PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE
Identifieur interne : 002043 ( Ncbi/Merge ); précédent : 002042; suivant : 002044PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE
Auteurs : Svjetlana Grgi ; Elvira Eljuska-Tošev ; Jadranka Nikoli ; Filipa Markoti ; Mladenka Vukojevi ; Helien Bebek-Ivankovi ; Ilija KuzmanSource :
- Acta Clinica Croatica [ 0353-9466 ] ; 2019.
Descripteurs français
- KwdFr :
- Adolescent, Croatie (épidémiologie), Durée du séjour (), Enfant, Enfant d'âge préscolaire, Enfant hospitalisé (), Facteurs de risque, Facteurs sexuels, Femelle, Grippe humaine (diagnostic), Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains, Indice de gravité médicale, Mâle, Pandémies (), Sous-type H1N1 du virus de la grippe A (isolement et purification).
- MESH :
- diagnostic : Grippe humaine.
- isolement et purification : Sous-type H1N1 du virus de la grippe A.
- virologie : Grippe humaine.
- épidémiologie : Croatie, Grippe humaine.
- Adolescent, Durée du séjour, Enfant, Enfant d'âge préscolaire, Enfant hospitalisé, Facteurs de risque, Facteurs sexuels, Femelle, Humains, Indice de gravité médicale, Mâle, Pandémies.
- Wicri :
- geographic : Croatie.
English descriptors
- KwdEn :
- Adolescent, Child, Child, Hospitalized (statistics & numerical data), Child, Preschool, Croatia (epidemiology), Female, Humans, Influenza A Virus, H1N1 Subtype (isolation & purification), Influenza, Human (diagnosis), Influenza, Human (epidemiology), Influenza, Human (virology), Length of Stay (statistics & numerical data), Male, Pandemics (statistics & numerical data), Risk Factors, Severity of Illness Index, Sex Factors.
- MESH :
- geographic , epidemiology : Croatia.
- diagnosis : Influenza, Human.
- epidemiology : Influenza, Human.
- isolation & purification : Influenza A Virus, H1N1 Subtype.
- statistics & numerical data : Child, Hospitalized, Length of Stay, Pandemics.
- virology : Influenza, Human.
- Adolescent, Child, Child, Preschool, Female, Humans, Male, Risk Factors, Severity of Illness Index, Sex Factors.
Abstract
Pandemic influenza A virus (H1N1) 2009 causes a disease that is epidemiologically and clinically not significantly different from seasonal influenza, but there are differences. The aim of the study was to display and compare epidemiological and clinical characteristics of pandemic influenza in children. At Dr. Fran Mihaljević University Hospital for Infectious Diseases in Zagreb, in the first two seasons, the incidence of pandemic influenza virus A (H1N1) in particular was exhaustively analyzed only in patients with laboratory-confirmed pandemic influenza A virus (H1N1) 2009. In hospitalized children with documented influenza pandemic, moderate form of the disease predominated, which ultimately meant shorter hospital stay and fewer complications. Otitis media was the rarest complication in children in both seasons. In conclusion, children younger than 5 years, especially boys, were vulnerable groups for pandemic influenza, presenting as a mild disease with low mortality and few complications. Most of the affected children with influenza did not have important risk factors such as asthma and obesity, highlighted by other authors as significant risk factors.
