Drivers of Rift Valley fever epidemics in Madagascar.
Identifieur interne : 000170 ( Hal/Corpus ); précédent : 000169; suivant : 000171Drivers of Rift Valley fever epidemics in Madagascar.
Auteurs : Renaud Lancelot ; Marina Béral ; Vincent Michel Rakotoharinome ; Soa-Fy Andriamandimby ; Jean-Michel Heraud ; Caroline Coste ; Andrea Apolloni ; Cécile Squarzoni-Diaw ; Stéphane De La Rocque ; Pierre B H. Formenty ; Jérémy Bouyer ; G R William Wint ; Eric CardinaleSource :
- Proceedings of the National Academy of Sciences of the United States of America [ 0027-8424 ] ; 2017-01-31.
English descriptors
Abstract
Rift Valley fever (RVF) is a vector-borne viral disease widespread in Africa. The primary cycle involves mosquitoes and wild and domestic ruminant hosts. Humans are usually contaminated after contact with infected ruminants. As many environmental, agricultural, epidemiological, and anthropogenic factors are implicated in RVF spread, the multidisciplinary One Health approach was needed to identify the drivers of RVF epidemics in Madagascar. We examined the environmental patterns associated with these epidemics, comparing human and ruminant serological data with environmental and cattle-trade data. In contrast to East Africa, environmental drivers did not trigger the epidemics: They only modulated local Rift Valley fever virus (RVFV) transmission in ruminants. Instead, RVFV was introduced through ruminant trade and subsequent movement of cattle between trade hubs caused its long-distance spread within the country. Contact with cattle brought in from infected districts was associated with higher infection risk in slaughterhouse workers. The finding that anthropogenic rather than environmental factors are the main drivers of RVF infection in humans can be used to design better prevention and early detection in the case of RVF resurgence in the region.
Url:
DOI: 10.1073/pnas.1607948114
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Hal:pasteur-01498224Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Drivers of Rift Valley fever epidemics in Madagascar.</title>
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<author><name sortKey="Heraud, Jean Michel" sort="Heraud, Jean Michel" uniqKey="Heraud J" first="Jean-Michel" last="Heraud">Jean-Michel Heraud</name>
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<idno type="DOI">10.1073/pnas.1607948114</idno>
<series><title level="j">Proceedings of the National Academy of Sciences of the United States of America </title>
<idno type="ISSN">0027-8424</idno>
<imprint><date type="datePub">2017-01-31</date>
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<profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>El Niño</term>
<term>One Health</term>
<term>cattle trade</term>
<term>vector-borne infection</term>
<term>zoonosis</term>
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<front><div type="abstract" xml:lang="en"> <p>Rift Valley fever (RVF) is a vector-borne viral disease widespread in Africa. The primary cycle involves mosquitoes and wild and domestic ruminant hosts. Humans are usually contaminated after contact with infected ruminants. As many environmental, agricultural, epidemiological, and anthropogenic factors are implicated in RVF spread, the multidisciplinary One Health approach was needed to identify the drivers of RVF epidemics in Madagascar. We examined the environmental patterns associated with these epidemics, comparing human and ruminant serological data with environmental and cattle-trade data. In contrast to East Africa, environmental drivers did not trigger the epidemics: They only modulated local Rift Valley fever virus (RVFV) transmission in ruminants. Instead, RVFV was introduced through ruminant trade and subsequent movement of cattle between trade hubs caused its long-distance spread within the country. Contact with cattle brought in from infected districts was associated with higher infection risk in slaughterhouse workers. The finding that anthropogenic rather than environmental factors are the main drivers of RVF infection in humans can be used to design better prevention and early detection in the case of RVF resurgence in the region.</p>
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<hal api="V3"> <titleStmt> <title xml:lang="en">Drivers of Rift Valley fever epidemics in Madagascar.</title>
<author role="aut"> <persName> <forename type="first">Renaud</forename>
<surname>Lancelot</surname>
</persName>
<idno type="halauthorid">369191</idno>
<affiliation ref="#struct-498087"></affiliation>
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<author role="aut"> <persName> <forename type="first">Marina</forename>
<surname>Béral</surname>
</persName>
<idno type="halauthorid">1519553</idno>
<affiliation ref="#struct-498087"></affiliation>
<affiliation ref="#struct-174264"></affiliation>
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<author role="aut"> <persName> <forename type="first">Vincent Michel</forename>
<surname>Rakotoharinome</surname>
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<idno type="halauthorid">1323101</idno>
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<idno type="halRefHtml">Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2017, 114 (5), pp.938-943. ⟨10.1073/pnas.1607948114⟩</idno>
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<idno type="stamp" n="OPENAIRE">OpenAIRE</idno>
<idno type="stamp" n="INRA">INRA - Institut national de la recherche agronomique</idno>
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<idno type="stamp" n="RIIP">Institut Pasteur RIIP (Réseau International)</idno>
<idno type="stamp" n="UNIV-REUNION">Université de la Réunion</idno>
<idno type="stamp" n="AGREENIUM">Archive ouverte en agrobiosciences</idno>
<idno type="stamp" n="RIIP_MADAGASCAR" corresp="RIIP">Institut Pasteur de Madagascar</idno>
<idno type="stamp" n="PAPANGUE">Papangue</idno>
