Movement Disorders (revue)

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Restless Legs Syndrome and Parkinson's Disease in Men

Identifieur interne : 002528 ( PascalFrancis/Curation ); précédent : 002527; suivant : 002529

Restless Legs Syndrome and Parkinson's Disease in Men

Auteurs : XIANG GAO [États-Unis] ; Michael A. Schwarzschild [États-Unis] ; Eilis J. O'Reilly [États-Unis] ; HAO WANG [États-Unis] ; Alberto Ascherio [États-Unis]

Source :

RBID : Pascal:10-0512958

Descripteurs français

English descriptors

Abstract

We examined whether men with restless legs syndrome (RLS) have a higher prevalence of Parkinson's disease (PD) among 23,119 US participants of the Health Professional Follow-up Study who were free of diabetes and arthritis. RLS was assessed using a set of standardized questions recommended by the International RLS Study Group. PD cases were identified by self-reported questionnaires and confirmed by review of medical records. Compared to men without RLS, multivariate-adjusted odds ratios for PD were 1.1 (95% confidence interval: 0.4, 3.0) for men with RLS symptoms 5-14 times per month and 3.09 (95% confidence interval: 1.5, 6.2; P trend = 0.003) for those with symptoms 15 times or more per month, after adjusting for age, smoking, use of anti-depressant, and other covariates. In conclusion, men with RLS are more likely to have concurrent PD. Prospective studies are warranted to clarify the temporal relationship between RLS and PD.
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A11 01  1    @1 XIANG GAO
A11 02  1    @1 SCHWARZSCHILD (Michael A.)
A11 03  1    @1 O'REILLY (Eilis J.)
A11 04  1    @1 HAO WANG
A11 05  1    @1 ASCHERIO (Alberto)
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C01 01    ENG  @0 We examined whether men with restless legs syndrome (RLS) have a higher prevalence of Parkinson's disease (PD) among 23,119 US participants of the Health Professional Follow-up Study who were free of diabetes and arthritis. RLS was assessed using a set of standardized questions recommended by the International RLS Study Group. PD cases were identified by self-reported questionnaires and confirmed by review of medical records. Compared to men without RLS, multivariate-adjusted odds ratios for PD were 1.1 (95% confidence interval: 0.4, 3.0) for men with RLS symptoms 5-14 times per month and 3.09 (95% confidence interval: 1.5, 6.2; P trend = 0.003) for those with symptoms 15 times or more per month, after adjusting for age, smoking, use of anti-depressant, and other covariates. In conclusion, men with RLS are more likely to have concurrent PD. Prospective studies are warranted to clarify the temporal relationship between RLS and PD.
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C03 01  X  FRE  @0 Syndrome des jambes sans repos @5 01
C03 01  X  ENG  @0 Restless legs syndrome @5 01
C03 01  X  SPA  @0 Acroparestesia nocturna @5 01
C03 02  X  FRE  @0 Maladie de Parkinson @2 NM @5 02
C03 02  X  ENG  @0 Parkinson disease @2 NM @5 02
C03 02  X  SPA  @0 Parkinson enfermedad @2 NM @5 02
C03 03  X  FRE  @0 Pathologie du système nerveux @5 03
C03 03  X  ENG  @0 Nervous system diseases @5 03
C03 03  X  SPA  @0 Sistema nervioso patología @5 03
C03 04  X  FRE  @0 Homme @5 09
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C07 01  X  FRE  @0 Trouble neurologique @5 38
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C07 01  X  SPA  @0 Trastorno neurológico @5 38
C07 02  X  FRE  @0 Trouble de la sensibilité @5 39
C07 02  X  ENG  @0 Sensitivity disorder @5 39
C07 02  X  SPA  @0 Trastorno sensibilidad @5 39
C07 03  X  FRE  @0 Pathologie de l'encéphale @5 40
C07 03  X  ENG  @0 Cerebral disorder @5 40
C07 03  X  SPA  @0 Encéfalo patología @5 40
C07 04  X  FRE  @0 Syndrome extrapyramidal @5 41
C07 04  X  ENG  @0 Extrapyramidal syndrome @5 41
C07 04  X  SPA  @0 Extrapiramidal síndrome @5 41
C07 05  X  FRE  @0 Maladie dégénérative @5 42
C07 05  X  ENG  @0 Degenerative disease @5 42
C07 05  X  SPA  @0 Enfermedad degenerativa @5 42
C07 06  X  FRE  @0 Pathologie du système nerveux central @5 43
C07 06  X  ENG  @0 Central nervous system disease @5 43
C07 06  X  SPA  @0 Sistema nervosio central patología @5 43
N21       @1 347
N44 01      @1 OTO
N82       @1 OTO

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Pascal:10-0512958

Le document en format XML

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<div type="abstract" xml:lang="en">We examined whether men with restless legs syndrome (RLS) have a higher prevalence of Parkinson's disease (PD) among 23,119 US participants of the Health Professional Follow-up Study who were free of diabetes and arthritis. RLS was assessed using a set of standardized questions recommended by the International RLS Study Group. PD cases were identified by self-reported questionnaires and confirmed by review of medical records. Compared to men without RLS, multivariate-adjusted odds ratios for PD were 1.1 (95% confidence interval: 0.4, 3.0) for men with RLS symptoms 5-14 times per month and 3.09 (95% confidence interval: 1.5, 6.2; P trend = 0.003) for those with symptoms 15 times or more per month, after adjusting for age, smoking, use of anti-depressant, and other covariates. In conclusion, men with RLS are more likely to have concurrent PD. Prospective studies are warranted to clarify the temporal relationship between RLS and PD.</div>
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<fC07 i1="01" i2="X" l="ENG">
<s0>Neurological disorder</s0>
<s5>38</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Trastorno neurológico</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Trouble de la sensibilité</s0>
<s5>39</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Sensitivity disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Trastorno sensibilidad</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Pathologie de l'encéphale</s0>
<s5>40</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>40</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Syndrome extrapyramidal</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Degenerative disease</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Pathologie du système nerveux central</s0>
<s5>43</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>43</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>43</s5>
</fC07>
<fN21>
<s1>347</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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