PandemieGrippaleV1, Main, Curation, bibRecord, 000376

Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self‐reported severity and duration of illness

Identifieur interne : 000376 ( Main/Curation ); précédent : 000375; suivant : 000377

Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self‐reported severity and duration of illness

Auteurs : Gro Tunheim ; Ida Laake ; Anna Hayman Robertson ; Kristian Waalen ; Olav Hungnes ; Lisbeth M. N Ss ; Rebecca J. Cox ; Siri Mjaaland ; Lill Trogstad

Source :

Influenza and Other Respiratory Viruses [ 1750-2640 ] ; 2019.

RBID : PMC:6379636

Descripteurs français

KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Anticorps antiviraux (sang), Autorapport, Enquêtes et questionnaires, Enregistrements, Femelle, Grippe humaine (immunologie), Grossesse, Humains, Indice de gravité médicale, Jeune adulte, Sous-type H1N1 du virus de la grippe A, Tests d'inhibition de l'hémagglutination, Vaccination (), Vaccins antigrippaux (usage thérapeutique), Études de cohortes.
MESH :
- immunologie : Grippe humaine.
- sang : Anticorps antiviraux.
- usage thérapeutique : Vaccins antigrippaux.
- Adolescent, Adulte, Adulte d'âge moyen, Autorapport, Enquêtes et questionnaires, Enregistrements, Femelle, Grossesse, Humains, Indice de gravité médicale, Jeune adulte, Sous-type H1N1 du virus de la grippe A, Tests d'inhibition de l'hémagglutination, Vaccination, Études de cohortes.

English descriptors

KwdEn :
- Adolescent, Adult, Antibodies, Viral (blood), Cohort Studies, Female, Hemagglutination Inhibition Tests, Humans, Influenza A Virus, H1N1 Subtype, Influenza Vaccines (therapeutic use), Influenza, Human (immunology), Middle Aged, Pregnancy, Registries, Self Report, Severity of Illness Index, Surveys and Questionnaires, Vaccination (statistics & numerical data), Young Adult.
MESH :
- chemical , blood : Antibodies, Viral.
- chemical , therapeutic use : Influenza Vaccines.
- immunology : Influenza, Human.
- statistics & numerical data : Vaccination.
- Adolescent, Adult, Cohort Studies, Female, Hemagglutination Inhibition Tests, Humans, Influenza A Virus, H1N1 Subtype, Middle Aged, Pregnancy, Registries, Self Report, Severity of Illness Index, Surveys and Questionnaires, Young Adult.

Abstract

Background

A population‐based pregnancy cohort was established in Norway to study potential effects of exposure to the 2009 influenza pandemic or pandemic vaccination during pregnancy.

Objectives

We studied maternal A(H1N1)pdm09‐specific hemagglutination inhibition (HI)‐titer levels and waning in women with influenza‐like illness (ILI) in pregnancy compared to vaccinated women. Moreover, we studied the association between HI‐titers and self‐reported severity and duration of ILI.

Methods

HI‐titers against the pandemic virus were measured in maternal blood samples obtained at birth, 3‐9 months after exposure, and linked with information about pregnancy, influenza and vaccination from national registries and a cohort questionnaire.

Results

Among 1821 pregnant women included, 43.7% were unvaccinated and 19.3% of these had ILI. HI‐titers were low (geometric mean titer (GMT) 11.3) in the unvaccinated women with ILI. Higher HI‐titers (GMT 37.8) were measured in the vaccinated women. Estimated HI‐titer waning was similar for vaccinated women and women with ILI. Most ILI episodes were moderate and lasted 3‐5 days. Women with ILI reporting specific influenza symptoms such as fever or cough had higher HI‐titers than women without these symptoms. Women who reported being “very ill” or illness duration of >5 days had higher HI‐titers than women reporting less severe illness or illness of shorter duration, respectively.

Conclusions

Antibody waning was similar in vaccinated women and women with ILI. More severe ILI or longer duration of illness was associated with higher HI‐titers. Most unvaccinated pregnant women with ILI had low HI‐titers, probably due to moderate illness and HI‐titer waning between exposure and sampling.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379636

DOI: 10.1111/irv.12623
PubMed: 30536590
PubMed Central: 6379636

Links toward previous steps (curation, corpus...)

to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000A86
to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :000A86
to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000095
to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000186
to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000186
to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000176
to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :001F06
to stream Ncbi, to step Curation: Pour aller vers cette notice dans l'étape Curation :001F06
to stream Ncbi, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001F06
to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :000375

