Perspective of Use of Antiviral Peptides against Influenza Virus
Identifieur interne : 001B01 ( Ncbi/Checkpoint ); précédent : 001B00; suivant : 001B02Perspective of Use of Antiviral Peptides against Influenza Virus
Auteurs : Sylvie Skalickova ; Zbynek Heger [République tchèque] ; Ludmila Krejcova ; Vladimir Pekarik ; Karel Bastl ; Jozef Janda ; Frantisek Kostolansky ; Eva Vareckova ; Ondrej Zitka [République tchèque] ; Vojtech Adam [République tchèque] ; Rene Kizek [République tchèque]Source :
- Viruses [ 1999-4915 ] ; 2015.
Descripteurs français
- KwdFr :
- Animaux, Antiviraux (pharmacologie), Antiviraux (usage thérapeutique), Découverte de médicament (tendances), Essais cliniques comme sujet, Grippe humaine (traitement médicamenteux), Humains, Infections à Orthomyxoviridae (traitement médicamenteux), Modèles animaux de maladie humaine, Orthomyxoviridae (), Orthomyxoviridae (physiologie), Peptides (pharmacologie), Peptides (usage thérapeutique), Pénétration virale (), Réplication virale ().
- MESH :
- pharmacologie : Antiviraux, Peptides.
- physiologie : Orthomyxoviridae.
- tendances : Découverte de médicament.
- traitement médicamenteux : Grippe humaine, Infections à Orthomyxoviridae.
- usage thérapeutique : Antiviraux, Peptides.
- Animaux, Essais cliniques comme sujet, Humains, Modèles animaux de maladie humaine, Orthomyxoviridae, Pénétration virale, Réplication virale.
English descriptors
- KwdEn :
- Animals, Antiviral Agents (pharmacology), Antiviral Agents (therapeutic use), Clinical Trials as Topic, Disease Models, Animal, Drug Discovery (trends), Humans, Influenza, Human (drug therapy), Orthomyxoviridae (drug effects), Orthomyxoviridae (physiology), Orthomyxoviridae Infections (drug therapy), Peptides (pharmacology), Peptides (therapeutic use), Virus Internalization (drug effects), Virus Replication (drug effects).
- MESH :
- chemical , pharmacology : Antiviral Agents, Peptides.
- chemical , therapeutic use : Antiviral Agents, Peptides.
- drug effects : Orthomyxoviridae, Virus Internalization, Virus Replication.
- drug therapy : Influenza, Human, Orthomyxoviridae Infections.
- physiology : Orthomyxoviridae.
- trends : Drug Discovery.
- Animals, Clinical Trials as Topic, Disease Models, Animal, Humans.
Abstract
The threat of a worldwide influenza pandemic has greatly increased over the past decade with the emergence of highly virulent avian influenza strains. The increased frequency of drug-resistant influenza strains against currently available antiviral drugs requires urgent development of new strategies for antiviral therapy, too. The research in the field of therapeutic peptides began to develop extensively in the second half of the 20th century. Since then, the mechanisms of action for several peptides and their antiviral prospect received large attention due to the global threat posed by viruses. Here, we discussed the therapeutic properties of peptides used in influenza treatment. Peptides with antiviral activity against influenza can be divided into three main groups. First, entry blocker peptides such as a Flupep that interact with influenza hemagglutinin, block its binding to host cells and prevent viral fusion. Second, several peptides display virucidal activity, disrupting viral envelopes, e.g., Melittin. Finally, a third set of peptides interacts with the viral polymerase complex and act as viral replication inhibitors such as PB1 derived peptides. Here, we present a review of the current literature describing the antiviral activity, mechanism and future therapeutic potential of these influenza antiviral peptides.
Url:
DOI: 10.3390/v7102883
PubMed: 26492266
PubMed Central: 4632391
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000057
- to stream Pmc, to step Curation: 000057
- to stream Pmc, to step Checkpoint: 000350
- to stream PubMed, to step Corpus: 000588
- to stream PubMed, to step Curation: 000588
- to stream PubMed, to step Checkpoint: 000594
- to stream Ncbi, to step Merge: 001B01
- to stream Ncbi, to step Curation: 001B01
Links to Exploration step
PMC:4632391Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Perspective of Use of Antiviral Peptides against Influenza Virus</title><author><name sortKey="Skalickova, Sylvie" sort="Skalickova, Sylvie" uniqKey="Skalickova S" first="Sylvie" last="Skalickova">Sylvie Skalickova</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation></author><author><name sortKey="Heger, Zbynek" sort="Heger, Zbynek" uniqKey="Heger Z" first="Zbynek" last="Heger">Zbynek Heger</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af2-viruses-07-02883">Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00, Czech Republic</nlm:aff><country xml:lang="fr">République tchèque</country><wicri:regionArea>Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00</wicri:regionArea><wicri:noRegion>Brno CZ-616 00</wicri:noRegion></affiliation></author><author><name sortKey="Krejcova, Ludmila" sort="Krejcova, Ludmila" uniqKey="Krejcova L" first="Ludmila" last="Krejcova">Ludmila Krejcova</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation></author><author><name sortKey="Pekarik, Vladimir" sort="Pekarik, Vladimir" uniqKey="Pekarik V" first="Vladimir" last="Pekarik">Vladimir Pekarik</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation></author><author><name sortKey="Bastl, Karel" sort="Bastl, Karel" uniqKey="Bastl K" first="Karel" last="Bastl">Karel Bastl</name><affiliation><nlm:aff id="af3-viruses-07-02883">Wool and Knitting Research Institute, Brno, Sujanovo namesti 3, Brno CZ-602 00, Czech Republic;<email>bast@vup.cz</email></nlm:aff></affiliation></author><author><name sortKey="Janda, Jozef" sort="Janda, Jozef" uniqKey="Janda J" first="Jozef" last="Janda">Jozef Janda</name><affiliation><nlm:aff id="af4-viruses-07-02883">Laboratory of Tumour Biology, Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, Libechov CZ-277 21, Czech Republic;<email>janda@iapg.cas.cz</email></nlm:aff></affiliation></author><author><name sortKey="Kostolansky, Frantisek" sort="Kostolansky, Frantisek" uniqKey="Kostolansky F" first="Frantisek" last="Kostolansky">Frantisek Kostolansky</name><affiliation><nlm:aff id="af5-viruses-07-02883">Institute of Virology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovak Republic;<email>frantisek.kostolansky@savba.sk</email> (F.K.);<email>viruevar@savba.sk</email> (E.V.)</nlm:aff></affiliation></author><author><name sortKey="Vareckova, Eva" sort="Vareckova, Eva" uniqKey="Vareckova E" first="Eva" last="Vareckova">Eva Vareckova</name><affiliation><nlm:aff id="af5-viruses-07-02883">Institute of Virology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovak Republic;<email>frantisek.kostolansky@savba.sk</email> (F.K.);<email>viruevar@savba.sk</email> (E.V.)</nlm:aff></affiliation></author><author><name sortKey="Zitka, Ondrej" sort="Zitka, Ondrej" uniqKey="Zitka O" first="Ondrej" last="Zitka">Ondrej Zitka</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af2-viruses-07-02883">Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00, Czech Republic</nlm:aff><country xml:lang="fr">République tchèque</country><wicri:regionArea>Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00</wicri:regionArea><wicri:noRegion>Brno CZ-616 00</wicri:noRegion></affiliation></author><author><name sortKey="Adam, Vojtech" sort="Adam, Vojtech" uniqKey="Adam V" first="Vojtech" last="Adam">Vojtech Adam</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af2-viruses-07-02883">Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00, Czech Republic</nlm:aff><country xml:lang="fr">République tchèque</country><wicri:regionArea>Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00</wicri:regionArea><wicri:noRegion>Brno CZ-616 00</wicri:noRegion></affiliation></author><author><name sortKey="Kizek, Rene" sort="Kizek, Rene" uniqKey="Kizek R" first="Rene" last="Kizek">Rene Kizek</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af2-viruses-07-02883">Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00, Czech Republic</nlm:aff><country xml:lang="fr">République tchèque</country><wicri:regionArea>Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00</wicri:regionArea><wicri:noRegion>Brno CZ-616 00</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26492266</idno><idno type="pmc">4632391</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632391</idno><idno type="RBID">PMC:4632391</idno><idno type="doi">10.3390/v7102883</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000057</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000057</idno><idno type="wicri:Area/Pmc/Curation">000057</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000057</idno><idno type="wicri:Area/Pmc/Checkpoint">000350</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000350</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:26492266</idno><idno type="wicri:Area/PubMed/Corpus">000588</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000588</idno><idno type="wicri:Area/PubMed/Curation">000588</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000588</idno><idno type="wicri:Area/PubMed/Checkpoint">000594</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000594</idno><idno type="wicri:Area/Ncbi/Merge">001B01</idno><idno type="wicri:Area/Ncbi/Curation">001B01</idno><idno type="wicri:Area/Ncbi/Checkpoint">001B01</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Perspective of Use of Antiviral Peptides against Influenza Virus</title><author><name sortKey="Skalickova, Sylvie" sort="Skalickova, Sylvie" uniqKey="Skalickova S" first="Sylvie" last="Skalickova">Sylvie Skalickova</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation></author><author><name sortKey="Heger, Zbynek" sort="Heger, Zbynek" uniqKey="Heger Z" first="Zbynek" last="Heger">Zbynek Heger</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af2-viruses-07-02883">Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00, Czech Republic</nlm:aff><country xml:lang="fr">République tchèque</country><wicri:regionArea>Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00</wicri:regionArea><wicri:noRegion>Brno CZ-616 00</wicri:noRegion></affiliation></author><author><name sortKey="Krejcova, Ludmila" sort="Krejcova, Ludmila" uniqKey="Krejcova L" first="Ludmila" last="Krejcova">Ludmila Krejcova</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation></author><author><name sortKey="Pekarik, Vladimir" sort="Pekarik, Vladimir" uniqKey="Pekarik V" first="Vladimir" last="Pekarik">Vladimir Pekarik</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation></author><author><name sortKey="Bastl, Karel" sort="Bastl, Karel" uniqKey="Bastl K" first="Karel" last="Bastl">Karel Bastl</name><affiliation><nlm:aff id="af3-viruses-07-02883">Wool and Knitting Research Institute, Brno, Sujanovo namesti 3, Brno CZ-602 00, Czech Republic;<email>bast@vup.cz</email></nlm:aff></affiliation></author><author><name sortKey="Janda, Jozef" sort="Janda, Jozef" uniqKey="Janda J" first="Jozef" last="Janda">Jozef Janda</name><affiliation><nlm:aff id="af4-viruses-07-02883">Laboratory of Tumour Biology, Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, Libechov CZ-277 21, Czech Republic;<email>janda@iapg.cas.cz</email></nlm:aff></affiliation></author><author><name sortKey="Kostolansky, Frantisek" sort="Kostolansky, Frantisek" uniqKey="Kostolansky F" first="Frantisek" last="Kostolansky">Frantisek Kostolansky</name><affiliation><nlm:aff id="af5-viruses-07-02883">Institute of Virology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovak Republic;<email>frantisek.kostolansky@savba.sk</email> (F.K.);<email>viruevar@savba.sk</email> (E.V.)</nlm:aff></affiliation></author><author><name sortKey="Vareckova, Eva" sort="Vareckova, Eva" uniqKey="Vareckova E" first="Eva" last="Vareckova">Eva Vareckova</name><affiliation><nlm:aff id="af5-viruses-07-02883">Institute of Virology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovak Republic;<email>frantisek.kostolansky@savba.sk</email> (F.K.);<email>viruevar@savba.sk</email> (E.V.)</nlm:aff></affiliation></author><author><name sortKey="Zitka, Ondrej" sort="Zitka, Ondrej" uniqKey="Zitka O" first="Ondrej" last="Zitka">Ondrej Zitka</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af2-viruses-07-02883">Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00, Czech Republic</nlm:aff><country xml:lang="fr">République tchèque</country><wicri:regionArea>Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00</wicri:regionArea><wicri:noRegion>Brno CZ-616 00</wicri:noRegion></affiliation></author><author><name sortKey="Adam, Vojtech" sort="Adam, Vojtech" uniqKey="Adam V" first="Vojtech" last="Adam">Vojtech Adam</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af2-viruses-07-02883">Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00, Czech Republic</nlm:aff><country xml:lang="fr">République tchèque</country><wicri:regionArea>Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00</wicri:regionArea><wicri:noRegion>Brno CZ-616 00</wicri:noRegion></affiliation></author><author><name sortKey="Kizek, Rene" sort="Kizek, Rene" uniqKey="Kizek R" first="Rene" last="Kizek">Rene Kizek</name><affiliation><nlm:aff id="af1-viruses-07-02883">Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic;<email>sylvie.skalickova@gmail.com</email> (S.S.);<email>heger@mendelu.cz</email> (Z.H.);<email>lidakrejcova@seznam.cz</email> (L.K.);<email>pekarik@node.mendelu.cz</email> (V.P.);<email>zitkao@seznam.cz</email> (O.Z.);<email>vojtech.adam@mendelu.cz</email> (V.A.)</nlm:aff></affiliation><affiliation wicri:level="1"><nlm:aff id="af2-viruses-07-02883">Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00, Czech Republic</nlm:aff><country xml:lang="fr">République tchèque</country><wicri:regionArea>Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00</wicri:regionArea><wicri:noRegion>Brno CZ-616 00</wicri:noRegion></affiliation></author></analytic><series><title level="j">Viruses</title><idno type="eISSN">1999-4915</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antiviral Agents (pharmacology)</term><term>Antiviral Agents (therapeutic use)</term><term>Clinical Trials as Topic</term><term>Disease Models, Animal</term><term>Drug Discovery (trends)</term><term>Humans</term><term>Influenza, Human (drug therapy)</term><term>Orthomyxoviridae (drug effects)</term><term>Orthomyxoviridae (physiology)</term><term>Orthomyxoviridae Infections (drug therapy)</term><term>Peptides (pharmacology)</term><term>Peptides (therapeutic use)</term><term>Virus Internalization (drug effects)</term><term>Virus Replication (drug effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Antiviraux (pharmacologie)</term><term>Antiviraux (usage thérapeutique)</term><term>Découverte de médicament (tendances)</term><term>Essais cliniques comme sujet</term><term>Grippe humaine (traitement médicamenteux)</term><term>Humains</term><term>Infections à Orthomyxoviridae (traitement médicamenteux)</term><term>Modèles animaux de maladie humaine</term><term>Orthomyxoviridae ()</term><term>Orthomyxoviridae (physiologie)</term><term>Peptides (pharmacologie)</term><term>Peptides (usage thérapeutique)</term><term>Pénétration virale ()</term><term>Réplication virale ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antiviral Agents</term><term>Peptides</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term><term>Peptides</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Orthomyxoviridae</term><term>Virus Internalization</term><term>Virus Replication</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Influenza, Human</term><term>Orthomyxoviridae Infections</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Antiviraux</term><term>Peptides</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Orthomyxoviridae</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Orthomyxoviridae</term></keywords><keywords scheme="MESH" qualifier="tendances" xml:lang="fr"><term>Découverte de médicament</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Grippe humaine</term><term>Infections à Orthomyxoviridae</term></keywords><keywords scheme="MESH" qualifier="trends" xml:lang="en"><term>Drug Discovery</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term><term>Peptides</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Clinical Trials as Topic</term><term>Disease Models, Animal</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Essais cliniques comme sujet</term><term>Humains</term><term>Modèles animaux de maladie humaine</term><term>Orthomyxoviridae</term><term>Pénétration virale</term><term>Réplication virale</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The threat of a worldwide influenza pandemic has greatly increased over the past decade with the emergence of highly virulent avian influenza strains. The increased frequency of drug-resistant influenza strains against currently available antiviral drugs requires urgent development of new strategies for antiviral therapy, too. The research in the field of therapeutic peptides began to develop extensively in the second half of the 20<sup>th</sup> century. Since then, the mechanisms of action for several peptides and their antiviral prospect received large attention due to the global threat posed by viruses. Here, we discussed the therapeutic properties of peptides used in influenza treatment. Peptides with antiviral activity against influenza can be divided into three main groups. First, entry blocker peptides such as a Flupep that interact with influenza hemagglutinin, block its binding to host cells and prevent viral fusion. Second, several peptides display virucidal activity, disrupting viral envelopes, e.g., Melittin. Finally, a third set of peptides interacts with the viral polymerase complex and act as viral replication inhibitors such as PB1 derived peptides. Here, we present a review of the current literature describing the antiviral activity, mechanism and future therapeutic potential of these influenza antiviral peptides.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Wiesner, J" uniqKey="Wiesner J">J. Wiesner</name></author><author><name sortKey="Vilcinskas, A" uniqKey="Vilcinskas A">A. Vilcinskas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mandal, S M" uniqKey="Mandal S">S.M. Mandal</name></author><author><name sortKey="Silva, O N" uniqKey="Silva O">O.N. Silva</name></author><author><name sortKey="Franco, O L" uniqKey="Franco O">O.L. Franco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nizet, V" uniqKey="Nizet V">V. Nizet</name></author><author><name sortKey="Ohtake, T" uniqKey="Ohtake T">T. Ohtake</name></author><author><name sortKey="Lauth, X" uniqKey="Lauth X">X. Lauth</name></author><author><name sortKey="Trowbridge, J" uniqKey="Trowbridge J">J. Trowbridge</name></author><author><name sortKey="Rudisill, J" uniqKey="Rudisill J">J. Rudisill</name></author><author><name sortKey="Dorschner, R A" uniqKey="Dorschner R">R.A. Dorschner</name></author><author><name sortKey="Pestonjamasp, V" uniqKey="Pestonjamasp V">V. Pestonjamasp</name></author><author><name sortKey="Piraino, J" uniqKey="Piraino J">J. Piraino</name></author><author><name sortKey="Huttner, K" uniqKey="Huttner K">K. Huttner</name></author><author><name sortKey="Gallo, R L" uniqKey="Gallo R">R.L. Gallo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tew, G N" uniqKey="Tew G">G.N. Tew</name></author><author><name sortKey="Clements, D" uniqKey="Clements D">D. Clements</name></author><author><name sortKey="Tang, H Z" uniqKey="Tang H">H.Z. Tang</name></author><author><name sortKey="Arnt, L" uniqKey="Arnt L">L. Arnt</name></author><author><name sortKey="Scott, R W" uniqKey="Scott R">R.W. Scott</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silva, R R" uniqKey="Silva R">R.R. Silva</name></author><author><name sortKey="Avelino, K" uniqKey="Avelino K">K. Avelino</name></author><author><name sortKey="Ribeiro, K L" uniqKey="Ribeiro K">K.L. Ribeiro</name></author><author><name sortKey="Franco, O L" uniqKey="Franco O">O.L. Franco</name></author><author><name sortKey="Oliveira, M D L" uniqKey="Oliveira M">M.D.L. Oliveira</name></author><author><name sortKey="Andrade, C A S" uniqKey="Andrade C">C.A.S. Andrade</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hale, J D" uniqKey="Hale J">J.D. Hale</name></author><author><name sortKey="Hancock, R E" uniqKey="Hancock R">R.E. Hancock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hadley, E B" uniqKey="Hadley E">E.B. Hadley</name></author><author><name sortKey="Hancock, R E W" uniqKey="Hancock R">R.E.W. Hancock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fosgerau, K" uniqKey="Fosgerau K">K. Fosgerau</name></author><author><name sortKey="Hoffmann, T" uniqKey="Hoffmann T">T. Hoffmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sim, I S" uniqKey="Sim I">I.S. Sim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zumla, A" uniqKey="Zumla A">A. Zumla</name></author><author><name sortKey="Memish, Z A" uniqKey="Memish Z">Z.A. Memish</name></author><author><name sortKey="Maeurer, M" uniqKey="Maeurer M">M. Maeurer</name></author><author><name sortKey="Bates, M" uniqKey="Bates M">M. Bates</name></author><author><name sortKey="Mwaba, P" uniqKey="Mwaba P">P. Mwaba</name></author><author><name sortKey="Al Tawfiq, J A" uniqKey="Al Tawfiq J">J.A. Al-Tawfiq</name></author><author><name sortKey="Denning, D W" uniqKey="Denning D">D.W. Denning</name></author><author><name sortKey="Hayden, F G" uniqKey="Hayden F">F.G. Hayden</name></author><author><name sortKey="Hui, D S" uniqKey="Hui D">D.S. Hui</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berkhout, B" uniqKey="Berkhout B">B. Berkhout</name></author><author><name sortKey="Sanders, R W" uniqKey="Sanders R">R.W. Sanders</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wilson, J C" uniqKey="Wilson J">J.C. Wilson</name></author><author><name sortKey="Von Itzstein, M" uniqKey="Von Itzstein M">M. von Itzstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Air, G M" uniqKey="Air G">G.M. Air</name></author><author><name sortKey="Brouillette, W J" uniqKey="Brouillette W">W.J. Brouillette</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krol, E" uniqKey="Krol E">E. Krol</name></author><author><name sortKey="Rychowska, M" uniqKey="Rychowska M">M. Rychowska</name></author><author><name sortKey="Szewczyk, B" uniqKey="Szewczyk B">B. Szewczyk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jitendra, P K" uniqKey="Jitendra P">P.K. Jitendra</name></author><author><name sortKey="Bansal, S" uniqKey="Bansal S">S. Bansal</name></author><author><name sortKey="Banik, A" uniqKey="Banik A">A. Banik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vlieghe, P" uniqKey="Vlieghe P">P. Vlieghe</name></author><author><name