Self-management rehabilitation and health-related quality of life in Parkinson's disease: a randomized controlled trial.
Identifieur interne : 001A20 ( PubMed/Corpus ); précédent : 001A19; suivant : 001A21Self-management rehabilitation and health-related quality of life in Parkinson's disease: a randomized controlled trial.
Auteurs : Linda Tickle-Degnen ; Terry Ellis ; Marie H. Saint-Hilaire ; Cathi A. Thomas ; Robert C. WagenaarSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2010.
English descriptors
- KwdEn :
- Aged, Combined Modality Therapy (methods), Disability Evaluation, Exercise Therapy (methods), Female, Follow-Up Studies, Health Status, Humans, Male, Middle Aged, Parkinson Disease (psychology), Parkinson Disease (rehabilitation), Parkinson Disease (therapy), Psychiatric Status Rating Scales, Quality of Life (psychology), Questionnaires, Self Care (methods), Severity of Illness Index, Social Support, Time Factors, Treatment Outcome.
- MESH :
- methods : Combined Modality Therapy, Exercise Therapy, Self Care.
- psychology : Parkinson Disease, Quality of Life.
- rehabilitation : Parkinson Disease.
- therapy : Parkinson Disease.
- Aged, Disability Evaluation, Female, Follow-Up Studies, Health Status, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Questionnaires, Severity of Illness Index, Social Support, Time Factors, Treatment Outcome.
Abstract
The purpose of this randomized controlled trial was to determine whether increasing hours of self-management rehabilitation had increasing benefits for health-related quality of life (HRQOL) in Parkinson's disease beyond best medical treatment, whether effects persisted at 2 and 6 months of follow-up, and whether targeted compared with nontargeted HRQOL domains responded more to rehabilitation. Participants on best medication therapy were randomly assigned to one of three conditions for 6 weeks intervention: 0 hours of rehabilitation; 18 hours of clinic group rehabilitation plus 9 hours of attention control social sessions; and 27 hours of rehabilitation, with 18 in clinic group rehabilitation and 9 hours of rehabilitation designed to transfer clinic training into home and community routines. Results (N = 116) showed that at 6 weeks, there was a beneficial effect of increased rehabilitation hours on HRQOL measured with the Parkinson's Disease Questionnaire-39 summary index (F(1,112) = 6.48, eta = 0.23, CI = 0.05-0.40, P = 0.01). Benefits persisted at follow-up. The difference between 18 and 27 hours was not significant. Clinically relevant improvement occurred at a greater rate for 18 and 27 hours (54% improved) than for 0 hours (18% improved), a significant 36% difference in rates (95% CI = 20-52% difference). Effects were largest in two targeted domains: communication and mobility. More concerns with mobility and activities of daily living at baseline predicted more benefit from rehabilitation.
DOI: 10.1002/mds.22940
PubMed: 20077478
Links to Exploration step
pubmed:20077478Le document en format XML
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Thomas</name></author><author><name sortKey="Wagenaar, Robert C" sort="Wagenaar, Robert C" uniqKey="Wagenaar R" first="Robert C" last="Wagenaar">Robert C. Wagenaar</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="doi">10.1002/mds.22940</idno><idno type="RBID">pubmed:20077478</idno><idno type="pmid">20077478</idno><idno type="wicri:Area/PubMed/Corpus">001A20</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Self-management rehabilitation and health-related quality of life in Parkinson's disease: a randomized controlled trial.</title><author><name sortKey="Tickle Degnen, Linda" sort="Tickle Degnen, Linda" uniqKey="Tickle Degnen L" first="Linda" last="Tickle-Degnen">Linda Tickle-Degnen</name><affiliation><nlm:affiliation>Department of Occupational Therapy, Tufts University, Medford, Massachusetts 02155, USA. Linda.Tickle_Degnen@tufts.edu</nlm:affiliation></affiliation></author><author><name sortKey="Ellis, Terry" sort="Ellis, Terry" uniqKey="Ellis T" first="Terry" last="Ellis">Terry Ellis</name></author><author><name sortKey="Saint Hilaire, Marie H" sort="Saint Hilaire, Marie H" uniqKey="Saint Hilaire M" first="Marie H" last="Saint-Hilaire">Marie H. Saint-Hilaire</name></author><author><name sortKey="Thomas, Cathi A" sort="Thomas, Cathi A" uniqKey="Thomas C" first="Cathi A" last="Thomas">Cathi A. Thomas</name></author><author><name sortKey="Wagenaar, Robert C" sort="Wagenaar, Robert C" uniqKey="Wagenaar R" first="Robert C" last="Wagenaar">Robert C. Wagenaar</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Combined Modality Therapy (methods)</term><term>Disability Evaluation</term><term>Exercise Therapy (methods)</term><term>Female</term><term>Follow-Up Studies</term><term>Health Status</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (psychology)</term><term>Parkinson Disease (rehabilitation)</term><term>Parkinson Disease (therapy)</term><term>Psychiatric Status Rating Scales</term><term>Quality of Life (psychology)</term><term>Questionnaires</term><term>Self Care (methods)</term><term>Severity of Illness Index</term><term>Social Support</term><term>Time Factors</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Combined Modality Therapy</term><term>Exercise Therapy</term><term>Self Care</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Parkinson Disease</term><term>Quality of Life</term></keywords><keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Disability Evaluation</term><term>Female</term><term>Follow-Up Studies</term><term>Health Status</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Psychiatric Status Rating Scales</term><term>Questionnaires</term><term>Severity of Illness Index</term><term>Social Support</term><term>Time Factors</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The purpose of this randomized controlled trial was to determine whether increasing hours of self-management rehabilitation had increasing benefits for health-related quality of life (HRQOL) in Parkinson's disease beyond best medical treatment, whether effects persisted at 2 and 6 months of follow-up, and whether