Proton magnetic resonance spectroscopy in Steele-Richardson-Olszewski syndrome.
Identifieur interne : 004592 ( PubMed/Corpus ); précédent : 004591; suivant : 004593Proton magnetic resonance spectroscopy in Steele-Richardson-Olszewski syndrome.
Auteurs : C A Davie ; G J Barker ; C. Machado ; D H Miller ; A J LeesSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1997.
English descriptors
- KwdEn :
- Adult, Aged, Aspartic Acid (analogs & derivatives), Aspartic Acid (analysis), Basal Ganglia (chemistry), Basal Ganglia (pathology), Case-Control Studies, Choline (analysis), Creatine (analysis), Diagnosis, Differential, Globus Pallidus (pathology), Humans, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Middle Aged, Supranuclear Palsy, Progressive (diagnosis).
- MESH :
- chemical , analogs & derivatives : Aspartic Acid.
- chemical , analysis : Aspartic Acid, Choline, Creatine.
- chemistry : Basal Ganglia.
- diagnosis : Supranuclear Palsy, Progressive.
- pathology : Basal Ganglia, Globus Pallidus.
- Adult, Aged, Case-Control Studies, Diagnosis, Differential, Humans, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Middle Aged.
Abstract
Proton magnetic resonance spectroscopy, localized to the lentiform nucleus, was carried out in nine patients with a clinical diagnosis of Steele-Richardson-Olszewski syndrome (SRO) and in eight healthy age-matched controls. Three of the nine SRO patients had a so-called "eye of the tiger sign" with high signal in the globus pallidus surrounded by a ring of low signal on T2 weighted magnetic resonance imaging previously only reported in Hallervorden-Spatz disease. One of these patients had pathologically proven SRO at postmortem. The SRO group showed a significant reduction in the median concentration from N-acetyl groups (median, 6.87 mM; range, 4.92-10.59 mM; p < 0.015) compared with the control group (median, 9.85 mM; range, 9.26-11.0 mM). The N-acetylaspartate concentration was significantly reduced in seven of the nine patients studied. The reduction of the N-acetylaspartate-creatine ratio from the lentiform nucleus in the SRO group may reflect neuronal loss, occurring predominantly in the globus pallidus. Proton magnetic resonance spectroscopy may be a useful, noninvasive technique to help differentiate the various parkinsonian syndromes.
DOI: 10.1002/mds.870120525
PubMed: 9380064
Links to Exploration step
pubmed:9380064Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Proton magnetic resonance spectroscopy in Steele-Richardson-Olszewski syndrome.</title>
<author><name sortKey="Davie, C A" sort="Davie, C A" uniqKey="Davie C" first="C A" last="Davie">C A Davie</name>
<affiliation><nlm:affiliation>National Hospital for Neurology and Neurosurgery, London, U.K.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Barker, G J" sort="Barker, G J" uniqKey="Barker G" first="G J" last="Barker">G J Barker</name>
</author>
<author><name sortKey="Machado, C" sort="Machado, C" uniqKey="Machado C" first="C" last="Machado">C. Machado</name>
</author>
<author><name sortKey="Miller, D H" sort="Miller, D H" uniqKey="Miller D" first="D H" last="Miller">D H Miller</name>
</author>
<author><name sortKey="Lees, A J" sort="Lees, A J" uniqKey="Lees A" first="A J" last="Lees">A J Lees</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1997">1997</date>
<idno type="RBID">pubmed:9380064</idno>
<idno type="pmid">9380064</idno>
<idno type="doi">10.1002/mds.870120525</idno>
<idno type="wicri:Area/PubMed/Corpus">004592</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Proton magnetic resonance spectroscopy in Steele-Richardson-Olszewski syndrome.</title>
<author><name sortKey="Davie, C A" sort="Davie, C A" uniqKey="Davie C" first="C A" last="Davie">C A Davie</name>
<affiliation><nlm:affiliation>National Hospital for Neurology and Neurosurgery, London, U.K.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Barker, G J" sort="Barker, G J" uniqKey="Barker G" first="G J" last="Barker">G J Barker</name>
</author>
<author><name sortKey="Machado, C" sort="Machado, C" uniqKey="Machado C" first="C" last="Machado">C. Machado</name>
</author>
<author><name sortKey="Miller, D H" sort="Miller, D H" uniqKey="Miller D" first="D H" last="Miller">D H Miller</name>
</author>
<author><name sortKey="Lees, A J" sort="Lees, A J" uniqKey="Lees A" first="A J" last="Lees">A J Lees</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="1997" type="published">1997</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aspartic Acid (analogs & derivatives)</term>
<term>Aspartic Acid (analysis)</term>
<term>Basal Ganglia (chemistry)</term>
<term>Basal Ganglia (pathology)</term>
<term>Case-Control Studies</term>
<term>Choline (analysis)</term>
<term>Creatine (analysis)</term>
<term>Diagnosis, Differential</term>
<term>Globus Pallidus (pathology)</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Magnetic Resonance Spectroscopy</term>
<term>Middle Aged</term>
<term>Supranuclear Palsy, Progressive (diagnosis)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Aspartic Acid</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Aspartic Acid</term>
<term>Choline</term>
<term>Creatine</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Basal Ganglia</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Supranuclear Palsy, Progressive</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Basal Ganglia</term>
<term>Globus Pallidus</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Case-Control Studies</term>
<term>Diagnosis, Differential</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Magnetic Resonance Spectroscopy</term>
