Psychiatric Symptoms Associated with Focal Hand Dystonia
Identifieur interne : 000227 ( Pmc/Curation ); précédent : 000226; suivant : 000228Psychiatric Symptoms Associated with Focal Hand Dystonia
Auteurs : Valerie Voon [Royaume-Uni, États-Unis] ; Tracy R. Butler [États-Unis] ; Vindhya Ekanayake [États-Unis] ; Cecile Gallea [États-Unis] ; Rezvan Ameli [États-Unis] ; Dennis L. Murphy [États-Unis] ; Mark Hallett [États-Unis]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2010.
Abstract
Myoclonus dystonia and idiopathic dystonia are associated with a greater frequency of obsessive compulsive disorder (OCD) and major depression. We investigated the frequency of OCD in 39 patients with primary focal hand dystonia (FHD) using a semistructured interview. OCD and subsyndromal OCD was diagnosed in 5 of 39 (12.82%) patients with FHD, whereas OCD occurs in 2.3% of the general population. Recurrent depression occurred in (7 of 39) 17.95% of patients with FHD along with a family history of depression in (16 of 39) 41.02%. Overlapping mechanisms manifesting as FHD may also predispose to OC symptoms and likely implicates a common striatal dysfunction.
Url:
DOI: 10.1002/mds.23250
PubMed: 20737548
PubMed Central: 4082988
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<front><div type="abstract" xml:lang="en"><p id="P1">Myoclonus dystonia and idiopathic dystonia are associated with a greater frequency of obsessive compulsive disorder (OCD) and major depression. We investigated the frequency of OCD in 39 patients with primary focal hand dystonia (FHD) using a semistructured interview. OCD and subsyndromal OCD was diagnosed in 5 of 39 (12.82%) patients with FHD, whereas OCD occurs in 2.3% of the general population. Recurrent depression occurred in (7 of 39) 17.95% of patients with FHD along with a family history of depression in (16 of 39) 41.02%. Overlapping mechanisms manifesting as FHD may also predispose to OC symptoms and likely implicates a common striatal dysfunction.</p>
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<given-names>Tracy R.</given-names>
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<aff id="A1"><label>1</label>
Behavioral and Clinical Neurosciences Institute, University of Cambridge, Cambridge, UK</aff>
<aff id="A2"><label>2</label>
National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA</aff>
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National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA</aff>
<author-notes><corresp id="cor1"><label>*</label>
Correspondence to: Valerie Voon, National Institutes of Health, 10 Center Drive, Bldg 10/Rm 7D37, Bethesda, MD. <email>voonv@gmail.com</email>
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<pub-date pub-type="nihms-submitted"><day>31</day>
<month>5</month>
<year>2014</year>
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<pub-date pub-type="ppub"><day>15</day>
<month>10</month>
<year>2010</year>
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<pub-date pub-type="pmc-release"><day>06</day>
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<permissions><copyright-statement>© 2010 Movement Disorder Society</copyright-statement>
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<abstract><p id="P1">Myoclonus dystonia and idiopathic dystonia are associated with a greater frequency of obsessive compulsive disorder (OCD) and major depression. We investigated the frequency of OCD in 39 patients with primary focal hand dystonia (FHD) using a semistructured interview. OCD and subsyndromal OCD was diagnosed in 5 of 39 (12.82%) patients with FHD, whereas OCD occurs in 2.3% of the general population. Recurrent depression occurred in (7 of 39) 17.95% of patients with FHD along with a family history of depression in (16 of 39) 41.02%. Overlapping mechanisms manifesting as FHD may also predispose to OC symptoms and likely implicates a common striatal dysfunction.</p>
</abstract>
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