MovDisordV3, PubMed, Corpus, bibRecord, 002069

The prodromal phase of sporadic Parkinson's disease: does it exist and if so how long is it?

Identifieur interne : 002069 ( PubMed/Corpus ); précédent : 002068; suivant : 002070

The prodromal phase of sporadic Parkinson's disease: does it exist and if so how long is it?

Auteurs : Christopher H. Hawkes

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2008.

RBID : pubmed:18759359

English descriptors

KwdEn :
- Humans, Olfaction Disorders (complications), Olfaction Disorders (pathology), Parkinson Disease (complications), Parkinson Disease (diagnosis), Primary Dysautonomias (complications), Primary Dysautonomias (pathology), Risk Factors, Severity of Illness Index, Sleep Disorders (complications), Sleep Disorders (pathology).
MESH :
- complications : Olfaction Disorders, Parkinson Disease, Primary Dysautonomias, Sleep Disorders.
- diagnosis : Parkinson Disease.
- pathology : Olfaction Disorders, Primary Dysautonomias, Sleep Disorders.
- Humans, Risk Factors, Severity of Illness Index.

Abstract

It is frequently assumed that idiopathic Parkinson's disease starts with several nonmotor symptoms and signs, but the evidence for this stage in the disease process is of variable quality. This review evaluates the more robust prospective or pathologically confirmed publications to establish whether there is a premotor period and if so what is its duration. The most informative studies are considered to be those concerned with olfaction, dysautonomia, and sleep disorder. Estimates for the duration of the prodromal phase vary from months to decades. It is concluded that there probably is an early phase in the disease where a variety of nonmotor features develop, but the sequence and time of onset of such features is not well established.

DOI: 10.1002/mds.22242
PubMed: 18759359

Links to Exploration step

pubmed:18759359

Le document en format XML

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<term>Severity of Illness Index</term>
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<term>Sleep Disorders (pathology)</term>
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<front><div type="abstract" xml:lang="en">It is frequently assumed that idiopathic Parkinson's disease starts with several nonmotor symptoms and signs, but the evidence for this stage in the disease process is of variable quality. This review evaluates the more robust prospective or pathologically confirmed publications to establish whether there is a premotor period and if so what is its duration. The most informative studies are considered to be those concerned with olfaction, dysautonomia, and sleep disorder. Estimates for the duration of the prodromal phase vary from months to decades. It is concluded that there probably is an early phase in the disease where a variety of nonmotor features develop, but the sequence and time of onset of such features is not well established.</div>
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Movement Disorders (revue)

The prodromal phase of sporadic Parkinson's disease: does it exist and if so how long is it?

The prodromal phase of sporadic Parkinson's disease: does it exist and if so how long is it?

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki