Mortality in Parkinson's disease: a 38-year follow-up study.
Identifieur interne : 000341 ( PubMed/Corpus ); précédent : 000340; suivant : 000342Mortality in Parkinson's disease: a 38-year follow-up study.
Auteurs : Bernadette Pinter ; Anja Diem-Zangerl ; Gregor Karl Wenning ; Christoph Scherfler ; Willi Oberaigner ; Klaus Seppi ; Werner PoeweSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
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- KwdEn :
- MESH :
Abstract
In this study we report on the outcome including overall and cause-specific mortality of Parkinson's disease (PD) patients subsequent to 38 years of surveillance. This is an extension study of our previous report on mortality.
DOI: 10.1002/mds.26060
PubMed: 25447933
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pubmed:25447933Le document en format XML
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<author><name sortKey="Pinter, Bernadette" sort="Pinter, Bernadette" uniqKey="Pinter B" first="Bernadette" last="Pinter">Bernadette Pinter</name>
<affiliation><nlm:affiliation>Department for Neurology, Medical University Innsbruck, Austria.</nlm:affiliation>
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<author><name sortKey="Diem Zangerl, Anja" sort="Diem Zangerl, Anja" uniqKey="Diem Zangerl A" first="Anja" last="Diem-Zangerl">Anja Diem-Zangerl</name>
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<author><name sortKey="Wenning, Gregor Karl" sort="Wenning, Gregor Karl" uniqKey="Wenning G" first="Gregor Karl" last="Wenning">Gregor Karl Wenning</name>
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<author><name sortKey="Scherfler, Christoph" sort="Scherfler, Christoph" uniqKey="Scherfler C" first="Christoph" last="Scherfler">Christoph Scherfler</name>
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<author><name sortKey="Oberaigner, Willi" sort="Oberaigner, Willi" uniqKey="Oberaigner W" first="Willi" last="Oberaigner">Willi Oberaigner</name>
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<author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name>
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<author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Mortality in Parkinson's disease: a 38-year follow-up study.</title>
<author><name sortKey="Pinter, Bernadette" sort="Pinter, Bernadette" uniqKey="Pinter B" first="Bernadette" last="Pinter">Bernadette Pinter</name>
<affiliation><nlm:affiliation>Department for Neurology, Medical University Innsbruck, Austria.</nlm:affiliation>
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<author><name sortKey="Diem Zangerl, Anja" sort="Diem Zangerl, Anja" uniqKey="Diem Zangerl A" first="Anja" last="Diem-Zangerl">Anja Diem-Zangerl</name>
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<author><name sortKey="Wenning, Gregor Karl" sort="Wenning, Gregor Karl" uniqKey="Wenning G" first="Gregor Karl" last="Wenning">Gregor Karl Wenning</name>
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<author><name sortKey="Scherfler, Christoph" sort="Scherfler, Christoph" uniqKey="Scherfler C" first="Christoph" last="Scherfler">Christoph Scherfler</name>
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<author><name sortKey="Oberaigner, Willi" sort="Oberaigner, Willi" uniqKey="Oberaigner W" first="Willi" last="Oberaigner">Willi Oberaigner</name>
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<author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name>
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<author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
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<term>Age of Onset</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Cardiovascular Diseases (mortality)</term>
<term>Cause of Death</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (mortality)</term>
<term>Proportional Hazards Models</term>
<term>Sex Factors</term>
<term>Tremor (mortality)</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Cardiovascular Diseases</term>
<term>Parkinson Disease</term>
<term>Tremor</term>
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<term>Age of Onset</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Cause of Death</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<front><div type="abstract" xml:lang="en">In this study we report on the outcome including overall and cause-specific mortality of Parkinson's disease (PD) patients subsequent to 38 years of surveillance. This is an extension study of our previous report on mortality.</div>
</front>
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<DateCreated><Year>2015</Year>
<Month>02</Month>
<Day>04</Day>
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<DateCompleted><Year>2015</Year>
<Month>10</Month>
<Day>22</Day>
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<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>30</Volume>
<Issue>2</Issue>
<PubDate><Year>2015</Year>
<Month>Feb</Month>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
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<ArticleTitle>Mortality in Parkinson's disease: a 38-year follow-up study.</ArticleTitle>
<Pagination><MedlinePgn>266-9</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.26060</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">In this study we report on the outcome including overall and cause-specific mortality of Parkinson's disease (PD) patients subsequent to 38 years of surveillance. This is an extension study of our previous report on mortality.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Two hundred thirty-seven patients with a symptom onset between 1974 and 1984 were followed until the date of December 31, 2012 or death, representing a follow-up period of up to 38 years. Overall and cause-specific standardized mortality ratios (SMRs) were calculated, and predictors for survival at disease onset were estimated.</AbstractText>
<AbstractText Label="RESULTS AND CONCLUSION" NlmCategory="CONCLUSIONS">Two hundred thirty patients had died by December 31, 2012; a total of 3,489 person-years were available for observation. The SMR at 38 years of follow-up was 2.02 (1.76-2.29). Employing Cox's proportional hazard modeling, male sex, gait disorder, absence of classical rest tremor, and absence of asymmetry predicted poor survival in this cohort. Increased cause-specific SMRs were found for pneumonia and cerebrovascular and cardiovascular diseases.</AbstractText>
<CopyrightInformation>© 2014 International Parkinson and Movement Disorder Society.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Pinter</LastName>
<ForeName>Bernadette</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department for Neurology, Medical University Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Diem-Zangerl</LastName>
<ForeName>Anja</ForeName>
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<Author ValidYN="Y"><LastName>Wenning</LastName>
<ForeName>Gregor Karl</ForeName>
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<Author ValidYN="Y"><LastName>Scherfler</LastName>
<ForeName>Christoph</ForeName>
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<Author ValidYN="Y"><LastName>Oberaigner</LastName>
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<Author ValidYN="Y"><LastName>Seppi</LastName>
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<Author ValidYN="Y"><LastName>Poewe</LastName>
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<Language>eng</Language>
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<ArticleDate DateType="Electronic"><Year>2014</Year>
<Month>12</Month>
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<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Mov Disord</MedlineTA>
<NlmUniqueID>8610688</NlmUniqueID>
<ISSNLinking>0885-3185</ISSNLinking>
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<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D017668">Age of Onset</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000401">mortality</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D016016">Proportional Hazards Models</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012737">Sex Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D014202">Tremor</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000401">mortality</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Parkinson's disease</Keyword>
<Keyword MajorTopicYN="N">SMR</Keyword>
<Keyword MajorTopicYN="N">cause-specific mortality</Keyword>
<Keyword MajorTopicYN="N">late stage</Keyword>
<Keyword MajorTopicYN="N">mortality</Keyword>
</KeywordList>
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