Movement Disorders (revue)

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The Non-Motor Manifestations of Dystonia: A Systematic Review

Identifieur interne : 000235 ( Pmc/Curation ); précédent : 000234; suivant : 000236

The Non-Motor Manifestations of Dystonia: A Systematic Review

Auteurs : Daniel J. Kuyper [États-Unis] ; Veronica Parra [États-Unis] ; Shanae Aerts [États-Unis] ; Michael S. Okun [États-Unis] ; Benzi M. Kluger [États-Unis]

Source :

RBID : PMC:3652664

Abstract

Non-motor symptoms are increasingly recognized as important determinants of quality of life and disability in a wide range of movement disorders. There is a limited body of research suggesting that many of these symptoms are also commonly associated with primary and other genetic forms of dystonia. However, the significance, etiology, pathophysiology, and treatment of these symptoms remains poorly described. The following is a review of the literature which focuses primarily on the association of these types of dystonia with psychiatric disorders, cognition, sleep, pain, and autonomic symptoms. We will also discuss potential mechanisms and approaches to treatment for non-motor features of dystonia.


Url:
DOI: 10.1002/mds.23709
PubMed: 21484874
PubMed Central: 3652664

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PMC:3652664

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<p id="P1">Non-motor symptoms are increasingly recognized as important determinants of quality of life and disability in a wide range of movement disorders. There is a limited body of research suggesting that many of these symptoms are also commonly associated with primary and other genetic forms of dystonia. However, the significance, etiology, pathophysiology, and treatment of these symptoms remains poorly described. The following is a review of the literature which focuses primarily on the association of these types of dystonia with psychiatric disorders, cognition, sleep, pain, and autonomic symptoms. We will also discuss potential mechanisms and approaches to treatment for non-motor features of dystonia.</p>
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