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Do leprosy and tuberculosis generate a systemic inflammatory shift? Setting the ground for a new dialogue between experimental immunology and bioarchaeology.

Identifieur interne : 000005 ( Main/Merge ); précédent : 000004; suivant : 000006

Do leprosy and tuberculosis generate a systemic inflammatory shift? Setting the ground for a new dialogue between experimental immunology and bioarchaeology.

Auteurs : Fabian A. Crespo [États-Unis] ; Christopher K. Klaes [États-Unis] ; Andrew E. Switala [États-Unis] ; Sharon N. Dewitte [États-Unis]

Source :

RBID : pubmed:27704524

Abstract

It is possible that during long lasting chronic infections such as tuberculosis (TB) and leprosy individuals who generate a stronger immune response will produce a chronic shift in the systemic levels of inflammatory proteins. Consequently, the systemic immunological shift could affect inflammatory responses against other persistent pathogens such as Porphyromonas gingivalis associated with periodontal disease (PD).

DOI: 10.1002/ajpa.23104
PubMed: 27704524

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pubmed:27704524

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