Url:
DOI: 10.20471/acc.2019.58.03.04
PubMed: 31969753
PubMed Central: 6971810
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PMC:6971810Le document en format XML
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<author><name sortKey="Bebek Ivankovi, Helien" sort="Bebek Ivankovi, Helien" uniqKey="Bebek Ivankovi H" first="Helien" last="Bebek-Ivankovi">Helien Bebek-Ivankovi</name>
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<term>Child</term>
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<term>Child, Preschool</term>
<term>Croatia (epidemiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Influenza A Virus, H1N1 Subtype (isolation & purification)</term>
<term>Influenza, Human (diagnosis)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (virology)</term>
<term>Length of Stay (statistics & numerical data)</term>
<term>Male</term>
<term>Pandemics (statistics & numerical data)</term>
<term>Risk Factors</term>
<term>Severity of Illness Index</term>
<term>Sex Factors</term>
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<term>Croatie (épidémiologie)</term>
<term>Durée du séjour ()</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Enfant hospitalisé ()</term>
<term>Facteurs de risque</term>
<term>Facteurs sexuels</term>
<term>Femelle</term>
<term>Grippe humaine (diagnostic)</term>
<term>Grippe humaine (virologie)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Humains</term>
<term>Indice de gravité médicale</term>
<term>Mâle</term>
<term>Pandémies ()</term>
<term>Sous-type H1N1 du virus de la grippe A (isolement et purification)</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term>
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<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term>
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<term>Length of Stay</term>
<term>Pandemics</term>
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<term>Child</term>
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<term>Male</term>
<term>Risk Factors</term>
<term>Severity of Illness Index</term>
<term>Sex Factors</term>
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<front><div type="abstract" xml:lang="en"><title>SUMMARY</title>
<p>Pandemic influenza A virus (H1N1) 2009 causes a disease that is epidemiologically and clinically not significantly different from seasonal influenza, but there are differences. The aim of the study was to display and compare epidemiological and clinical characteristics of pandemic influenza in children. At Dr. Fran Mihaljević University Hospital for Infectious Diseases in Zagreb, in the first two seasons, the incidence of pandemic influenza virus A (H1N1) in particular was exhaustively analyzed only in patients with laboratory-confirmed pandemic influenza A virus (H1N1) 2009. In hospitalized children with documented influenza pandemic, moderate form of the disease predominated, which ultimately meant shorter hospital stay and fewer complications. Otitis media was the rarest complication in children in both seasons. In conclusion, children younger than 5 years, especially boys, were vulnerable groups for pandemic influenza, presenting as a mild disease with low mortality and few complications. Most of the affected children with influenza did not have important risk factors such as asthma and obesity, highlighted by other authors as significant risk factors.</p>
</div>
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<double pmid="31969753"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE</title>
<author><name sortKey="Grgi, Svjetlana" sort="Grgi, Svjetlana" uniqKey="Grgi S" first="Svjetlana" last="Grgi">Svjetlana Grgi</name>
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<author><name sortKey=" Eljuska Tosev, Elvira" sort=" Eljuska Tosev, Elvira" uniqKey=" Eljuska Tosev E" first="Elvira" last=" Eljuska-Tošev">Elvira Eljuska-Tošev</name>
</author>
<author><name sortKey="Nikoli, Jadranka" sort="Nikoli, Jadranka" uniqKey="Nikoli J" first="Jadranka" last="Nikoli">Jadranka Nikoli</name>
</author>
<author><name sortKey="Markoti, Filipa" sort="Markoti, Filipa" uniqKey="Markoti F" first="Filipa" last="Markoti">Filipa Markoti</name>
</author>
<author><name sortKey="Vukojevi, Mladenka" sort="Vukojevi, Mladenka" uniqKey="Vukojevi M" first="Mladenka" last="Vukojevi">Mladenka Vukojevi</name>
</author>
<author><name sortKey="Bebek Ivankovi, Helien" sort="Bebek Ivankovi, Helien" uniqKey="Bebek Ivankovi H" first="Helien" last="Bebek-Ivankovi">Helien Bebek-Ivankovi</name>
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<author><name sortKey="Kuzman, Ilija" sort="Kuzman, Ilija" uniqKey="Kuzman I" first="Ilija" last="Kuzman">Ilija Kuzman</name>
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</titleStmt>
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<idno type="pmid">31969753</idno>
<idno type="pmc">6971810</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971810</idno>
