PandemieGrippaleV1, Ncbi, Merge, bibRecord, 001F01

Origins of the 1918 Pandemic: Revisiting the Swine "Mixing Vessel" Hypothesis.

Identifieur interne : 001F01 ( Ncbi/Merge ); précédent : 001F00; suivant : 001F02

Origins of the 1918 Pandemic: Revisiting the Swine "Mixing Vessel" Hypothesis.

Auteurs : Martha I. Nelson [États-Unis] ; Michael Worobey [États-Unis]

Source :

American journal of epidemiology [ 1476-6256 ] ; 2018.

RBID : pubmed:30508193

Descripteurs français

KwdFr :
- Animaux, Grippe humaine (histoire), Grippe humaine (mortalité), Grippe humaine (transmission), Grippe humaine (épidémiologie), Histoire du 20ème siècle, Humains, Pandémie de grippe de 1918-1919 (histoire), Pandémie de grippe de 1918-1919 (mortalité), Pandémies (histoire), Suidae (virologie), Virus de la grippe A, Zoonoses (histoire), Zoonoses (mortalité), Zoonoses (transmission), Zoonoses (épidémiologie).
MESH :
- histoire : Grippe humaine, Pandémie de grippe de 1918-1919, Pandémies, Zoonoses.
- mortalité : Grippe humaine, Pandémie de grippe de 1918-1919, Zoonoses.
- virologie : Suidae.
- épidémiologie : Grippe humaine, Zoonoses.
- Animaux, Histoire du 20ème siècle, Humains, Virus de la grippe A.

English descriptors

KwdEn :
- Animals, History, 20th Century, Humans, Influenza A virus, Influenza Pandemic, 1918-1919 (history), Influenza Pandemic, 1918-1919 (mortality), Influenza, Human (epidemiology), Influenza, Human (history), Influenza, Human (mortality), Influenza, Human (transmission), Pandemics (history), Swine (virology), Zoonoses (epidemiology), Zoonoses (history), Zoonoses (mortality), Zoonoses (transmission).
MESH :
- epidemiology : Influenza, Human, Zoonoses.
- history : Influenza Pandemic, 1918-1919, Influenza, Human, Pandemics, Zoonoses.
- mortality : Influenza Pandemic, 1918-1919, Influenza, Human, Zoonoses.
- transmission : Influenza, Human, Zoonoses.
- virology : Swine.
- Animals, History, 20th Century, Humans, Influenza A virus.

Abstract

How influenza A viruses host-jump from animal reservoir species to humans, which can initiate global pandemics, is a central question in pathogen evolution. The zoonotic and spatial origins of the influenza virus associated with the "Spanish flu" pandemic of 1918 have been debated for decades. Outbreaks of respiratory disease in US swine occurred concurrently with disease in humans, raising the possibility that the 1918 virus originated in pigs. Swine also were proposed as "mixing vessel" intermediary hosts between birds and humans during the 1957 Asian and 1968 Hong Kong pandemics. Swine have presented an attractive explanation for how avian viruses overcome the substantial evolutionary barriers presented by different cellular environments in humans and birds. However, key assumptions underpinning the swine mixing-vessel model of pandemic emergence have been challenged in light of new evidence. Increased surveillance in swine has revealed that human-to-swine transmission actually occurs far more frequently than the reverse, and there is no empirical evidence that swine played a role in the emergence of human influenza in 1918, 1957, or 1968. Swine-to-human transmission occurs periodically and can trigger pandemics, as in 2009. But swine are not necessary to mediate the establishment of avian viruses in humans, which invites new perspectives on the evolutionary processes underlying pandemic emergence.

DOI: 10.1093/aje/kwy150
PubMed: 30508193

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Le document en format XML

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<ReferenceList><Reference><Citation>Elife. 2016 Jun 28;5:</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27350259</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Infect Dis. 2014 Feb;14(2):169-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24290840</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1999 Oct;73(10):8851-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10482643</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol J. 2010 Feb 16;7:38</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20158900</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1989 Nov;63(11):4603-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2795713</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2006 Dec;80(23):11887-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16987977</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8107-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24778238</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2002 Nov 15;186(10):1490-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12404167</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Exp Med. 1936 Apr 30;63(5):669-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19870496</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2012 Jun 22;336(6088):1534-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22723413</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1983 Jun;127(2):361-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6868370</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2012 Oct;93(Pt 10):2195-203</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22791604</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Mol Genet Med. 2008 Nov 27;3(1):158-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19565018</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Trends Microbiol. 2015 Mar;23(3):142-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25564096</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11709-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19597152</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1998 Sep;72(9):7367-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9696833</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2014 Apr 10;508(7495):254-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24531761</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>mSphere. 2017 Sep 6;2(5):null</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28904995</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 1931 Feb 20;73(1886):214-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17729823</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Bull World Health Organ. 1981;59(1):75-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6973418</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2009 Jun 25;459(7250):1122-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19516283</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2017 Aug 10;91(17):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28637755</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2000 Dec;74(24):11825-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11090182</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2013 Jul;57 Suppl 1:S4-S11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23794729</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Influenza Other Respir Viruses. 2010 Nov;4(6):327-37</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20958926</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2012 Nov;93(Pt 11):2326-36</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22971819</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2005 Oct 6;437(7060):889-93</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16208372</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
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</country>
<region><li>Arizona</li>
<li>Maryland</li>
</region>
</list>
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	Serveur d'exploration sur les pandémies grippales
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Serveur d'exploration sur les pandémies grippales

Origins of the 1918 Pandemic: Revisiting the Swine "Mixing Vessel" Hypothesis.

Origins of the 1918 Pandemic: Revisiting the Swine "Mixing Vessel" Hypothesis.

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