Links to Exploration step

PMC:6379636

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self‐reported severity and duration of illness</title>
<author><name sortKey="Tunheim, Gro" sort="Tunheim, Gro" uniqKey="Tunheim G" first="Gro" last="Tunheim">Gro Tunheim</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="irv12623-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Laake, Ida" sort="Laake, Ida" uniqKey="Laake I" first="Ida" last="Laake">Ida Laake</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Robertson, Anna Hayman" sort="Robertson, Anna Hayman" uniqKey="Robertson A" first="Anna Hayman" last="Robertson">Anna Hayman Robertson</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Waalen, Kristian" sort="Waalen, Kristian" uniqKey="Waalen K" first="Kristian" last="Waalen">Kristian Waalen</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hungnes, Olav" sort="Hungnes, Olav" uniqKey="Hungnes O" first="Olav" last="Hungnes">Olav Hungnes</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="N Ss, Lisbeth M" sort="N Ss, Lisbeth M" uniqKey="N Ss L" first="Lisbeth M." last="N Ss">Lisbeth M. N Ss</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cox, Rebecca J" sort="Cox, Rebecca J" uniqKey="Cox R" first="Rebecca J." last="Cox">Rebecca J. Cox</name>
<affiliation><nlm:aff id="irv12623-aff-0002"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="irv12623-aff-0003"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="irv12623-aff-0004"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mjaaland, Siri" sort="Mjaaland, Siri" uniqKey="Mjaaland S" first="Siri" last="Mjaaland">Siri Mjaaland</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="irv12623-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Trogstad, Lill" sort="Trogstad, Lill" uniqKey="Trogstad L" first="Lill" last="Trogstad">Lill Trogstad</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">30536590</idno>
<idno type="pmc">6379636</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379636</idno>
<idno type="RBID">PMC:6379636</idno>
<idno type="doi">10.1111/irv.12623</idno>
<date when="2019">2019</date>
<idno type="wicri:Area/Pmc/Corpus">000A86</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000A86</idno>
<idno type="wicri:Area/Pmc/Curation">000A86</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000A86</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000095</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000095</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:30536590</idno>
<idno type="wicri:Area/PubMed/Corpus">000186</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000186</idno>
<idno type="wicri:Area/PubMed/Curation">000186</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000186</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000176</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000176</idno>
<idno type="wicri:Area/Ncbi/Merge">001F06</idno>
<idno type="wicri:Area/Ncbi/Curation">001F06</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001F06</idno>
<idno type="wicri:doubleKey">1750-2640:2019:Tunheim G:antibody:levels:in</idno>
<idno type="wicri:Area/Main/Merge">000375</idno>
<idno type="wicri:Area/Main/Curation">000376</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self‐reported severity and duration of illness</title>
<author><name sortKey="Tunheim, Gro" sort="Tunheim, Gro" uniqKey="Tunheim G" first="Gro" last="Tunheim">Gro Tunheim</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="irv12623-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Laake, Ida" sort="Laake, Ida" uniqKey="Laake I" first="Ida" last="Laake">Ida Laake</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Robertson, Anna Hayman" sort="Robertson, Anna Hayman" uniqKey="Robertson A" first="Anna Hayman" last="Robertson">Anna Hayman Robertson</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Waalen, Kristian" sort="Waalen, Kristian" uniqKey="Waalen K" first="Kristian" last="Waalen">Kristian Waalen</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hungnes, Olav" sort="Hungnes, Olav" uniqKey="Hungnes O" first="Olav" last="Hungnes">Olav Hungnes</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="N Ss, Lisbeth M" sort="N Ss, Lisbeth M" uniqKey="N Ss L" first="Lisbeth M." last="N Ss">Lisbeth M. N Ss</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Cox, Rebecca J" sort="Cox, Rebecca J" uniqKey="Cox R" first="Rebecca J." last="Cox">Rebecca J. Cox</name>
<affiliation><nlm:aff id="irv12623-aff-0002"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="irv12623-aff-0003"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="irv12623-aff-0004"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mjaaland, Siri" sort="Mjaaland, Siri" uniqKey="Mjaaland S" first="Siri" last="Mjaaland">Siri Mjaaland</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="irv12623-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Trogstad, Lill" sort="Trogstad, Lill" uniqKey="Trogstad L" first="Lill" last="Trogstad">Lill Trogstad</name>
<affiliation><nlm:aff id="irv12623-aff-0001"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Influenza and Other Respiratory Viruses</title>
<idno type="ISSN">1750-2640</idno>
<idno type="eISSN">1750-2659</idno>
<imprint><date when="2019">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Antibodies, Viral (blood)</term>
<term>Cohort Studies</term>
<term>Female</term>
<term>Hemagglutination Inhibition Tests</term>
<term>Humans</term>
<term>Influenza A Virus, H1N1 Subtype</term>
<term>Influenza Vaccines (therapeutic use)</term>
<term>Influenza, Human (immunology)</term>
<term>Middle Aged</term>
<term>Pregnancy</term>
<term>Registries</term>
<term>Self Report</term>
<term>Severity of Illness Index</term>
<term>Surveys and Questionnaires</term>
<term>Vaccination (statistics & numerical data)</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Anticorps antiviraux (sang)</term>
<term>Autorapport</term>
