A[H1N1] flu and refractory hypoxaemia: Is extracorporeal lung support the holy grail?
Identifieur interne : 002652 ( Main/Exploration ); précédent : 002651; suivant : 002653A[H1N1] flu and refractory hypoxaemia: Is extracorporeal lung support the holy grail?
Auteurs : T V Veenith [Royaume-Uni] ; M. Rana [Royaume-Uni] ; A. Ercole [Royaume-Uni] ; K. Gunning [Royaume-Uni] ; R. Mahroof [Royaume-Uni]Source :
- Thorax [ 0040-6376 ] ; 2011-09.
English descriptors
- Teeft :
- Ards, Care unit, Conventional ventilation, Conventional ventilatory support, Convincing evidence, Distress syndrome, Ecls, Ecmo, Extracorporeal, Extracorporeal lung support, Extracorporeal membrane oxygenation, Fio2, Foundation trust, Health technol, Hypoxaemia, Lung compliance, Oxygenation, Plateau pressure, Positive pressure, Refractory, Refractory hypoxaemia, Replacement therapy, Respiratory failure, Routine implementation, Severe adult, Severe hypoxaemic, Tidal volume, Ventilatory, Ventilatory management.
Abstract
There is a call for methodologically robust randomised clinical trials in adult extracorporeal membrane oxygenation for its routine implementation for patients with “failing” conventional ventilation. Adherence to lung protective ventilation strategies, along with fluid balance [if required early renal replacement therapy] and inotropes to support the circulation to minimise ventilator-induced lung injury, may mitigate deterioration requiring extracorporeal lung support. Currently there is no convincing evidence to routinely advocate extracorporeal lung support in failed conventional ventilation, and a prospective trial is needed to define standard best practice and to tailor extracorporeal lung support referral criteria in young patient cohort with severe refractory respiratory failure.
Url:
DOI: 10.1136/thoraxjnl-2011-200092
Affiliations:
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Adherence to lung protective ventilation strategies, along with fluid balance [if required early renal replacement therapy] and inotropes to support the circulation to minimise ventilator-induced lung injury, may mitigate deterioration requiring extracorporeal lung support. Currently there is no convincing evidence to routinely advocate extracorporeal lung support in failed conventional ventilation, and a prospective trial is needed to define standard best practice and to tailor extracorporeal lung support referral criteria in young patient cohort with severe refractory respiratory failure.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Veenith, T V" sort="Veenith, T V" uniqKey="Veenith T" first="T V" last="Veenith">T V Veenith</name></noRegion><name sortKey="Ercole, A" sort="Ercole, A" uniqKey="Ercole A" first="A" last="Ercole">A. Ercole</name><name sortKey="Gunning, K" sort="Gunning, K" uniqKey="Gunning K" first="K" last="Gunning">K. Gunning</name><name sortKey="Gunning, K" sort="Gunning, K" uniqKey="Gunning K" first="K" last="Gunning">K. Gunning</name><name sortKey="Mahroof, R" sort="Mahroof, R" uniqKey="Mahroof R" first="R" last="Mahroof">R. Mahroof</name><name sortKey="Rana, M" sort="Rana, M" uniqKey="Rana M" first="M" last="Rana">M. Rana</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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