Movement Disorders (revue)

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Is There an Increased Risk of Hip Fracture in Parkinson's Disease? A Nationwide Inpatient Sample

Identifieur interne : 002C41 ( PascalFrancis/Curation ); précédent : 002C40; suivant : 002C42

Is There an Increased Risk of Hip Fracture in Parkinson's Disease? A Nationwide Inpatient Sample

Auteurs : Rajib K. Bhattacharya [États-Unis] ; Richard M. Dubinsky [États-Unis] ; SUE MIN LAI [États-Unis] ; Hilary Dubinsky [États-Unis]

Source :

RBID : Pascal:12-0393086

Descripteurs français

English descriptors

Abstract

Objective: The aim of this study was to determine whether people with Parkinson's disease (PD) are overrepresented in a national cohort of hip-fracture admissions. Background: Frequent falls, combined with a higher rate of osteoporosis in people with PD, should lead to an increased risk of hip fracture. Methods: This work was a retrospective cohort analysis from the Nationwide Inpatient Sample from 1988 to 2007, a stratified sample of 20% of U.S. hospital admissions. Admissions with a primary diagnosis of acute hip fracture were identified, as was a subset with a secondary diagnosis of PD. Results: A total of 3.63% of 1,066,404 hip-fracture admissions had PD. When compared to the population of prevalence among patients with hip fracture, the prevalence of PD was up to 4.48 times (95% confidence interval [CI]: 4.46, 4.49) more than predicted, and when adjusted for gender and age, it was 4.02 (95% CI: 4.00, 4.03). Conclusions: In this 20-year nationwide sample of hip fractures, patients with PD were overrepresented by a factor of 4.
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A08 01  1  ENG  @1 Is There an Increased Risk of Hip Fracture in Parkinson's Disease? A Nationwide Inpatient Sample
A11 01  1    @1 BHATTACHARYA (Rajib K.)
A11 02  1    @1 DUBINSKY (Richard M.)
A11 03  1    @1 SUE MIN LAI
A11 04  1    @1 DUBINSKY (Hilary)
A14 01      @1 Department of Internal Medicine, Division of Endocrinology, Metabolism, and Genetics, University of Kansas Medical Center @2 Kansas City, Kansas @3 USA @Z 1 aut.
A14 02      @1 Department of Neurology, University of Kansas Medical Center @2 Kansas City, Kansas @3 USA @Z 2 aut. @Z 4 aut.
A14 03      @1 Department of Public Health and Preventive Medicine, University of Kansas Medical Center @2 Kansas City, Kansas @3 USA @Z 3 aut.
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A21       @1 2012
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A43 01      @1 INIST @2 20953 @5 354000502036870210
A44       @0 0000 @1 © 2012 INIST-CNRS. All rights reserved.
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A47 01  1    @0 12-0393086
A60       @1 P @3 CC
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C01 01    ENG  @0 Objective: The aim of this study was to determine whether people with Parkinson's disease (PD) are overrepresented in a national cohort of hip-fracture admissions. Background: Frequent falls, combined with a higher rate of osteoporosis in people with PD, should lead to an increased risk of hip fracture. Methods: This work was a retrospective cohort analysis from the Nationwide Inpatient Sample from 1988 to 2007, a stratified sample of 20% of U.S. hospital admissions. Admissions with a primary diagnosis of acute hip fracture were identified, as was a subset with a secondary diagnosis of PD. Results: A total of 3.63% of 1,066,404 hip-fracture admissions had PD. When compared to the population of prevalence among patients with hip fracture, the prevalence of PD was up to 4.48 times (95% confidence interval [CI]: 4.46, 4.49) more than predicted, and when adjusted for gender and age, it was 4.02 (95% CI: 4.00, 4.03). Conclusions: In this 20-year nationwide sample of hip fractures, patients with PD were overrepresented by a factor of 4.