<term>Enquêtes et questionnaires</term>
<term>Enregistrements</term>
<term>Femelle</term>
<term>Grippe humaine (immunologie)</term>
<term>Grossesse</term>
<term>Humains</term>
<term>Indice de gravité médicale</term>
<term>Jeune adulte</term>
<term>Sous-type H1N1 du virus de la grippe A</term>
<term>Tests d'inhibition de l'hémagglutination</term>
<term>Vaccination ()</term>
<term>Vaccins antigrippaux (usage thérapeutique)</term>
<term>Études de cohortes</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Influenza Vaccines</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antiviraux</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Vaccination</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Vaccins antigrippaux</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Cohort Studies</term>
<term>Female</term>
<term>Hemagglutination Inhibition Tests</term>
<term>Humans</term>
<term>Influenza A Virus, H1N1 Subtype</term>
<term>Middle Aged</term>
<term>Pregnancy</term>
<term>Registries</term>
<term>Self Report</term>
<term>Severity of Illness Index</term>
<term>Surveys and Questionnaires</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Autorapport</term>
<term>Enquêtes et questionnaires</term>
<term>Enregistrements</term>
<term>Femelle</term>
<term>Grossesse</term>
<term>Humains</term>
<term>Indice de gravité médicale</term>
<term>Jeune adulte</term>
<term>Sous-type H1N1 du virus de la grippe A</term>
<term>Tests d'inhibition de l'hémagglutination</term>
<term>Vaccination</term>
<term>Études de cohortes</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="irv12623-sec-0001"><title>Background</title>
<p>A population‐based pregnancy cohort was established in Norway to study potential effects of exposure to the 2009 influenza pandemic or pandemic vaccination during pregnancy.</p>
</sec>
<sec id="irv12623-sec-0002"><title>Objectives</title>
<p>We studied maternal A(H1N1)pdm09‐specific hemagglutination inhibition (<styled-content style="fixed-case">HI</styled-content>
)‐titer levels and waning in women with influenza‐like illness (<styled-content style="fixed-case">ILI</styled-content>
) in pregnancy compared to vaccinated women. Moreover, we studied the association between <styled-content style="fixed-case">HI</styled-content>
‐titers and self‐reported severity and duration of <styled-content style="fixed-case">ILI</styled-content>
.</p>
</sec>
<sec id="irv12623-sec-0003"><title>Methods</title>
<p><styled-content style="fixed-case">HI</styled-content>
‐titers against the pandemic virus were measured in maternal blood samples obtained at birth, 3‐9 months after exposure, and linked with information about pregnancy, influenza and vaccination from national registries and a cohort questionnaire.</p>
</sec>
<sec id="irv12623-sec-0004"><title>Results</title>
<p>Among 1821 pregnant women included, 43.7% were unvaccinated and 19.3% of these had <styled-content style="fixed-case">ILI</styled-content>
. <styled-content style="fixed-case">HI</styled-content>
‐titers were low (geometric mean titer (<styled-content style="fixed-case">GMT</styled-content>
) 11.3) in the unvaccinated women with <styled-content style="fixed-case">ILI</styled-content>
. Higher <styled-content style="fixed-case">HI</styled-content>
‐titers (<styled-content style="fixed-case">GMT</styled-content>
 37.8) were measured in the vaccinated women. Estimated <styled-content style="fixed-case">HI</styled-content>
‐titer waning was similar for vaccinated women and women with <styled-content style="fixed-case">ILI</styled-content>
. Most <styled-content style="fixed-case">ILI</styled-content>
 episodes were moderate and lasted 3‐5 days. Women with <styled-content style="fixed-case">ILI</styled-content>
 reporting specific influenza symptoms such as fever or cough had higher <styled-content style="fixed-case">HI</styled-content>
‐titers than women without these symptoms. Women who reported being “very ill” or illness duration of >5 days had higher <styled-content style="fixed-case">HI</styled-content>
‐titers than women reporting less severe illness or illness of shorter duration, respectively.</p>
</sec>
<sec id="irv12623-sec-0005"><title>Conclusions</title>
<p>Antibody waning was similar in vaccinated women and women with <styled-content style="fixed-case">ILI</styled-content>
. More severe <styled-content style="fixed-case">ILI</styled-content>
 or longer duration of illness was associated with higher <styled-content style="fixed-case">HI</styled-content>
‐titers. Most unvaccinated pregnant women with <styled-content style="fixed-case">ILI</styled-content>
 had low <styled-content style="fixed-case">HI</styled-content>
‐titers, probably due to moderate illness and <styled-content style="fixed-case">HI</styled-content>
‐titer waning between exposure and sampling.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/PandemieGrippaleV1/Data/Main/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000376 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 000376 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    PandemieGrippaleV1
   |flux=    Main
   |étape=   Curation
   |type=    RBID
   |clé=     PMC:6379636
   |texte=   Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self‐reported severity and duration of illness
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Curation/RBID.i   -Sk "pubmed:30536590" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a PandemieGrippaleV1

This area was generated with Dilib version V0.6.34.
Data generation: Wed Jun 10 11:04:28 2020. Site generation: Sun Mar 28 09:10:28 2021

	Serveur d'exploration sur les pandémies grippales
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur les pandémies grippales

Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self‐reported severity and duration of illness

Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self‐reported severity and duration of illness

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki