Movement Disorders (revue)

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Analysis of blink rate in patients with blepharospasm

Identifieur interne : 001A40 ( PascalFrancis/Corpus ); précédent : 001A39; suivant : 001A41

Analysis of blink rate in patients with blepharospasm

Auteurs : Anna Rita Bentivoglio ; Antonio Daniele ; Alberto Albanese ; Pietro Attilio Tonali ; Alfonso Fasano

Source :

RBID : Pascal:06-0435098

Descripteurs français

English descriptors

Abstract

The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern rest-BR higher than conversation-BR) in discriminating patients and controls were computed. The best fit was obtained with a rest-BR above 27 blinks per minute. When the two parameters were combined (rest-BR above 27 blinks per minute together with the pattern rest-BR higher than conversation-BR), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0885-3185
A03   1    @0 Mov. disord.
A05       @2 21
A06       @2 8
A08 01  1  ENG  @1 Analysis of blink rate in patients with blepharospasm
A11 01  1    @1 BENTIVOGLIO (Anna Rita)
A11 02  1    @1 DANIELE (Antonio)
A11 03  1    @1 ALBANESE (Alberto)
A11 04  1    @1 TONALI (Pietro Attilio)
A11 05  1    @1 FASANO (Alfonso)
A14 01      @1 Istituto di Neurologia, Università Cattolica del Sacro Cuore @2 Roma @3 ITA @Z 1 aut. @Z 2 aut. @Z 4 aut. @Z 5 aut.
A14 02      @1 Istituto Nazionale Neurologico Carlo Besta @2 Milano @3 ITA @Z 3 aut.
A14 03      @1 Fondazione Don Carlo Gnocchi @2 Milano @3 ITA @Z 4 aut.
A20       @1 1225-1229
A21       @1 2006
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000142193570290
A44       @0 0000 @1 © 2006 INIST-CNRS. All rights reserved.
A45       @0 15 ref.
A47 01  1    @0 06-0435098
A60       @1 P @3 CC
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern rest-BR higher than conversation-BR) in discriminating patients and controls were computed. The best fit was obtained with a rest-BR above 27 blinks per minute. When the two parameters were combined (rest-BR above 27 blinks per minute together with the pattern rest-BR higher than conversation-BR), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages.
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C03 01  X  FRE  @0 Système nerveux pathologie @5 01
C03 01  X  ENG  @0 Nervous system diseases @5 01
C03 01  X  SPA  @0 Sistema nervioso patología @5 01
C03 02  X  FRE  @0 Blépharospasme @5 02
C03 02  X  ENG  @0 Blepharospasm @5 02
C03 02  X  SPA  @0 Blefaroespasmo @5 02
C03 03  X  FRE  @0 Dystonie @5 03
C03 03  X  ENG  @0 Dystonia @5 03
C03 03  X  SPA  @0 Distonía @5 03
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C03 04  X  ENG  @0 Human @5 09
C03 04  X  SPA  @0 Hombre @5 09
C03 05  X  FRE  @0 Clignement palpébral @5 10
C03 05  X  ENG  @0 Blinking @5 10
C03 05  X  SPA  @0 Parpadeo @5 10
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C07 01  X  SPA  @0 Ojo patología @5 37
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C07 02  X  ENG  @0 Eyelid disease @5 38
C07 02  X  SPA  @0 Párpado patología @5 38
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C07 03  X  ENG  @0 Extrapyramidal syndrome @5 39
C07 03  X  SPA  @0 Extrapiramidal síndrome @5 39
C07 04  X  FRE  @0 Mouvement involontaire @5 40
C07 04  X  ENG  @0 Involuntary movement @5 40
C07 04  X  SPA  @0 Movimiento involuntario @5 40
C07 05  X  FRE  @0 Muscle strié pathologie @5 41
C07 05  X  ENG  @0 Striated muscle disease @5 41
C07 05  X  SPA  @0 Músculo estriado patología @5 41
C07 06  X  FRE  @0 Trouble neurologique @5 42
C07 06  X  ENG  @0 Neurological disorder @5 42
C07 06  X  SPA  @0 Trastorno neurológico @5 42
C07 07  X  FRE  @0 Encéphale pathologie @5 43
C07 07  X  ENG  @0 Cerebral disorder @5 43
C07 07  X  SPA  @0 Encéfalo patología @5 43
C07 08  X  FRE  @0 Système nerveux central pathologie @5 44
C07 08  X  ENG  @0 Central nervous system disease @5 44
C07 08  X  SPA  @0 Sistema nervosio central patología @5 44
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Format Inist (serveur)

