Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity in intravenous immunoglobulin as a potential therapeutic against emerging influenza viruses.
Identifieur interne : 001870 ( Ncbi/Curation ); précédent : 001869; suivant : 001871Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity in intravenous immunoglobulin as a potential therapeutic against emerging influenza viruses.
Auteurs : Sinthujan Jegaskanda [Australie] ; Kirsten Vandenberg ; Karen L. Laurie [Australie] ; Liyen Loh [Australie] ; Marit Kramski [Australie] ; Wendy R. Winnall [Australie] ; Katherine Kedzierska [Australie] ; Steven Rockman ; Stephen J. Kent [Australie]Source :
- The Journal of infectious diseases [ 1537-6613 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Anticorps antiviraux (immunologie), Anticorps antiviraux (sang), Cellules tueuses naturelles (immunologie), Cytotoxicité à médiation cellulaire dépendante des anticorps (immunologie), Femelle, Glycoprotéine hémagglutinine du virus influenza (immunologie), Grippe humaine (), Grippe humaine (immunologie), Humains, Immunoglobulines par voie veineuse (usage thérapeutique), Jeune adulte, Mâle, Réactions croisées (immunologie), Sous-type H1N1 du virus de la grippe A (immunologie), Sous-type H7N9 du virus de la grippe A (immunologie), Sujet âgé, Sujet âgé de 80 ans ou plus, Tests d'hémagglutination.
- MESH :
- immunologie : Anticorps antiviraux, Cellules tueuses naturelles, Cytotoxicité à médiation cellulaire dépendante des anticorps, Glycoprotéine hémagglutinine du virus influenza, Grippe humaine, Réactions croisées, Sous-type H1N1 du virus de la grippe A, Sous-type H7N9 du virus de la grippe A.
- sang : Anticorps antiviraux.
- usage thérapeutique : Immunoglobulines par voie veineuse.
- Adulte, Adulte d'âge moyen, Femelle, Grippe humaine, Humains, Jeune adulte, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Tests d'hémagglutination.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Antibodies, Viral (blood), Antibodies, Viral (immunology), Antibody-Dependent Cell Cytotoxicity (immunology), Cross Reactions (immunology), Female, Hemagglutination Tests, Hemagglutinin Glycoproteins, Influenza Virus (immunology), Humans, Immunoglobulins, Intravenous (therapeutic use), Influenza A Virus, H1N1 Subtype (immunology), Influenza A Virus, H7N9 Subtype (immunology), Influenza, Human (immunology), Influenza, Human (therapy), Killer Cells, Natural (immunology), Male, Middle Aged, Young Adult.
- MESH :
- chemical , blood : Antibodies, Viral.
- chemical , immunology : Antibodies, Viral, Hemagglutinin Glycoproteins, Influenza Virus.
- immunology : Antibody-Dependent Cell Cytotoxicity, Cross Reactions, Influenza A Virus, H1N1 Subtype, Influenza A Virus, H7N9 Subtype, Influenza, Human, Killer Cells, Natural.
- chemical , therapeutic use : Immunoglobulins, Intravenous.
- therapy : Influenza, Human.
- Adult, Aged, Aged, 80 and over, Female, Hemagglutination Tests, Humans, Male, Middle Aged, Young Adult.
Abstract
Intravenous immunoglobulin (IVIG) is a purified pool of human antibodies from thousands of donors that is used to prevent or treat primary immune deficiency, several infectious diseases, and autoimmune diseases. The antibodies that mediate antibody-dependent cellular cytotoxicity (ADCC) against heterologous influenza strains may be present in IVIG preparations.
DOI: 10.1093/infdis/jiu334
PubMed: 24916185
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Kirsten Vandenberg<affiliation><nlm:affiliation>BioCSL Ltd, Parkville, Victoria.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Microbiology and Immunology, at the Peter Doherty Institute for Infection and Immunity, University of Melbourne BioCSL Ltd, Parkville, Victoria.</nlm:affiliation>
<wicri:noCountry code="subField">Victoria</wicri:noCountry>
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Le document en format XML
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<term>Cellules tueuses naturelles (immunologie)</term>
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<front><div type="abstract" xml:lang="en">Intravenous immunoglobulin (IVIG) is a purified pool of human antibodies from thousands of donors that is used to prevent or treat primary immune deficiency, several infectious diseases, and autoimmune diseases. The antibodies that mediate antibody-dependent cellular cytotoxicity (ADCC) against heterologous influenza strains may be present in IVIG preparations.</div>
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