<idno type="stamp" n="INRAE">Institut National de Recherche en Agriculture, Alimentation et Environnement</idno>
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<sourceDesc> <biblStruct> <analytic> <title xml:lang="en">Drivers of Rift Valley fever epidemics in Madagascar.</title>
<author role="aut"> <persName> <forename type="first">Renaud</forename>
<surname>Lancelot</surname>
</persName>
<idno type="halauthorid">369191</idno>
<affiliation ref="#struct-498087"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Marina</forename>
<surname>Béral</surname>
</persName>
<idno type="halauthorid">1519553</idno>
<affiliation ref="#struct-498087"></affiliation>
<affiliation ref="#struct-174264"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Vincent Michel</forename>
<surname>Rakotoharinome</surname>
</persName>
<idno type="halauthorid">1323101</idno>
<affiliation ref="#struct-510330"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Soa-Fy</forename>
<surname>Andriamandimby</surname>
</persName>
<idno type="halauthorid">1519554</idno>
<affiliation ref="#struct-164772"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Jean-Michel</forename>
<surname>Heraud</surname>
</persName>
<email type="md5">1849a0600a4a62c48f329d055ab8ca5b</email>
<email type="domain">pasteur.mg</email>
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<idno type="ResearcherId">http://www.researcherid.com/rid/O-1464-2013</idno>
<affiliation ref="#struct-164772"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Caroline</forename>
<surname>Coste</surname>
</persName>
<idno type="halauthorid">1519555</idno>
<affiliation ref="#struct-498087"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Andrea</forename>
<surname>Apolloni</surname>
</persName>
<email type="md5">d72a8786b9f5736b9f538e3198fa7f73</email>
<email type="domain">cirad.fr</email>
<idno type="halauthorid">1519556</idno>
<affiliation ref="#struct-498087"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Cécile</forename>
<surname>Squarzoni-Diaw</surname>
</persName>
<idno type="halauthorid">1519557</idno>
<affiliation ref="#struct-510331"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Stéphane</forename>
<surname>De La Rocque</surname>
</persName>
<idno type="halauthorid">464404</idno>
<affiliation ref="#struct-498087"></affiliation>
<affiliation ref="#struct-510332"></affiliation>
<affiliation ref="#struct-510334"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Pierre B H</forename>
<surname>Formenty</surname>
</persName>
<idno type="halauthorid">1519558</idno>
<affiliation ref="#struct-510336"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Jérémy</forename>
<surname>Bouyer</surname>
</persName>
<idno type="halauthorid">663810</idno>
<affiliation ref="#struct-498087"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">G R William</forename>
<surname>Wint</surname>
</persName>
<idno type="halauthorid">1519559</idno>
<affiliation ref="#struct-510337"></affiliation>
</author>
<author role="aut"> <persName> <forename type="first">Eric</forename>
<surname>Cardinale</surname>
</persName>
<idno type="halauthorid">643183</idno>
<affiliation ref="#struct-234808"></affiliation>
<affiliation ref="#struct-498087"></affiliation>
</author>
</analytic>
<monogr> <idno type="halJournalId" status="VALID">7969</idno>
<idno type="issn">0027-8424</idno>
<idno type="eissn">1091-6490</idno>
<title level="j">Proceedings of the National Academy of Sciences of the United States of America </title>
<imprint> <publisher>National Academy of Sciences</publisher>
<biblScope unit="volume">114</biblScope>
<biblScope unit="issue">5</biblScope>
<biblScope unit="pp">938-943</biblScope>
<date type="datePub">2017-01-31</date>
</imprint>
</monogr>
<idno type="doi">10.1073/pnas.1607948114</idno>
<idno type="prodinra">390438</idno>
<idno type="pubmed">28096420</idno>
<idno type="pubmedcentral">PMC5293023</idno>
<idno type="wos">000393196300059</idno>
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</sourceDesc>
<profileDesc> <langUsage> <language ident="en">English</language>
</langUsage>
<textClass> <keywords scheme="author"> <term xml:lang="en">vector-borne infection</term>
<term xml:lang="en">cattle trade</term>
<term xml:lang="en">zoonosis</term>
<term xml:lang="en">El Niño</term>
<term xml:lang="en">One Health</term>
</keywords>
<classCode scheme="halDomain" n="sdv.mp.vir">Life Sciences [q-bio]/Microbiology and Parasitology/Virology</classCode>
<classCode scheme="halTypology" n="ART">Journal articles</classCode>
</textClass>
<abstract xml:lang="en"> <p>Rift Valley fever (RVF) is a vector-borne viral disease widespread in Africa. The primary cycle involves mosquitoes and wild and domestic ruminant hosts. Humans are usually contaminated after contact with infected ruminants. As many environmental, agricultural, epidemiological, and anthropogenic factors are implicated in RVF spread, the multidisciplinary One Health approach was needed to identify the drivers of RVF epidemics in Madagascar. We examined the environmental patterns associated with these epidemics, comparing human and ruminant serological data with environmental and cattle-trade data. In contrast to East Africa, environmental drivers did not trigger the epidemics: They only modulated local Rift Valley fever virus (RVFV) transmission in ruminants. Instead, RVFV was introduced through ruminant trade and subsequent movement of cattle between trade hubs caused its long-distance spread within the country. Contact with cattle brought in from infected districts was associated with higher infection risk in slaughterhouse workers. The finding that anthropogenic rather than environmental factors are the main drivers of RVF infection in humans can be used to design better prevention and early detection in the case of RVF resurgence in the region.</p>
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