PandemieGrippaleV1, Main, Exploration, bibRecordById, Pascal:12-0260908

Household Transmission of 2009 Pandemic Influenza A(H1N1): A Systematic Review and Meta-analysis

Identifieur interne : 002090 ( Main/Exploration ); précédent : 002089; suivant : 002091

Household Transmission of 2009 Pandemic Influenza A(H1N1): A Systematic Review and Meta-analysis

Auteurs : Lincoln L. H. Lau [République populaire de Chine] ; Hiroshi Nishiura [République populaire de Chine, Japon] ; Heath Kelly [Australie] ; Dennis K. M. Ip [République populaire de Chine] ; Gabriel M. Leung [République populaire de Chine] ; Benjamin J. Cowling [République populaire de Chine]

Source :

Epidemiology : (Cambridge, Mass.) [ 1044-3983 ] ; 2012.

RBID : Pascal:12-0260908

Descripteurs français

Pascal (Inist)
- Ménage, Transmission, 2009, Santé publique, Revue systématique, Métaanalyse, Epidémiologie, Pandémie, Grippe H1N1, Virus grippal A(H1N1).
Wicri :
- topic : Ménage, Santé publique.

English descriptors

KwdEn :
- 2009, Epidemiology, H1N1 influenza, Household, Influenza A (H1N1), Metaanalysis, Public health, Systematic review, Transmission.

Abstract

Background: During the 2009 influenza A (H1N1) pandemic, household transmission studies were implemented to better understand the characteristics of the transmission of the novel virus in a confined setting. Methods: We conducted a systematic review and meta-analysis to assess and summarize the findings of these studies. We identified 27 articles, around half of which reported studies conducted in May and June 2009. Results: In 13 of the 27 studies (48%) that collected respiratory specimens from household contacts, point estimates of the risk of secondary infection ranged from 3% to 38%, with substantial heterogeneity. Meta-regression analyses revealed that a part of the heterogeneity reflected varying case ascertainment and study designs. The estimates of symptomatic secondary infection risk, based on 20 studies identifying febrile acute respiratory illness among household contacts, also showed substantial variability, with point estimates ranging from 4% to 37%. Conclusions: Transmission of the 2009 pandemic virus in households appeared to vary among countries and settings, with differences in estimates of the secondary infection risk also partly due to differences in study designs.

Affiliations:

Australie, Japon, République populaire de Chine

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to stream Main, to step Merge: 002149
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Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>2009</term>
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<term>Metaanalysis</term>
<term>Public health</term>
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<front><div type="abstract" xml:lang="en">Background: During the 2009 influenza A (H1N1) pandemic, household transmission studies were implemented to better understand the characteristics of the transmission of the novel virus in a confined setting. Methods: We conducted a systematic review and meta-analysis to assess and summarize the findings of these studies. We identified 27 articles, around half of which reported studies conducted in May and June 2009. Results: In 13 of the 27 studies (48%) that collected respiratory specimens from household contacts, point estimates of the risk of secondary infection ranged from 3% to 38%, with substantial heterogeneity. Meta-regression analyses revealed that a part of the heterogeneity reflected varying case ascertainment and study designs. The estimates of symptomatic secondary infection risk, based on 20 studies identifying febrile acute respiratory illness among household contacts, also showed substantial variability, with point estimates ranging from 4% to 37%. Conclusions: Transmission of the 2009 pandemic virus in households appeared to vary among countries and settings, with differences in estimates of the secondary infection risk also partly due to differences in study designs.</div>
</front>
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Household Transmission of 2009 Pandemic Influenza A(H1N1): A Systematic Review and Meta-analysis

Household Transmission of 2009 Pandemic Influenza A(H1N1): A Systematic Review and Meta-analysis

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri