MovDisordV3, PascalFrancis, Curation, bibRecord, 002754

Milestones in Huntington Disease

Identifieur interne : 002754 ( PascalFrancis/Curation ); précédent : 002753; suivant : 002755

Milestones in Huntington Disease

Auteurs : Ira Shoulson [États-Unis] ; Anne B. Young [États-Unis]

Source :

Movement disorders [ 0885-3185 ] ; 2011.

RBID : Pascal:11-0264664

Descripteurs français

Pascal (Inist)
- Chorée de Huntington, Pathologie du système nerveux, Traitement.

English descriptors

KwdEn :
- Huntington disease, Nervous system diseases, Treatment.

Abstract

There have been extraordinary advances in our knowledge of the underlying gene, the protein it encodes, various models of disease, and potential targets for effective therapies for Huntington disease. Huntington disease research has increased exponentially in the past 25 years, and we now understand many of the molecular mechanisms underlying the disease. Still, more work needs to be done before we have a full understanding of the pathophysiology of the disease. Clinical research on biomarkers and clinical trials on potential neuroprotective agents are underway. Here we review our progress in these areas over the last 25 years and speculate on what the next 25 years may hold.

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C01	`01`		`ENG`	@0 There have been extraordinary advances in our knowledge of the underlying gene, the protein it encodes, various models of disease, and potential targets for effective therapies for Huntington disease. Huntington disease research has increased exponentially in the past 25 years, and we now understand many of the molecular mechanisms underlying the disease. Still, more work needs to be done before we have a full understanding of the pathophysiology of the disease. Clinical research on biomarkers and clinical trials on potential neuroprotective agents are underway. Here we review our progress in these areas over the last 25 years and speculate on what the next 25 years may hold.
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C03	`03`	`X`	`FRE`	`@0 Traitement @5 09`
C03	`03`	`X`	`ENG`	`@0 Treatment @5 09`
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C07	`03`	`X`	`ENG`	`@0 Degenerative disease @5 39`
C07	`03`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 39`
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C07	`05`	`X`	`FRE`	`@0 Pathologie du système nerveux central @5 41`
C07	`05`	`X`	`ENG`	`@0 Central nervous system disease @5 41`
C07	`05`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 41`
N21				`@1 178`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

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Le document en format XML

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	Movement Disorders (revue)
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Movement Disorders (revue)

Milestones in Huntington Disease

Milestones in Huntington Disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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