NO : PASCAL 06-0435098 INIST
ET : Analysis of blink rate in patients with blepharospasm
AU : BENTIVOGLIO (Anna Rita); DANIELE (Antonio); ALBANESE (Alberto); TONALI (Pietro Attilio); FASANO (Alfonso)
AF : Istituto di Neurologia, Università Cattolica del Sacro Cuore/Roma/Italie (1 aut., 2 aut., 4 aut., 5 aut.); Istituto Nazionale Neurologico Carlo Besta/Milano/Italie (3 aut.); Fondazione Don Carlo Gnocchi/Milano/Italie (4 aut.)
DT : Publication en série; Courte communication, note brève; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2006; Vol. 21; No. 8; Pp. 1225-1229; Bibl. 15 ref.
LA : Anglais
EA : The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern rest-BR higher than conversation-BR) in discriminating patients and controls were computed. The best fit was obtained with a rest-BR above 27 blinks per minute. When the two parameters were combined (rest-BR above 27 blinks per minute together with the pattern rest-BR higher than conversation-BR), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages.
CC : 002B17; 002B17F; 002B16B
FD : Système nerveux pathologie; Blépharospasme; Dystonie; Homme; Clignement palpébral
FG : Oeil pathologie; Paupière pathologie; Extrapyramidal syndrome; Mouvement involontaire; Muscle strié pathologie; Trouble neurologique; Encéphale pathologie; Système nerveux central pathologie
ED : Nervous system diseases; Blepharospasm; Dystonia; Human; Blinking
EG : Eye disease; Eyelid disease; Extrapyramidal syndrome; Involuntary movement; Striated muscle disease; Neurological disorder; Cerebral disorder; Central nervous system disease
SD : Sistema nervioso patología; Blefaroespasmo; Distonía; Hombre; Parpadeo
LO : INIST-20953.354000142193570290
ID : 06-0435098

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Pascal:06-0435098

Le document en format XML

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<div type="abstract" xml:lang="en">The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern rest-BR higher than conversation-BR) in discriminating patients and controls were computed. The best fit was obtained with a rest-BR above 27 blinks per minute. When the two parameters were combined (rest-BR above 27 blinks per minute together with the pattern rest-BR higher than conversation-BR), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages.</div>
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<fC07 i1="01" i2="X" l="SPA">
<s0>Ojo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Paupière pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Eyelid disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Párpado patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Extrapyramidal syndrome</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Mouvement involontaire</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Involuntary movement</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Movimiento involuntario</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Muscle strié pathologie</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Striated muscle disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Músculo estriado patología</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Trouble neurologique</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Neurological disorder</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Trastorno neurológico</s0>
<s5>42</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE">
<s0>Encéphale pathologie</s0>
<s5>43</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>43</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>43</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE">
<s0>Système nerveux central pathologie</s0>
<s5>44</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>44</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>44</s5>
</fC07>
<fN21>
<s1>289</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
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<server>
<NO>PASCAL 06-0435098 INIST</NO>
<ET>Analysis of blink rate in patients with blepharospasm</ET>
<AU>BENTIVOGLIO (Anna Rita); DANIELE (Antonio); ALBANESE (Alberto); TONALI (Pietro Attilio); FASANO (Alfonso)</AU>
<AF>Istituto di Neurologia, Università Cattolica del Sacro Cuore/Roma/Italie (1 aut., 2 aut., 4 aut., 5 aut.); Istituto Nazionale Neurologico Carlo Besta/Milano/Italie (3 aut.); Fondazione Don Carlo Gnocchi/Milano/Italie (4 aut.)</AF>
<DT>Publication en série; Courte communication, note brève; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2006; Vol. 21; No. 8; Pp. 1225-1229; Bibl. 15 ref.</SO>
<LA>Anglais</LA>
<EA>The blink rate (BR) during rest, conversation, and reading was assessed in 50 patients with blepharospasm (BS) and in 150 healthy subjects. BR at rest and during conversation was higher in patients with BS. Moreover, 76% of patients had BR higher at rest than during conversation, whereas in 74% of controls, BR was higher during conversation than at rest. The sensitivity and specificity of two parameters (value of BR at rest and pattern rest-BR higher than conversation-BR) in discriminating patients and controls were computed. The best fit was obtained with a rest-BR above 27 blinks per minute. When the two parameters were combined (rest-BR above 27 blinks per minute together with the pattern rest-BR higher than conversation-BR), we obtained a 92.3% sensitivity and a 82.0% specificity in discriminating between BS patients and controls. These findings indicate that specific features of BR can be associated with BS, suggesting that the analysis of BR might be helpful for the diagnosis of BS in early stages.</EA>
<CC>002B17; 002B17F; 002B16B</CC>
<FD>Système nerveux pathologie; Blépharospasme; Dystonie; Homme; Clignement palpébral</FD>
<FG>Oeil pathologie; Paupière pathologie; Extrapyramidal syndrome; Mouvement involontaire; Muscle strié pathologie; Trouble neurologique; Encéphale pathologie; Système nerveux central pathologie</FG>
<ED>Nervous system diseases; Blepharospasm; Dystonia; Human; Blinking</ED>
<EG>Eye disease; Eyelid disease; Extrapyramidal syndrome; Involuntary movement; Striated muscle disease; Neurological disorder; Cerebral disorder; Central nervous system disease</EG>
<SD>Sistema nervioso patología; Blefaroespasmo; Distonía; Hombre; Parpadeo</SD>
<LO>INIST-20953.354000142193570290</LO>
<ID>06-0435098</ID>
</server>
</inist>
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