<idno type="RBID">PMC:6971810</idno>
<idno type="doi">10.20471/acc.2019.58.03.04</idno>
<date when="2019">2019</date>
<idno type="wicri:Area/Pmc/Corpus">000901</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000901</idno>
<idno type="wicri:Area/Pmc/Curation">000901</idno>
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<idno type="wicri:Area/Pmc/Checkpoint">000051</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000051</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE</title>
<author><name sortKey="Grgi, Svjetlana" sort="Grgi, Svjetlana" uniqKey="Grgi S" first="Svjetlana" last="Grgi">Svjetlana Grgi</name>
</author>
<author><name sortKey=" Eljuska Tosev, Elvira" sort=" Eljuska Tosev, Elvira" uniqKey=" Eljuska Tosev E" first="Elvira" last=" Eljuska-Tošev">Elvira Eljuska-Tošev</name>
</author>
<author><name sortKey="Nikoli, Jadranka" sort="Nikoli, Jadranka" uniqKey="Nikoli J" first="Jadranka" last="Nikoli">Jadranka Nikoli</name>
</author>
<author><name sortKey="Markoti, Filipa" sort="Markoti, Filipa" uniqKey="Markoti F" first="Filipa" last="Markoti">Filipa Markoti</name>
</author>
<author><name sortKey="Vukojevi, Mladenka" sort="Vukojevi, Mladenka" uniqKey="Vukojevi M" first="Mladenka" last="Vukojevi">Mladenka Vukojevi</name>
</author>
<author><name sortKey="Bebek Ivankovi, Helien" sort="Bebek Ivankovi, Helien" uniqKey="Bebek Ivankovi H" first="Helien" last="Bebek-Ivankovi">Helien Bebek-Ivankovi</name>
</author>
<author><name sortKey="Kuzman, Ilija" sort="Kuzman, Ilija" uniqKey="Kuzman I" first="Ilija" last="Kuzman">Ilija Kuzman</name>
</author>
</analytic>
<series><title level="j">Acta Clinica Croatica</title>
<idno type="ISSN">0353-9466</idno>
<idno type="eISSN">1333-9451</idno>
<imprint><date when="2019">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
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<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>SUMMARY</title>
<p>Pandemic influenza A virus (H1N1) 2009 causes a disease that is epidemiologically and clinically not significantly different from seasonal influenza, but there are differences. The aim of the study was to display and compare epidemiological and clinical characteristics of pandemic influenza in children. At Dr. Fran Mihaljević University Hospital for Infectious Diseases in Zagreb, in the first two seasons, the incidence of pandemic influenza virus A (H1N1) in particular was exhaustively analyzed only in patients with laboratory-confirmed pandemic influenza A virus (H1N1) 2009. In hospitalized children with documented influenza pandemic, moderate form of the disease predominated, which ultimately meant shorter hospital stay and fewer complications. Otitis media was the rarest complication in children in both seasons. In conclusion, children younger than 5 years, especially boys, were vulnerable groups for pandemic influenza, presenting as a mild disease with low mortality and few complications. Most of the affected children with influenza did not have important risk factors such as asthma and obesity, highlighted by other authors as significant risk factors.</p>
</div>
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</TEI>
</pmc>
<pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE.</title>
<author><name sortKey="Grgi, Svjetlana" sort="Grgi, Svjetlana" uniqKey="Grgi S" first="Svjetlana" last="Grgi">Svjetlana Grgi</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey=" Eljuska Tosev, Elvira" sort=" Eljuska Tosev, Elvira" uniqKey=" Eljuska Tosev E" first="Elvira" last=" Eljuska-Tošev">Elvira Eljuska-Tošev</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nikoli, Jadranka" sort="Nikoli, Jadranka" uniqKey="Nikoli J" first="Jadranka" last="Nikoli">Jadranka Nikoli</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
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</author>
<author><name sortKey="Markoti, Filipa" sort="Markoti, Filipa" uniqKey="Markoti F" first="Filipa" last="Markoti">Filipa Markoti</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
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</author>
<author><name sortKey="Vukojevi, Mladenka" sort="Vukojevi, Mladenka" uniqKey="Vukojevi M" first="Mladenka" last="Vukojevi">Mladenka Vukojevi</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bebek Ivankovi, Helien" sort="Bebek Ivankovi, Helien" uniqKey="Bebek Ivankovi H" first="Helien" last="Bebek-Ivankovi">Helien Bebek-Ivankovi</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kuzman, Ilija" sort="Kuzman, Ilija" uniqKey="Kuzman I" first="Ilija" last="Kuzman">Ilija Kuzman</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
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<date when="2019">2019</date>
<idno type="RBID">pubmed:31969753</idno>
<idno type="pmid">31969753</idno>
<idno type="doi">10.20471/acc.2019.58.03.04</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">PANDEMIC INFLUENZA A (H1N1) 2009 PRESENTING AS A MILD DISEASE IN CHILDREN IN A CROATIAN CLINICAL CENTRE.</title>