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C03 01  X  FRE  @0 Fracture @5 01
C03 01  X  ENG  @0 Fracture @5 01
C03 01  X  SPA  @0 Fractura @5 01
C03 02  X  FRE  @0 Maladie de Parkinson @2 NM @5 02
C03 02  X  ENG  @0 Parkinson disease @2 NM @5 02
C03 02  X  SPA  @0 Parkinson enfermedad @2 NM @5 02
C03 03  X  FRE  @0 Ostéoporose @5 03
C03 03  X  ENG  @0 Osteoporosis @5 03
C03 03  X  SPA  @0 Osteoporosis @5 03
C03 04  X  FRE  @0 Pathologie du système nerveux @5 04
C03 04  X  ENG  @0 Nervous system diseases @5 04
C03 04  X  SPA  @0 Sistema nervioso patología @5 04
C03 05  X  FRE  @0 Facteur risque @5 09
C03 05  X  ENG  @0 Risk factor @5 09
C03 05  X  SPA  @0 Factor riesgo @5 09
C03 06  X  FRE  @0 Hanche @5 10
C03 06  X  ENG  @0 Hip @5 10
C03 06  X  SPA  @0 Cadera @5 10
C03 07  X  FRE  @0 Epidémiologie @5 11
C03 07  X  ENG  @0 Epidemiology @5 11
C03 07  X  SPA  @0 Epidemiología @5 11
C07 01  X  FRE  @0 Pathologie du système ostéoarticulaire @5 37
C07 01  X  ENG  @0 Diseases of the osteoarticular system @5 37
C07 01  X  SPA  @0 Sistema osteoarticular patología @5 37
C07 02  X  FRE  @0 Traumatisme @5 38
C07 02  X  ENG  @0 Trauma @5 38
C07 02  X  SPA  @0 Traumatismo @5 38
C07 03  X  FRE  @0 Pathologie de l'encéphale @5 39
C07 03  X  ENG  @0 Cerebral disorder @5 39
C07 03  X  SPA  @0 Encéfalo patología @5 39
C07 04  X  FRE  @0 Syndrome extrapyramidal @5 40
C07 04  X  ENG  @0 Extrapyramidal syndrome @5 40
C07 04  X  SPA  @0 Extrapiramidal síndrome @5 40
C07 05  X  FRE  @0 Maladie dégénérative @5 41
C07 05  X  ENG  @0 Degenerative disease @5 41
C07 05  X  SPA  @0 Enfermedad degenerativa @5 41
C07 06  X  FRE  @0 Pathologie du système nerveux central @5 42
C07 06  X  ENG  @0 Central nervous system disease @5 42
C07 06  X  SPA  @0 Sistema nervosio central patología @5 42
N21       @1 303
N44 01      @1 OTO
N82       @1 OTO

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Pascal:12-0393086

Le document en format XML

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<term>Nervous system diseases</term>
<term>Osteoporosis</term>
<term>Parkinson disease</term>
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<div type="abstract" xml:lang="en">Objective: The aim of this study was to determine whether people with Parkinson's disease (PD) are overrepresented in a national cohort of hip-fracture admissions. Background: Frequent falls, combined with a higher rate of osteoporosis in people with PD, should lead to an increased risk of hip fracture. Methods: This work was a retrospective cohort analysis from the Nationwide Inpatient Sample from 1988 to 2007, a stratified sample of 20% of U.S. hospital admissions. Admissions with a primary diagnosis of acute hip fracture were identified, as was a subset with a secondary diagnosis of PD. Results: A total of 3.63% of 1,066,404 hip-fracture admissions had PD. When compared to the population of prevalence among patients with hip fracture, the prevalence of PD was up to 4.48 times (95% confidence interval [CI]: 4.46, 4.49) more than predicted, and when adjusted for gender and age, it was 4.02 (95% CI: 4.00, 4.03). Conclusions: In this 20-year nationwide sample of hip fractures, patients with PD were overrepresented by a factor of 4.</div>
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<fC07 i1="06" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>42</s5>
</fC07>
<fN21>
<s1>303</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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