Movement Disorders (revue)

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Mortality in Parkinson's disease: a 38-year follow-up study.

Identifieur interne : 000168 ( PubMed/Checkpoint ); précédent : 000167; suivant : 000169

Mortality in Parkinson's disease: a 38-year follow-up study.

Auteurs : Bernadette Pinter [Autriche] ; Anja Diem-Zangerl ; Gregor Karl Wenning ; Christoph Scherfler ; Willi Oberaigner ; Klaus Seppi ; Werner Poewe [Autriche]

Source :

RBID : pubmed:25447933

English descriptors

Abstract

In this study we report on the outcome including overall and cause-specific mortality of Parkinson's disease (PD) patients subsequent to 38 years of surveillance. This is an extension study of our previous report on mortality.

DOI: 10.1002/mds.26060
PubMed: 25447933


Affiliations:


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pubmed:25447933

Le document en format XML

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<nlm:affiliation>Department for Neurology, Medical University Innsbruck, Austria.</nlm:affiliation>
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<name sortKey="Diem Zangerl, Anja" sort="Diem Zangerl, Anja" uniqKey="Diem Zangerl A" first="Anja" last="Diem-Zangerl">Anja Diem-Zangerl</name>
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<name sortKey="Wenning, Gregor Karl" sort="Wenning, Gregor Karl" uniqKey="Wenning G" first="Gregor Karl" last="Wenning">Gregor Karl Wenning</name>
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<name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name>
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<term>Cardiovascular Diseases (mortality)</term>
<term>Cause of Death</term>
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<term>Follow-Up Studies</term>
<term>Humans</term>
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<div type="abstract" xml:lang="en">In this study we report on the outcome including overall and cause-specific mortality of Parkinson's disease (PD) patients subsequent to 38 years of surveillance. This is an extension study of our previous report on mortality.</div>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">In this study we report on the outcome including overall and cause-specific mortality of Parkinson's disease (PD) patients subsequent to 38 years of surveillance. This is an extension study of our previous report on mortality.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Two hundred thirty-seven patients with a symptom onset between 1974 and 1984 were followed until the date of December 31, 2012 or death, representing a follow-up period of up to 38 years. Overall and cause-specific standardized mortality ratios (SMRs) were calculated, and predictors for survival at disease onset were estimated.</AbstractText>
<AbstractText Label="RESULTS AND CONCLUSION" NlmCategory="CONCLUSIONS">Two hundred thirty patients had died by December 31, 2012; a total of 3,489 person-years were available for observation. The SMR at 38 years of follow-up was 2.02 (1.76-2.29). Employing Cox's proportional hazard modeling, male sex, gait disorder, absence of classical rest tremor, and absence of asymmetry predicted poor survival in this cohort. Increased cause-specific SMRs were found for pneumonia and cerebrovascular and cardiovascular diseases.</AbstractText>
<CopyrightInformation>© 2014 International Parkinson and Movement Disorder Society.</CopyrightInformation>
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