<term>Middle Aged</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Proton magnetic resonance spectroscopy, localized to the lentiform nucleus, was carried out in nine patients with a clinical diagnosis of Steele-Richardson-Olszewski syndrome (SRO) and in eight healthy age-matched controls. Three of the nine SRO patients had a so-called "eye of the tiger sign" with high signal in the globus pallidus surrounded by a ring of low signal on T2 weighted magnetic resonance imaging previously only reported in Hallervorden-Spatz disease. One of these patients had pathologically proven SRO at postmortem. The SRO group showed a significant reduction in the median concentration from N-acetyl groups (median, 6.87 mM; range, 4.92-10.59 mM; p < 0.015) compared with the control group (median, 9.85 mM; range, 9.26-11.0 mM). The N-acetylaspartate concentration was significantly reduced in seven of the nine patients studied. The reduction of the N-acetylaspartate-creatine ratio from the lentiform nucleus in the SRO group may reflect neuronal loss, occurring predominantly in the globus pallidus. Proton magnetic resonance spectroscopy may be a useful, noninvasive technique to help differentiate the various parkinsonian syndromes.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">9380064</PMID>
<DateCreated><Year>1997</Year>
<Month>11</Month>
<Day>07</Day>
</DateCreated>
<DateCompleted><Year>1997</Year>
<Month>11</Month>
<Day>07</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN>
<JournalIssue CitedMedium="Print"><Volume>12</Volume>
<Issue>5</Issue>
<PubDate><Year>1997</Year>
<Month>Sep</Month>
</PubDate>
</JournalIssue>
<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
</Journal>
<ArticleTitle>Proton magnetic resonance spectroscopy in Steele-Richardson-Olszewski syndrome.</ArticleTitle>
<Pagination><MedlinePgn>767-71</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Proton magnetic resonance spectroscopy, localized to the lentiform nucleus, was carried out in nine patients with a clinical diagnosis of Steele-Richardson-Olszewski syndrome (SRO) and in eight healthy age-matched controls. Three of the nine SRO patients had a so-called "eye of the tiger sign" with high signal in the globus pallidus surrounded by a ring of low signal on T2 weighted magnetic resonance imaging previously only reported in Hallervorden-Spatz disease. One of these patients had pathologically proven SRO at postmortem. The SRO group showed a significant reduction in the median concentration from N-acetyl groups (median, 6.87 mM; range, 4.92-10.59 mM; p < 0.015) compared with the control group (median, 9.85 mM; range, 9.26-11.0 mM). The N-acetylaspartate concentration was significantly reduced in seven of the nine patients studied. The reduction of the N-acetylaspartate-creatine ratio from the lentiform nucleus in the SRO group may reflect neuronal loss, occurring predominantly in the globus pallidus. Proton magnetic resonance spectroscopy may be a useful, noninvasive technique to help differentiate the various parkinsonian syndromes.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Davie</LastName>
<ForeName>C A</ForeName>
<Initials>CA</Initials>
<AffiliationInfo><Affiliation>National Hospital for Neurology and Neurosurgery, London, U.K.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Barker</LastName>
<ForeName>G J</ForeName>
<Initials>GJ</Initials>
</Author>
<Author ValidYN="Y"><LastName>Machado</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Miller</LastName>
<ForeName>D H</ForeName>
<Initials>DH</Initials>
</Author>
<Author ValidYN="Y"><LastName>Lees</LastName>
<ForeName>A J</ForeName>
<Initials>AJ</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>UNITED STATES</Country>
<MedlineTA>Mov Disord</MedlineTA>
<NlmUniqueID>8610688</NlmUniqueID>
<ISSNLinking>0885-3185</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>30KYC7MIAI</RegistryNumber>
<NameOfSubstance UI="D001224">Aspartic Acid</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>997-55-7</RegistryNumber>
<NameOfSubstance UI="C000179">N-acetylaspartate</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>MU72812GK0</RegistryNumber>
<NameOfSubstance UI="D003401">Creatine</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>N91BDP6H0X</RegistryNumber>
<NameOfSubstance UI="D002794">Choline</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001224">Aspartic Acid</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000031">analogs & derivatives</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000032">analysis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001479">Basal Ganglia</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000737">chemistry</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D016022">Case-Control Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002794">Choline</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000032">analysis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003401">Creatine</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000032">analysis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003937">Diagnosis, Differential</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005917">Globus Pallidus</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008279">Magnetic Resonance Imaging</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D009682">Magnetic Resonance Spectroscopy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D013494">Supranuclear Palsy, Progressive</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000175">diagnosis</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1997</Year>
<Month>9</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>1997</Year>
<Month>9</Month>
<Day>26</Day>
<Hour>0</Hour>
<Minute>1</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>1997</Year>
<Month>9</Month>
<Day>26</Day>
<Hour>0</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">9380064</ArticleId>
<ArticleId IdType="doi">10.1002/mds.870120525</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004592 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 004592 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= PubMed |étape= Corpus |type= RBID |clé= pubmed:9380064 |texte= Proton magnetic resonance spectroscopy in Steele-Richardson-Olszewski syndrome. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:9380064" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a MovDisordV3
![]() | This area was generated with Dilib version V0.6.23. | ![]() |