Excessive daytime sleepiness in de novo and treated Parkinson's disease
Identifieur interne : 002630 ( PascalFrancis/Corpus ); précédent : 002629; suivant : 002631Excessive daytime sleepiness in de novo and treated Parkinson's disease
Auteurs : Giovanni Fabbrini ; Piero Barbanti ; Cinzia Aurilia ; Nicola Vanacore ; Caterina Pauletti ; Giuseppe MecoSource :
- Movement disorders [ 0885-3185 ] ; 2002.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Excessive daytime sleepiness (EDS) in Parkinson's disease (PD) is due to either treatment-related factors or the disease itself. The study of this disturbing phenomenon in de novo parkinsonian patients may contribute to a better understanding of its pathophysiology. We conducted a case control study in which we compared 25 PD patients who had never been treated before with dopaminergic drugs (de novo PD), 50 PD patients being treated with dopaminergic drugs (treated PD), and 25 healthy control subjects, all of whom were matched for age and gender. EDS was measured by means of the Epworth Sleepiness Scale (ESS) and quality of sleep by means of the Pittsburgh Sleep Quality Index (PSQI). ESS and PSQI scores were not statistically different between de novo PD patients and controls, whereas they were significantly higher in treated PD. Differences in ESS score variability were best explained by the treatment effect, whereas there was no clear correlation between PSQI and any of the clinical variables considered.
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Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 02-0584326 INIST |
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ET : | Excessive daytime sleepiness in de novo and treated Parkinson's disease |
AU : | FABBRINI (Giovanni); BARBANTI (Piero); AURILIA (Cinzia); VANACORE (Nicola); PAULETTI (Caterina); MECO (Giuseppe) |
AF : | Department of Neurological Sciences, University La Sapienza/Rome/Italie (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2002; Vol. 17; No. 5; Pp. 1026-1030; Bibl. 29 ref. |
LA : | Anglais |
EA : | Excessive daytime sleepiness (EDS) in Parkinson's disease (PD) is due to either treatment-related factors or the disease itself. The study of this disturbing phenomenon in de novo parkinsonian patients may contribute to a better understanding of its pathophysiology. We conducted a case control study in which we compared 25 PD patients who had never been treated before with dopaminergic drugs (de novo PD), 50 PD patients being treated with dopaminergic drugs (treated PD), and 25 healthy control subjects, all of whom were matched for age and gender. EDS was measured by means of the Epworth Sleepiness Scale (ESS) and quality of sleep by means of the Pittsburgh Sleep Quality Index (PSQI). ESS and PSQI scores were not statistically different between de novo PD patients and controls, whereas they were significantly higher in treated PD. Differences in ESS score variability were best explained by the treatment effect, whereas there was no clear correlation between PSQI and any of the clinical variables considered. |
CC : | 002B17G |
FD : | Somnolence; Jour; De novo; Physiopathologie; Homme |
FG : | Trouble sommeil |
ED : | Somnolence; Day; De novo; Pathophysiology; Human |
EG : | Sleep disorder |
SD : | Somnolencia; Día; De novo; Fisiopatología; Hombre |
LO : | INIST-20953.354000105152380200 |
ID : | 02-0584326 |
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Pascal:02-0584326Le document en format XML
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