targeted compared with nontargeted HRQOL domains responded more to rehabilitation. Participants on best medication therapy were randomly assigned to one of three conditions for 6 weeks intervention: 0 hours of rehabilitation; 18 hours of clinic group rehabilitation plus 9 hours of attention control social sessions; and 27 hours of rehabilitation, with 18 in clinic group rehabilitation and 9 hours of rehabilitation designed to transfer clinic training into home and community routines. Results (N = 116) showed that at 6 weeks, there was a beneficial effect of increased rehabilitation hours on HRQOL measured with the Parkinson's Disease Questionnaire-39 summary index (F(1,112) = 6.48, eta = 0.23, CI = 0.05-0.40, P = 0.01). Benefits persisted at follow-up. The difference between 18 and 27 hours was not significant. Clinically relevant improvement occurred at a greater rate for 18 and 27 hours (54% improved) than for 0 hours (18% improved), a significant 36% difference in rates (95% CI = 20-52% difference). Effects were largest in two targeted domains: communication and mobility. More concerns with mobility and activities of daily living at baseline predicted more benefit from rehabilitation.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">20077478</PMID><DateCreated><Year>2010</Year><Month>03</Month><Day>02</Day></DateCreated><DateCompleted><Year>2010</Year><Month>06</Month><Day>16</Day></DateCompleted><DateRevised><Year>2014</Year><Month>09</Month><Day>09</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN><JournalIssue CitedMedium="Internet"><Volume>25</Volume><Issue>2</Issue><PubDate><Year>2010</Year><Month>Jan</Month><Day>30</Day></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Self-management rehabilitation and health-related quality of life in Parkinson's disease: a randomized controlled trial.</ArticleTitle><Pagination><MedlinePgn>194-204</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.22940</ELocationID><Abstract><AbstractText>The purpose of this randomized controlled trial was to determine whether increasing hours of self-management rehabilitation had increasing benefits for health-related quality of life (HRQOL) in Parkinson's disease beyond best medical treatment, whether effects persisted at 2 and 6 months of follow-up, and whether targeted compared with nontargeted HRQOL domains responded more to rehabilitation. Participants on best medication therapy were randomly assigned to one of three conditions for 6 weeks intervention: 0 hours of rehabilitation; 18 hours of clinic group rehabilitation plus 9 hours of attention control social sessions; and 27 hours of rehabilitation, with 18 in clinic group rehabilitation and 9 hours of rehabilitation designed to transfer clinic training into home and community routines. Results (N = 116) showed that at 6 weeks, there was a beneficial effect of increased rehabilitation hours on HRQOL measured with the Parkinson's Disease Questionnaire-39 summary index (F(1,112) = 6.48, eta = 0.23, CI = 0.05-0.40, P = 0.01). Benefits persisted at follow-up. The difference between 18 and 27 hours was not significant. Clinically relevant improvement occurred at a greater rate for 18 and 27 hours (54% improved) than for 0 hours (18% improved), a significant 36% difference in rates (95% CI = 20-52% difference). Effects were largest in two targeted domains: communication and mobility. More concerns with mobility and activities of daily living at baseline predicted more benefit from rehabilitation.</AbstractText><CopyrightInformation>(c) 2010 Movement Disorder Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tickle-Degnen</LastName><ForeName>Linda</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Occupational Therapy, Tufts University, Medford, Massachusetts 02155, USA. Linda.Tickle_Degnen@tufts.edu</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ellis</LastName><ForeName>Terry</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Saint-Hilaire</LastName><ForeName>Marie H</ForeName><Initials>MH</Initials></Author><Author ValidYN="Y"><LastName>Thomas</LastName><ForeName>Cathi A</ForeName><Initials>CA</Initials></Author><Author ValidYN="Y"><LastName>Wagenaar</LastName><ForeName>Robert C</ForeName><Initials>RC</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>NAG21152</GrantID><Agency>PHS HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 AG021152</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R01 AG021152-03</GrantID><Acronym>AG</Acronym><Agency>NIA NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016449">Randomized Controlled Trial</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>J Neurol Sci. 2000 Mar 15;174(2):127-36</RefSource><PMID Version="1">10727698</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Phys Med Rehabil. 2009 Jan;90(1):43-50</RefSource><PMID Version="1">19154828</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Phys Med Rehabil. 2001 Apr;82(4):509-15</RefSource><PMID 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Version="1">11273056</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D003131">Combined Modality Therapy</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004185">Disability Evaluation</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D005081">Exercise Therapy</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005500">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D006304">Health Status</DescriptorName></MeshHeading><MeshHeading><DescriptorName 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UI="D011795">Questionnaires</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D012648">Self Care</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012720">Severity of Illness Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012944">Social Support</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D013997">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">NIHMS160445</OtherID><OtherID Source="NLM">PMC2831132</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2010</Year><Month>1</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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