sortKey="Lisowski, V" uniqKey="Lisowski V">V. Lisowski</name></author><author><name sortKey="Martinez, J" uniqKey="Martinez J">J. Martinez</name></author><author><name sortKey="Khrestchatisky, M" uniqKey="Khrestchatisky M">M. Khrestchatisky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liderot, K" uniqKey="Liderot K">K. Liderot</name></author><author><name sortKey="Ahl, M" uniqKey="Ahl M">M. Ahl</name></author><author><name sortKey="Ozenci, V" uniqKey="Ozenci V">V. Ozenci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Teixeira, V" uniqKey="Teixeira V">V. Teixeira</name></author><author><name sortKey="Feio, M J" uniqKey="Feio M">M.J. Feio</name></author><author><name sortKey="Bastos, M" uniqKey="Bastos M">M. Bastos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Giangaspero, A" uniqKey="Giangaspero A">A. Giangaspero</name></author><author><name sortKey="Sandri, L" uniqKey="Sandri L">L. Sandri</name></author><author><name sortKey="Tossi, A" uniqKey="Tossi A">A. Tossi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yin, L M" uniqKey="Yin L">L.M. Yin</name></author><author><name sortKey="Edwards, M A" uniqKey="Edwards M">M.A. Edwards</name></author><author><name sortKey="Li, J" uniqKey="Li J">J. Li</name></author><author><name sortKey="Yip, C M" uniqKey="Yip C">C.M. Yip</name></author><author><name sortKey="Deber, C M" uniqKey="Deber C">C.M. Deber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, N" uniqKey="Lee N">N. Lee</name></author><author><name sortKey="Walker, E" uniqKey="Walker E">E. Walker</name></author><author><name sortKey="Egerer, L" uniqKey="Egerer L">L. Egerer</name></author><author><name sortKey="Bunnell, B A" uniqKey="Bunnell B">B.A. Bunnell</name></author><author><name sortKey="Mondal, D" uniqKey="Mondal D">D. Mondal</name></author><author><name sortKey="Von Laer, D" uniqKey="Von Laer D">D. von Laer</name></author><author><name sortKey="Braun, S E" uniqKey="Braun S">S.E. Braun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pessi, A" uniqKey="Pessi A">A. Pessi</name></author><author><name sortKey="Ingallinella, P" uniqKey="Ingallinella P">P. Ingallinella</name></author><author><name sortKey="Bianchi, E" uniqKey="Bianchi E">E. Bianchi</name></author><author><name sortKey="Wang, Y J" uniqKey="Wang Y">Y.J. Wang</name></author><author><name sortKey="Hrin, R" uniqKey="Hrin R">R. Hrin</name></author><author><name sortKey="Veneziano, M" uniqKey="Veneziano M">M. Veneziano</name></author><author><name sortKey="Bonelli, F" uniqKey="Bonelli F">F. Bonelli</name></author><author><name sortKey="Ketas, T" uniqKey="Ketas T">T. Ketas</name></author><author><name sortKey="Moore, J" uniqKey="Moore J">J. Moore</name></author><author><name sortKey="Miller, M" uniqKey="Miller M">M. Miller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abe, K" uniqKey="Abe K">K. Abe</name></author><author><name sortKey="Nozaki, A" uniqKey="Nozaki A">A. Nozaki</name></author><author><name sortKey="Tamura, K" uniqKey="Tamura K">K. Tamura</name></author><author><name sortKey="Ikeda, M" uniqKey="Ikeda M">M. Ikeda</name></author><author><name sortKey="Naka, K" uniqKey="Naka K">K. Naka</name></author><author><name sortKey="Dansako, H" uniqKey="Dansako H">H. Dansako</name></author><author><name sortKey="Hoshino, H" uniqKey="Hoshino H">H. Hoshino</name></author><author><name sortKey="Tanaka, K" uniqKey="Tanaka K">K. Tanaka</name></author><author><name sortKey="Kato, N" uniqKey="Kato N">N. Kato</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jenssen, H" uniqKey="Jenssen H">H. Jenssen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jaishankar, D" uniqKey="Jaishankar D">D. Jaishankar</name></author><author><name sortKey="Yakoub, A M" uniqKey="Yakoub A">A.M. Yakoub</name></author><author><name sortKey="Bogdanov, A" uniqKey="Bogdanov A">A. Bogdanov</name></author><author><name sortKey="Valyi Nagy, T" uniqKey="Valyi Nagy T">T. Valyi-Nagy</name></author><author><name sortKey="Shukla, D" uniqKey="Shukla D">D. Shukla</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albericio, F" uniqKey="Albericio F">F. Albericio</name></author><author><name sortKey="Kruger, H G" uniqKey="Kruger H">H.G. Kruger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="She, R" uniqKey="She R">R. She</name></author><author><name sortKey="Bao, H" uniqKey="Bao H">H. Bao</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y. Zhang</name></author><author><name sortKey="Luo, D" uniqKey="Luo D">D. Luo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pizzorno, A" uniqKey="Pizzorno A">A. Pizzorno</name></author><author><name sortKey="Abed, Y" uniqKey="Abed Y">Y. Abed</name></author><author><name sortKey="Boivin, G" uniqKey="Boivin G">G. Boivin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mikulasova, A" uniqKey="Mikulasova A">A. Mikulasova</name></author><author><name sortKey="Vareckova, E" uniqKey="Vareckova E">E. Vareckova</name></author><author><name sortKey="Fodor, E" uniqKey="Fodor E">E. Fodor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Das, K" uniqKey="Das K">K. Das</name></author><author><name sortKey="Aramini, J M" uniqKey="Aramini J">J.M. Aramini</name></author><author><name sortKey="Ma, L C" uniqKey="Ma L">L.C. Ma</name></author><author><name sortKey="Krug, R M" uniqKey="Krug R">R.M. Krug</name></author><author><name sortKey="Arnold, E" uniqKey="Arnold E">E. Arnold</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brunotte, L" uniqKey="Brunotte L">L. Brunotte</name></author><author><name sortKey="Flies, J" uniqKey="Flies J">J. Flies</name></author><author><name sortKey="Bolte, H" uniqKey="Bolte H">H. Bolte</name></author><author><name sortKey="Reuther, P" uniqKey="Reuther P">P. Reuther</name></author><author><name sortKey="Vreede, F" uniqKey="Vreede F">F. Vreede</name></author><author><name sortKey="Schwemmle, M" uniqKey="Schwemmle M">M. Schwemmle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stubbs, T M" uniqKey="Stubbs T">T.M. Stubbs</name></author><author><name sortKey="Te Velthuis, A J W" uniqKey="Te Velthuis A">A.J.W. te Velthuis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leser, G P" uniqKey="Leser G">G.P. Leser</name></author><author><name sortKey="Lamb, R A" uniqKey="Lamb R">R.A. Lamb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Takeda, M" uniqKey="Takeda M">M. Takeda</name></author><author><name sortKey="Leser, G P" uniqKey="Leser G">G.P. Leser</name></author><author><name sortKey="Russell, C J" uniqKey="Russell C">C.J. Russell</name></author><author><name sortKey="Lamb, R A" uniqKey="Lamb R">R.A. Lamb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ma, K" uniqKey="Ma K">K. Ma</name></author><author><name sortKey="Wang, Y J" uniqKey="Wang Y">Y.J. Wang</name></author><author><name sortKey="Wang, J F" uniqKey="Wang J">J.F. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rossman, J S" uniqKey="Rossman J">J.S. Rossman</name></author><author><name sortKey="Jing, X H" uniqKey="Jing X">X.H. Jing</name></author><author><name sortKey="Leser, G P" uniqKey="Leser G">G.P. Leser</name></author><author><name sortKey="Lamb, R A" uniqKey="Lamb R">R.A. Lamb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, J C" uniqKey="Jones J">J.C. Jones</name></author><author><name sortKey="Turpin, E A" uniqKey="Turpin E">E.A. Turpin</name></author><author><name sortKey="Bultmann, H" uniqKey="Bultmann H">H. Bultmann</name></author><author><name sortKey="Brandt, C R" uniqKey="Brandt C">C.R. Brandt</name></author><author><name sortKey="Schultz Cherry, S" uniqKey="Schultz Cherry S">S. Schultz-Cherry</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, J C" uniqKey="Jones J">J.C. Jones</name></author><author><name sortKey="Settles, E W" uniqKey="Settles E">E.W. Settles</name></author><author><name sortKey="Brandt, C R" uniqKey="Brandt C">C.R. Brandt</name></author><author><name sortKey="Schultz Cherry, S" uniqKey="Schultz Cherry S">S. Schultz-Cherry</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rajik, M" uniqKey="Rajik M">M. Rajik</name></author><author><name sortKey="Jahanshiri, F" uniqKey="Jahanshiri F">F. Jahanshiri</name></author><author><name sortKey="Omar, A R" uniqKey="Omar A">A.R. Omar</name></author><author><name sortKey="Ideris, A" uniqKey="Ideris A">A. Ideris</name></author><author><name sortKey="Hassan, S S" uniqKey="Hassan S">S.S. Hassan</name></author><author><name sortKey="Yusoff, K" uniqKey="Yusoff K">K. Yusoff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nicol, M Q" uniqKey="Nicol M">M.Q. Nicol</name></author><author><name sortKey="Ligertwood, Y" uniqKey="Ligertwood Y">Y. Ligertwood</name></author><author><name sortKey="Bacon, M N" uniqKey="Bacon M">M.N. Bacon</name></author><author><name sortKey="Dutia, B M" uniqKey="Dutia B">B.M. Dutia</name></author><author><name sortKey="Nash, A A" uniqKey="Nash A">A.A. Nash</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Matsubara, T" uniqKey="Matsubara T">T. Matsubara</name></author><author><name sortKey="Onishi, A" uniqKey="Onishi A">A. Onishi</name></author><author><name sortKey="Saito, T" uniqKey="Saito T">T. Saito</name></author><author><name sortKey="Shimada, A" uniqKey="Shimada A">A. Shimada</name></author><author><name sortKey="Inoue, H" uniqKey="Inoue H">H. Inoue</name></author><author><name sortKey="Taki, T" uniqKey="Taki T">T. Taki</name></author><author><name sortKey="Nagata, K" uniqKey="Nagata K">K. Nagata</name></author><author><name sortKey="Okahata, Y" uniqKey="Okahata Y">Y. Okahata</name></author><author><name sortKey="Sato, T" uniqKey="Sato T">T. Sato</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huttl, C" uniqKey="Huttl C">C. Huttl</name></author><author><name sortKey="Hettrich, C" uniqKey="Hettrich C">C. Hettrich</name></author><author><name sortKey="Miller, R" uniqKey="Miller R">R. Miller</name></author><author><name sortKey="Paulke, B R" uniqKey="Paulke B">B.R. Paulke</name></author><author><name sortKey="Henklein, P" uniqKey="Henklein P">P. Henklein</name></author><author><name sortKey="Rawel, H" uniqKey="Rawel H">H. Rawel</name></author><author><name sortKey="Bier, F F" uniqKey="Bier F">F.F. Bier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cederlund, A" uniqKey="Cederlund A">A. Cederlund</name></author><author><name sortKey="Gudmundsson, G H" uniqKey="Gudmundsson G">G.H. Gudmundsson</name></author><author><name sortKey="Agerberth, B" uniqKey="Agerberth B">B. Agerberth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoffmann, J" uniqKey="Hoffmann J">J. Hoffmann</name></author><author><name sortKey="Schneider, C" uniqKey="Schneider C">C. Schneider</name></author><author><name sortKey="Heinbockel, L" uniqKey="Heinbockel L">L. Heinbockel</name></author><author><name sortKey="Brandenburg, K" uniqKey="Brandenburg K">K. Brandenburg</name></author><author><name sortKey="Reimer, R" uniqKey="Reimer R">R. Reimer</name></author><author><name sortKey="Gabriel, G" uniqKey="Gabriel G">G. Gabriel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Doss, M" uniqKey="Doss M">M. Doss</name></author><author><name sortKey="White, M R" uniqKey="White M">M.R. White</name></author><author><name sortKey="Tecle, T" uniqKey="Tecle T">T. Tecle</name></author><author><name sortKey="Gantz, D" uniqKey="Gantz D">D. Gantz</name></author><author><name sortKey="Crouch, E C" uniqKey="Crouch E">E.C. Crouch</name></author><author><name sortKey="Jung, G" uniqKey="Jung G">G. Jung</name></author><author><name sortKey="Ruchala, P" uniqKey="Ruchala P">P. Ruchala</name></author><author><name sortKey="Waring, A J" uniqKey="Waring A">A.J. Waring</name></author><author><name sortKey="Lehrer, R I" uniqKey="Lehrer R">R.I. Lehrer</name></author><author><name sortKey="Hartshorn, K L" uniqKey="Hartshorn K">K.L. Hartshorn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ammendolia, M G" uniqKey="Ammendolia M">M.G. Ammendolia</name></author><author><name sortKey="Agamennone, M" uniqKey="Agamennone M">M. Agamennone</name></author><author><name sortKey="Pietrantoni, A" uniqKey="Pietrantoni A">A. Pietrantoni</name></author><author><name sortKey="Lannutti, F" uniqKey="Lannutti F">F. Lannutti</name></author><author><name sortKey="Siciliano, R A" uniqKey="Siciliano R">R.A. Siciliano</name></author><author><name sortKey="De Giulio, B" uniqKey="De Giulio B">B. de Giulio</name></author><author><name sortKey="Amici, C" uniqKey="Amici C">C. Amici</name></author><author><name sortKey="Superti, F" uniqKey="Superti F">F. Superti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Q L" uniqKey="Li Q">Q.L. Li</name></author><author><name sortKey="Zhao, Z H" uniqKey="Zhao Z">Z.H. Zhao</name></author><author><name sortKey="Zhou, D H" uniqKey="Zhou D">D.H. Zhou</name></author><author><name sortKey="Chen, Y Q" uniqKey="Chen Y">Y.Q. Chen</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author><author><name sortKey="Cao, L Y" uniqKey="Cao L">L.Y. Cao</name></author><author><name sortKey="Yang, J Y" uniqKey="Yang J">J.Y. Yang</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y. Zhang</name></author><author><name sortKey="Shi, W" uniqKey="Shi W">W. Shi</name></author><author><name sortKey="Cao, Z J" uniqKey="Cao Z">Z.J. Cao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tripathi, S" uniqKey="Tripathi S">S. Tripathi</name></author><author><name sortKey="Tecle, T" uniqKey="Tecle T">T. Tecle</name></author><author><name sortKey="Verma, A" uniqKey="Verma A">A. Verma</name></author><author><name sortKey="Crouch, E" uniqKey="Crouch E">E. Crouch</name></author><author><name sortKey="White, M" uniqKey="White M">M. White</name></author><author><name sortKey="Hartshorn, K L" uniqKey="Hartshorn K">K.L. Hartshorn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ghanem, A" uniqKey="Ghanem A">A. Ghanem</name></author><author><name sortKey="Mayer, D" uniqKey="Mayer D">D. Mayer</name></author><author><name sortKey="Chase, G" uniqKey="Chase G">G. Chase</name></author><author><name sortKey="Tegge, W" uniqKey="Tegge W">W. Tegge</name></author><author><name sortKey="Frank, R" uniqKey="Frank R">R. Frank</name></author><author><name sortKey="Kochs, G" uniqKey="Kochs G">G. Kochs</name></author><author><name sortKey="Garcia Sastre, A" uniqKey="Garcia Sastre A">A. Garcia-Sastre</name></author><author><name sortKey="Schwemmle, M" uniqKey="Schwemmle M">M. Schwemmle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chase, G" uniqKey="Chase G">G. Chase</name></author><author><name sortKey="Wunderlich, K" uniqKey="Wunderlich K">K. Wunderlich</name></author><author><name sortKey="Reuther, P" uniqKey="Reuther P">P. Reuther</name></author><author><name sortKey="Schwemmle, M" uniqKey="Schwemmle M">M. Schwemmle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, J" uniqKey="Yang J">J. Yang</name></author><author><name sortKey="Li, M M" uniqKey="Li M">M.M. Li</name></author><author><name sortKey="Shen, X T" uniqKey="Shen X">X.T. Shen</name></author><author><name sortKey="Liu, S W" uniqKey="Liu S">S.W. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wunderlich, K" uniqKey="Wunderlich K">K. Wunderlich</name></author><author><name sortKey="Mayer, D" uniqKey="Mayer D">D. Mayer</name></author><author><name sortKey="Ranadheera, C" uniqKey="Ranadheera C">C. Ranadheera</name></author><author><name sortKey="Holler, A S" uniqKey="Holler A">A.S. Holler</name></author><author><name sortKey="Manz, B" uniqKey="Manz B">B. Manz</name></author><author><name sortKey="Martin, A" uniqKey="Martin A">A. Martin</name></author><author><name sortKey="Chase, G" uniqKey="Chase G">G. Chase</name></author><author><name sortKey="Tegge, W" uniqKey="Tegge W">W. Tegge</name></author><author><name sortKey="Frank, R" uniqKey="Frank R">R. Frank</name></author><author><name sortKey="Kessler, U" uniqKey="Kessler U">U. Kessler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Conti, G" uniqKey="Conti G">G. Conti</name></author><author><name sortKey="Magliani, W" uniqKey="Magliani W">W. Magliani</name></author><author><name sortKey="Conti, S" uniqKey="Conti S">S. Conti</name></author><author><name sortKey="Nencioni, L" uniqKey="Nencioni L">L. Nencioni</name></author><author><name sortKey="Sgarbanti, R" uniqKey="Sgarbanti R">R. Sgarbanti</name></author><author><name sortKey="Palamara, A T" uniqKey="Palamara A">A.T. Palamara</name></author><author><name sortKey="Polonelli, L" uniqKey="Polonelli L">L. Polonelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Salvatore, M" uniqKey="Salvatore M">M. Salvatore</name></author><author><name sortKey="Garcia Sastre, A" uniqKey="Garcia Sastre A">A. Garcia-Sastre</name></author><author><name sortKey="Ruchala, P" uniqKey="Ruchala P">P. Ruchala</name></author><author><name sortKey="Lehrer, R I" uniqKey="Lehrer R">R.I. Lehrer</name></author><author><name sortKey="Chang, T" uniqKey="Chang T">T. Chang</name></author><author><name sortKey="Klotman, M E" uniqKey="Klotman M">M.E. Klotman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Judd, A K" uniqKey="Judd A">A.K. Judd</name></author><author><name sortKey="Sanchez, A" uniqKey="Sanchez A">A. Sanchez</name></author><author><name sortKey="Bucher, D J" uniqKey="Bucher D">D.J. Bucher</name></author><author><name sortKey="Huffman, J H" uniqKey="Huffman J">J.H. Huffman</name></author><author><name sortKey="Bailey, K" uniqKey="Bailey K">K. Bailey</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nasser, E H" uniqKey="Nasser E">E.H. Nasser</name></author><author><name sortKey="Judd, A K" uniqKey="Judd A">A.K. Judd</name></author><author><name sortKey="Sanchez, A" uniqKey="Sanchez A">A. Sanchez</name></author><author><name sortKey="Anastasiou, D" uniqKey="Anastasiou D">D. Anastasiou</name></author><author><name sortKey="Bucher, D J" uniqKey="Bucher D">D.J. Bucher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ahmed, C M" uniqKey="Ahmed C">C.M. Ahmed</name></author><author><name sortKey="Dabelic, R" uniqKey="Dabelic R">R. Dabelic</name></author><author><name sortKey="Waiboci, L W" uniqKey="Waiboci L">L.W. Waiboci</name></author><author><name sortKey="Jager, L D" uniqKey="Jager L">L.D. Jager</name></author><author><name sortKey="Heron, L L" uniqKey="Heron L">L.L. Heron</name></author><author><name sortKey="Johnson, H M" uniqKey="Johnson H">H.M. Johnson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chang, Y P" uniqKey="Chang Y">Y.P. Chang</name></author><author><name sortKey="Chu, Y H" uniqKey="Chu Y">Y.H. Chu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Udugamasooriya, D G" uniqKey="Udugamasooriya D">D.G. Udugamasooriya</name></author><author><name sortKey="Spaller, M R" uniqKey="Spaller M">M.R. Spaller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, W" uniqKey="Wang W">W. Wang</name></author><author><name sortKey="Cole, A M" uniqKey="Cole A">A.M. Cole</name></author><author><name sortKey="Hong, T" uniqKey="Hong T">T. Hong</name></author><author><name sortKey="Waring, A J" uniqKey="Waring A">A.J. Waring</name></author><author><name sortKey="Lehrer, R I" uniqKey="Lehrer R">R.I. Lehrer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Doss, M" uniqKey="Doss M">M. Doss</name></author><author><name sortKey="White, M R" uniqKey="White M">M.R. White</name></author><author><name sortKey="Tecle, T" uniqKey="Tecle T">T. Tecle</name></author><author><name sortKey="Hartshorn, K L" uniqKey="Hartshorn K">K.L. Hartshorn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gutsmann, T" uniqKey="Gutsmann T">T. Gutsmann</name></author><author><name sortKey="Razquin Olazaran, I" uniqKey="Razquin Olazaran I">I. Razquin-Olazaran</name></author><author><name sortKey="Kowalski, I" uniqKey="Kowalski I">I. Kowalski</name></author><author><name sortKey="Kaconis, Y" uniqKey="Kaconis Y">Y. Kaconis</name></author><author><name sortKey="Howe, J" uniqKey="Howe J">J. Howe</name></author><author><name sortKey="Bartels, R" uniqKey="Bartels R">R. Bartels</name></author><author><name sortKey="Hornef, M" uniqKey="Hornef M">M. Hornef</name></author><author><name sortKey="Schurholz, T" uniqKey="Schurholz T">T. Schurholz</name></author><author><name sortKey="Rossle, M" uniqKey="Rossle M">M. Rossle</name></author><author><name sortKey="Sanchez Gomez, S" uniqKey="Sanchez Gomez S">S. Sanchez-Gomez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krepstakies, M" uniqKey="Krepstakies M">M. Krepstakies</name></author><author><name sortKey="Lucifora, J" uniqKey="Lucifora J">J. Lucifora</name></author><author><name sortKey="Nagel, C H" uniqKey="Nagel C">C.H. Nagel</name></author><author><name sortKey="Zeisel, M B" uniqKey="Zeisel M">M.B. Zeisel</name></author><author><name sortKey="Holstermann, B" uniqKey="Holstermann B">B. Holstermann</name></author><author><name sortKey="Hohenberg, H" uniqKey="Hohenberg H">H. Hohenberg</name></author><author><name sortKey="Kowalski, I" uniqKey="Kowalski I">I. Kowalski</name></author><author><name sortKey="Gutsmann, T" uniqKey="Gutsmann T">T. Gutsmann</name></author><author><name sortKey="Baumert, T F" uniqKey="Baumert T">T.F. Baumert</name></author><author><name sortKey="Brandenburg, K" uniqKey="Brandenburg K">K. Brandenburg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Needham, B D" uniqKey="Needham B">B.D. Needham</name></author><author><name sortKey="Trent, M S" uniqKey="Trent M">M.S. Trent</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Anaya Lopez, J L" uniqKey="Anaya Lopez J">J.L. Anaya-Lopez</name></author><author><name sortKey="Lopez Meza, J E" uniqKey="Lopez Meza J">J.E. Lopez-Meza</name></author><author><name sortKey="Ochoa Zarzosa, A" uniqKey="Ochoa Zarzosa A">A. Ochoa-Zarzosa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mercer, D K" uniqKey="Mercer D">D.K. Mercer</name></author><author><name sortKey="O Eil, D A" uniqKey="O Eil D">D.A. O’Neil</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marcos, J F" uniqKey="Marcos J">J.F. Marcos</name></author><author><name sortKey="Gandia, M" uniqKey="Gandia M">M. Gandia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rajendran, L" uniqKey="Rajendran L">L. Rajendran</name></author><author><name sortKey="Knoelker, H J" uniqKey="Knoelker H">H.-J. Knoelker</name></author><author><name sortKey="Simons, K" uniqKey="Simons K">K. Simons</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Choi, K Y G" uniqKey="Choi K">K.-Y.G. Choi</name></author><author><name sortKey="Mookherjee, N" uniqKey="Mookherjee N">N. Mookherjee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barlow, P G" uniqKey="Barlow P">P.G. Barlow</name></author><author><name sortKey="Svoboda, P" uniqKey="Svoboda P">P. Svoboda</name></author><author><name sortKey="Mackellar, A" uniqKey="Mackellar A">A. Mackellar</name></author><author><name sortKey="Nash, A A" uniqKey="Nash A">A.A. Nash</name></author><author><name sortKey="York, I A" uniqKey="York I">I.A. York</name></author><author><name sortKey="Pohl, J" uniqKey="Pohl J">J. Pohl</name></author><author><name sortKey="Davidson, D J" uniqKey="Davidson D">D.J. Davidson</name></author><author><name sortKey="Donis, R O" uniqKey="Donis R">R.O. Donis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dean, R E" uniqKey="Dean R">R.E. Dean</name></author><author><name sortKey="O Rien, L M" uniqKey="O Rien L">L.M. O’Brien</name></author><author><name sortKey="Thwaite, J E" uniqKey="Thwaite J">J.E. Thwaite</name></author><author><name sortKey="Fox, M A" uniqKey="Fox M">M.A. Fox</name></author><author><name sortKey="Atkins, H" uniqKey="Atkins H">H. Atkins</name></author><author><name sortKey="Ulaeto, D O" uniqKey="Ulaeto D">D.O. Ulaeto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pietrantoni, A" uniqKey="Pietrantoni A">A. Pietrantoni</name></author><author><name sortKey="Di Biase, A M" uniqKey="Di Biase A">A.M. Di Biase</name></author><author><name sortKey="Tinari, A" uniqKey="Tinari A">A. Tinari</name></author><author><name sortKey="Marchetti, M" uniqKey="Marchetti M">M. Marchetti</name></author><author><name sortKey="Valenti, P" uniqKey="Valenti P">P. Valenti</name></author><author><name sortKey="Seganti, L" uniqKey="Seganti L">L. Seganti</name></author><author><name sortKey="Superti, F" uniqKey="Superti F">F. Superti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pietrantoni, A" uniqKey="Pietrantoni A">A. Pietrantoni</name></author><author><name sortKey="Dofrelli, E" uniqKey="Dofrelli E">E. Dofrelli</name></author><author><name sortKey="Tinari, A" uniqKey="Tinari A">A. Tinari</name></author><author><name sortKey="Ammendolia, M G" uniqKey="Ammendolia M">M.G. Ammendolia</name></author><author><name sortKey="Puzelli, S" uniqKey="Puzelli S">S. Puzelli</name></author><author><name sortKey="Fabiani, C" uniqKey="Fabiani C">C. Fabiani</name></author><author><name sortKey="Donatelli, I" uniqKey="Donatelli I">I. Donatelli</name></author><author><name sortKey="Superti, F" uniqKey="Superti F">F. Superti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Balcao, V M" uniqKey="Balcao V">V.M. Balcao</name></author><author><name sortKey="Costa, C I" uniqKey="Costa C">C.I. Costa</name></author><author><name sortKey="Matos, C M" uniqKey="Matos C">C.M. Matos</name></author><author><name sortKey="Moutinho, C G" uniqKey="Moutinho C">C.G. Moutinho</name></author><author><name sortKey="Amorim, M" uniqKey="Amorim M">M. Amorim</name></author><author><name sortKey="Pintado, M E" uniqKey="Pintado M">M.E. Pintado</name></author><author><name sortKey="Gomes, A P" uniqKey="Gomes A">A.P. Gomes</name></author><author><name sortKey="Vila, M M" uniqKey="Vila M">M.M. Vila</name></author><author><name sortKey="Teixeira, J A" uniqKey="Teixeira J">J.A. Teixeira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bibi, S" uniqKey="Bibi S">S. Bibi</name></author><author><name sortKey="Lattmann, E" uniqKey="Lattmann E">E. Lattmann</name></author><author><name sortKey="Mohammed, A R" uniqKey="Mohammed A">A.R. Mohammed</name></author><author><name sortKey="Perrie, Y" uniqKey="Perrie Y">Y. Perrie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raghuraman, H" uniqKey="Raghuraman H">H. Raghuraman</name></author><author><name sortKey="Chattopadhyay, A" uniqKey="Chattopadhyay A">A. Chattopadhyay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, M T" uniqKey="Lee M">M.T. Lee</name></author><author><name sortKey="Hung, W C" uniqKey="Hung W">W.C. Hung</name></author><author><name sortKey="Chen, F Y" uniqKey="Chen F">F.Y. Chen</name></author><author><name sortKey="Huang, H W" uniqKey="Huang H">H.W. Huang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ladokhin, A S" uniqKey="Ladokhin A">A.S. Ladokhin</name></author><author><name sortKey="White, S H" uniqKey="White S">S.H. White</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, N Z" uniqKey="Zhang N">N.Z. Zhang</name></author><author><name sortKey="Qi, J X" uniqKey="Qi J">J.X. Qi</name></author><author><name sortKey="Feng, S J" uniqKey="Feng S">S.J. Feng</name></author><author><name sortKey="Gao, F" uniqKey="Gao F">F. Gao</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J. Liu</name></author><author><name sortKey="Pan, X C" uniqKey="Pan X">X.C. Pan</name></author><author><name sortKey="Chen, R" uniqKey="Chen R">R. Chen</name></author><author><name sortKey="Li, Q R" uniqKey="Li Q">Q.R. Li</name></author><author><name sortKey="Chen, Z S" uniqKey="Chen Z">Z.S. Chen</name></author><author><name sortKey="Li, X Y" uniqKey="Li X">X.Y. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gordon Grossman, M" uniqKey="Gordon Grossman M">M. Gordon-Grossman</name></author><author><name sortKey="Zimmermann, H" uniqKey="Zimmermann H">H. Zimmermann</name></author><author><name sortKey="Wolf, S G" uniqKey="Wolf S">S.G. Wolf</name></author><author><name sortKey="Shai, Y" uniqKey="Shai Y">Y. Shai</name></author><author><name sortKey="Goldfarb, D" uniqKey="Goldfarb D">D. Goldfarb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gordon Grossman, M" uniqKey="Gordon Grossman M">M. Gordon-Grossman</name></author><author><name sortKey="Gofman, Y" uniqKey="Gofman Y">Y. Gofman</name></author><author><name sortKey="Zimmermann, H" uniqKey="Zimmermann H">H. Zimmermann</name></author><author><name sortKey="Frydman, V" uniqKey="Frydman V">V. Frydman</name></author><author><name sortKey="Shai, Y" uniqKey="Shai Y">Y. Shai</name></author><author><name sortKey="Ben Tal, N" uniqKey="Ben Tal N">N. Ben-Tal</name></author><author><name sortKey="Goldfarb, D" uniqKey="Goldfarb D">D. Goldfarb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oren, Z" uniqKey="Oren Z">Z. Oren</name></author><author><name sortKey="Shai, Y" uniqKey="Shai Y">Y. Shai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benachir, T" uniqKey="Benachir T">T. Benachir</name></author><author><name sortKey="Lafleur, M" uniqKey="Lafleur M">M. Lafleur</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, N Y" uniqKey="Lu N">N.Y. Lu</name></author><author><name sortKey="Yang, K" uniqKey="Yang K">K. Yang</name></author><author><name sortKey="Li, J L" uniqKey="Li J">J.L. Li</name></author><author><name sortKey="Yuan, B" uniqKey="Yuan B">B. Yuan</name></author><author><name sortKey="Ma, Y Q" uniqKey="Ma Y">Y.Q. Ma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, W Y" uniqKey="Li W">W.Y. Li</name></author><author><name sortKey="Yang, X F" uniqKey="Yang X">X.F. Yang</name></author><author><name sortKey="Jiang, Y" uniqKey="Jiang Y">Y. Jiang</name></author><author><name sortKey="Wang, B N" uniqKey="Wang B">B.N. Wang</name></author><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y. Yang</name></author><author><name sortKey="Jiang, Z H" uniqKey="Jiang Z">Z.H. Jiang</name></author><author><name sortKey="Li, M Y" uniqKey="Li M">M.Y. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huet, S" uniqKey="Huet S">S. Huet</name></author><author><name sortKey="Avilov, S V" uniqKey="Avilov S">S.V. Avilov</name></author><author><name sortKey="Ferbitz, L" uniqKey="Ferbitz L">L. Ferbitz</name></author><author><name sortKey="Daigle, N" uniqKey="Daigle N">N. Daigle</name></author><author><name sortKey="Cusack, S" uniqKey="Cusack S">S. Cusack</name></author><author><name sortKey="Ellenberg, J" uniqKey="Ellenberg J">J. Ellenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Manz, B" uniqKey="Manz B">B. Manz</name></author><author><name sortKey="Gotz, V" uniqKey="Gotz V">V. Gotz</name></author><author><name sortKey="Wunderlich, K" uniqKey="Wunderlich K">K. Wunderlich</name></author><author><name sortKey="Eisel, J" uniqKey="Eisel J">J. Eisel</name></author><author><name sortKey="Kirchmair, J" uniqKey="Kirchmair J">J. Kirchmair</name></author><author><name sortKey="Stech, J" uniqKey="Stech J">J. Stech</name></author><author><name sortKey="Stech, O" uniqKey="Stech O">O. Stech</name></author><author><name sortKey="Chase, G" uniqKey="Chase G">G. Chase</name></author><author><name sortKey="Frank, R" uniqKey="Frank R">R. Frank</name></author><author><name sortKey="Schwemmle, M" uniqKey="Schwemmle M">M. Schwemmle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ruigrok, R W H" uniqKey="Ruigrok R">R.W.H. Ruigrok</name></author><author><name sortKey="Crepin, T" uniqKey="Crepin T">T. Crepin</name></author><author><name sortKey="Hart, D J" uniqKey="Hart D">D.J. Hart</name></author><author><name sortKey="Cusack, S" uniqKey="Cusack S">S. Cusack</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Engler, A C" uniqKey="Engler A">A.C. Engler</name></author><author><name sortKey="Shukla, A" uniqKey="Shukla A">A. Shukla</name></author><author><name sortKey="Puranam, S" uniqKey="Puranam S">S. Puranam</name></author><author><name sortKey="Buss, H G" uniqKey="Buss H">H.G. Buss</name></author><author><name sortKey="Jreige, N" uniqKey="Jreige N">N. Jreige</name></author><author><name sortKey="Hammond, P T" uniqKey="Hammond P">P.T. Hammond</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ma, Q Q" uniqKey="Ma Q">Q.Q. Ma</name></author><author><name sortKey="Shan, A S" uniqKey="Shan A">A.S. Shan</name></author><author><name sortKey="Dong, N" uniqKey="Dong N">N. Dong</name></author><author><name sortKey="Gu, Y" uniqKey="Gu Y">Y. Gu</name></author><author><name sortKey="Sun, W Y" uniqKey="Sun W">W.Y. Sun</name></author><author><name sortKey="Hu, W N" uniqKey="Hu W">W.N. Hu</name></author><author><name sortKey="Feng, X J" uniqKey="Feng X">X.J. Feng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fechter, P" uniqKey="Fechter P">P. Fechter</name></author><author><name sortKey="Mingay, L" uniqKey="Mingay L">L. Mingay</name></author><author><name sortKey="Sharps, J" uniqKey="Sharps J">J. Sharps</name></author><author><name sortKey="Chambers, A" uniqKey="Chambers A">A. Chambers</name></author><author><name sortKey="Fodor, E" uniqKey="Fodor E">E. Fodor</name></author><author><name sortKey="Brownlee, G G" uniqKey="Brownlee G">G.G. Brownlee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dias, A" uniqKey="Dias A">A. Dias</name></author><author><name sortKey="Bouvier, D" uniqKey="Bouvier D">D. Bouvier</name></author><author><name sortKey="Crepin, T" uniqKey="Crepin T">T. Crepin</name></author><author><name sortKey="Mccarthy, A A" uniqKey="Mccarthy A">A.A. McCarthy</name></author><author><name sortKey="Hart, D J" uniqKey="Hart D">D.J. Hart</name></author><author><name sortKey="Baudin, F" uniqKey="Baudin F">F. Baudin</name></author><author><name sortKey="Cusack, S" uniqKey="Cusack S">S. Cusack</name></author><author><name sortKey="Ruigrok, R W H" uniqKey="Ruigrok R">R.W.H. Ruigrok</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuan, P W" uniqKey="Yuan P">P.W. Yuan</name></author><author><name sortKey="Bartlam, M" uniqKey="Bartlam M">M. Bartlam</name></author><author><name sortKey="Lou, Z Y" uniqKey="Lou Z">Z.Y. Lou</name></author><author><name sortKey="Chen, S D" uniqKey="Chen S">S.D. Chen</name></author><author><name sortKey="Zhou, J" uniqKey="Zhou J">J. Zhou</name></author><author><name sortKey="He, X J" uniqKey="He X">X.J. He</name></author><author><name sortKey="Lv, Z Y" uniqKey="Lv Z">Z.Y. Lv</name></author><author><name sortKey="Ge, R W" uniqKey="Ge R">R.W. Ge</name></author><author><name sortKey="Li, X M" uniqKey="Li X">X.M. Li</name></author><author><name sortKey="Deng, T" uniqKey="Deng T">T. Deng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhu, X Y" uniqKey="Zhu X">X.Y. Zhu</name></author><author><name sortKey="Yu, W L" uniqKey="Yu W">W.L. Yu</name></author><author><name sortKey="Mcbride, R" uniqKey="Mcbride R">R. McBride</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Chen, L M" uniqKey="Chen L">L.M. Chen</name></author><author><name sortKey="Donis, R O" uniqKey="Donis R">R.O. Donis</name></author><author><name sortKey="Tong, S X" uniqKey="Tong S">S.X. Tong</name></author><author><name sortKey="Paulson, J C" uniqKey="Paulson J">J.C. Paulson</name></author><author><name sortKey="Wilson, I A" uniqKey="Wilson I">I.A. Wilson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stephens, C" uniqKey="Stephens C">C. Stephens</name></author><author><name sortKey="Kazan, K" uniqKey="Kazan K">K. Kazan</name></author><author><name sortKey="Goulter, K C" uniqKey="Goulter K">K.C. Goulter</name></author><author><name sortKey="Maclean, D J" uniqKey="Maclean D">D.J. Maclean</name></author><author><name sortKey="Manners, J M" uniqKey="Manners J">J.M. Manners</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wilson, S S" uniqKey="Wilson S">S.S. Wilson</name></author><author><name sortKey="Wiens, M E" uniqKey="Wiens M">M.E. Wiens</name></author><author><name sortKey="Smith, J G" uniqKey="Smith J">J.G. Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shah, R" uniqKey="Shah R">R. Shah</name></author><author><name sortKey="Chang, T L" uniqKey="Chang T">T.L. Chang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mohan, T" uniqKey="Mohan T">T. Mohan</name></author><author><name sortKey="Sharma, C" uniqKey="Sharma C">C. Sharma</name></author><author><name sortKey="Bhat, A A" uniqKey="Bhat A">A.A. Bhat</name></author><author><name sortKey="Rao, D N" uniqKey="Rao D">D.N. Rao</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République tchèque</li></country></list><tree><noCountry><name sortKey="Bastl, Karel" sort="Bastl, Karel" uniqKey="Bastl K" first="Karel" last="Bastl">Karel Bastl</name><name sortKey="Janda, Jozef" sort="Janda, Jozef" uniqKey="Janda J" first="Jozef" last="Janda">Jozef Janda</name><name sortKey="Kostolansky, Frantisek" sort="Kostolansky, Frantisek" uniqKey="Kostolansky F" first="Frantisek" last="Kostolansky">Frantisek Kostolansky</name><name sortKey="Krejcova, Ludmila" sort="Krejcova, Ludmila" uniqKey="Krejcova L" first="Ludmila" last="Krejcova">Ludmila Krejcova</name><name sortKey="Pekarik, Vladimir" sort="Pekarik, Vladimir" uniqKey="Pekarik V" first="Vladimir" last="Pekarik">Vladimir Pekarik</name><name sortKey="Skalickova, Sylvie" sort="Skalickova, Sylvie" uniqKey="Skalickova S" first="Sylvie" last="Skalickova">Sylvie Skalickova</name><name sortKey="Vareckova, Eva" sort="Vareckova, Eva" uniqKey="Vareckova E" first="Eva" last="Vareckova">Eva Vareckova</name></noCountry><country name="République tchèque"><noRegion><name sortKey="Heger, Zbynek" sort="Heger, Zbynek" uniqKey="Heger Z" first="Zbynek" last="Heger">Zbynek Heger</name></noRegion><name sortKey="Adam, Vojtech" sort="Adam, Vojtech" uniqKey="Adam V" first="Vojtech" last="Adam">Vojtech Adam</name><name sortKey="Kizek, Rene" sort="Kizek, Rene" uniqKey="Kizek R" first="Rene" last="Kizek">Rene Kizek</name><name sortKey="Zitka, Ondrej" sort="Zitka, Ondrej" uniqKey="Zitka O" first="Ondrej" last="Zitka">Ondrej Zitka</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001B01 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 001B01 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= PandemieGrippaleV1
|flux= Ncbi
|étape= Checkpoint
|type= RBID
|clé= PMC:4632391
|texte= Perspective of Use of Antiviral Peptides against Influenza Virus
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:26492266" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a PandemieGrippaleV1
| This area was generated with Dilib version V0.6.34. |  |