<author><name sortKey="Grgi, Svjetlana" sort="Grgi, Svjetlana" uniqKey="Grgi S" first="Svjetlana" last="Grgi">Svjetlana Grgi</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey=" Eljuska Tosev, Elvira" sort=" Eljuska Tosev, Elvira" uniqKey=" Eljuska Tosev E" first="Elvira" last=" Eljuska-Tošev">Elvira Eljuska-Tošev</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nikoli, Jadranka" sort="Nikoli, Jadranka" uniqKey="Nikoli J" first="Jadranka" last="Nikoli">Jadranka Nikoli</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Markoti, Filipa" sort="Markoti, Filipa" uniqKey="Markoti F" first="Filipa" last="Markoti">Filipa Markoti</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vukojevi, Mladenka" sort="Vukojevi, Mladenka" uniqKey="Vukojevi M" first="Mladenka" last="Vukojevi">Mladenka Vukojevi</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bebek Ivankovi, Helien" sort="Bebek Ivankovi, Helien" uniqKey="Bebek Ivankovi H" first="Helien" last="Bebek-Ivankovi">Helien Bebek-Ivankovi</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kuzman, Ilija" sort="Kuzman, Ilija" uniqKey="Kuzman I" first="Ilija" last="Kuzman">Ilija Kuzman</name>
<affiliation wicri:level="1"><nlm:affiliation>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1Department of Infectious Diseases, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina; 3School of Medicine, University of Zagreb, Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Acta clinica Croatica</title>
<idno type="eISSN">1333-9451</idno>
<imprint><date when="2019" type="published">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Child</term>
<term>Child, Hospitalized (statistics & numerical data)</term>
<term>Child, Preschool</term>
<term>Croatia (epidemiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Influenza A Virus, H1N1 Subtype (isolation & purification)</term>
<term>Influenza, Human (diagnosis)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (virology)</term>
<term>Length of Stay (statistics & numerical data)</term>
<term>Male</term>
<term>Pandemics (statistics & numerical data)</term>
<term>Risk Factors</term>
<term>Severity of Illness Index</term>
<term>Sex Factors</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Croatie (épidémiologie)</term>
<term>Durée du séjour ()</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Enfant hospitalisé ()</term>
<term>Facteurs de risque</term>
<term>Facteurs sexuels</term>
<term>Femelle</term>
<term>Grippe humaine (diagnostic)</term>
<term>Grippe humaine (virologie)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Humains</term>
<term>Indice de gravité médicale</term>
<term>Mâle</term>
<term>Pandémies ()</term>
<term>Sous-type H1N1 du virus de la grippe A (isolement et purification)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Croatia</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Sous-type H1N1 du virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Child, Hospitalized</term>
<term>Length of Stay</term>
<term>Pandemics</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Croatie</term>
<term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Risk Factors</term>
<term>Severity of Illness Index</term>
<term>Sex Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Durée du séjour</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Enfant hospitalisé</term>
<term>Facteurs de risque</term>
<term>Facteurs sexuels</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de gravité médicale</term>
<term>Mâle</term>
<term>Pandémies</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Croatie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Pandemic influenza A virus (H1N1) 2009 causes a disease that is epidemiologically and clinically not significantly different from seasonal influenza, but there are differences. The aim of the study was to display and compare epidemiological and clinical characteristics of pandemic influenza in children. At Dr. Fran Mihaljević University Hospital for Infectious Diseases in Zagreb, in the first two seasons, the incidence of pandemic influenza virus A (H1N1) in particular was exhaustively analyzed only in patients with laboratory-confirmed pandemic influenza A virus (H1N1) 2009. In hospitalized children with documented influenza pandemic, moderate form of the disease predominated, which ultimately meant shorter hospital stay and fewer complications. Otitis media was the rarest complication in children in both seasons. In conclusion, children younger than 5 years, especially boys, were vulnerable groups for pandemic influenza, presenting as a mild disease with low mortality and few complications. Most of the affected children with influenza did not have important risk factors such as asthma and obesity, highlighted by other authors as significant risk factors.</div>
</front>
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