONEN (Niina); ZIEGLER (Thedi)</AU><AF>Department of Pediatrics, University of Turku and Turku University Hospital/Finlande (1 aut.); National Influenza Center, National Institute for Health and Welfare/Helsinki/Finlande (2 aut., 3 aut.)</AF><DT>Publication en série; Niveau analytique</DT><SO>Clinical infectious diseases; ISSN 1058-4838; Coden CIDIEL; Royaume-Uni; Da. 2014; Vol. 59; No. 11; Pp. 1519-1524; Bibl. 25 ref.</SO><LA>Anglais</LA><EA>Background. Influenza B virus strains in trivalent influenza vaccines are frequently mismatched to the circulating B strains, but the population-level impact of such mismatches is unknown. We assessed the impact of vaccine mismatch on the epidemiology of influenza B during 12 recent seasonal outbreaks of influenza in Finland. Methods. We analyzed all available nationwide data on virologically confirmed influenza infections in all age groups in Finland between 1 July 1999 and 30 June 2012, with the exclusion of the pandemic season of 2009-2010. We derived data on influenza infections and the circulation of different lineages of B viruses during each season from the Infectious Diseases Register and the National Influenza Center, National Institute for Health and Welfare, Finland. Results. A total of 34 788 cases of influenza were recorded. Influenza A accounted for 74.0% and influenza B for 26.0% of all typed viruses. Throughout the 12 seasons, we estimated that 41.7% (3750 of 8993) of all influenza B infections were caused by viruses representing the other genetic lineage than the one in the vaccine. Altogether, opposite-lineage influenza B viruses accounted for 10.8% of all influenza infections in the population, the proportion being highest (16.8%) in children aged 10-14 years and lowest (2.6%) in persons aged ≥70 years. Conclusions. The population-level impact of lineage-level mismatch between the vaccine and circulating strains of influenza B viruses is substantial, especially among children and adolescents. The results provide strong support for the inclusion of both influenza B lineages in seasonal influenza vaccines.</EA><CC>002B05C02C</CC><FD>Grippe B; Immunoprophylaxie; Variation saisonnière; Vaccin; Prévention</FD><FG>Virose; Infection; Epidémiologie</FG><ED>Influenza B; Immunoprophylaxis; Seasonal variation; Vaccine; Prevention</ED><EG>Viral disease; Infection; Epidemiology</EG><SD>Gripe B; Inmunoprofilaxia; Variación estacional; Vacuna; Prevención</SD><LO>INIST-18407.354000503550080020</LO><ID>15-0013399</ID></server></inist></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/PascalFrancis/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000011 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 000011 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= PandemieGrippaleV1
|flux= PascalFrancis
|étape= Corpus
|type= RBID
|clé= Pascal:15-0013399
|texte= Impact of Influenza B Lineage-Level Mismatch Between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012
}}
| This area was generated with Dilib version V0.6.34. |  |