MovDisordV3, PascalFrancis, Corpus, bibRecord, 001607

Manganic encephalopathy due to "ephedrone" abuse

Identifieur interne : 001607 ( PascalFrancis/Corpus ); précédent : 001606; suivant : 001608

Manganic encephalopathy due to "ephedrone" abuse

Auteurs : Yanush Sanotsky ; Roman Lesyk ; Lyudmyla Fedoryshyn ; Iryna Komnatska ; Yuriy Matviyenko ; Stanley Fahn

Source :

Movement disorders [ 0885-3185 ] ; 2007.

RBID : Pascal:07-0391089

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Encéphalopathie, Parkinsonisme, Toxicomanie, Abus, Manganèse, Intoxication.

English descriptors

KwdEn :
- Abuse, Drug addiction, Encephalopathy, Manganese, Nervous system diseases, Parkinsonism, Poisoning.

Abstract

We describe the clinical and neuroimaging features of 6 drug-abuse patients with self-inflicted manganese poisoning. The patients injected a home-brewed mixture called "ephedrone" (slang term) that contained manganese to produce an amphetamine-like euphoria. The desired chemical product, phenylpropanoneamine (also called methcathinone), was synthesized from a common-cold-remedy compound using permanganate as the catalyst. Manganese was a by-product in the ephedrone mixture. After months of self-injections, a clinical picture emerged, consisting of apathy, bradykinesia, gait disorder with postural instability, and spastic-hypokinetic dysarthria. There was no response to levodopa. The MRI revealed symmetric hyperintense T1-weighted signals in the basal ganglia, typical of manganese accumulation.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A03		`1`		`@0 Mov. disord.`
A05				`@2 22`
A06				`@2 9`
A08	`01`	`1`	`ENG`	`@1 Manganic encephalopathy due to "ephedrone" abuse`
A11	`01`	`1`		`@1 SANOTSKY (Yanush)`
A11	`02`	`1`		`@1 LESYK (Roman)`
A11	`03`	`1`		`@1 FEDORYSHYN (Lyudmyla)`
A11	`04`	`1`		`@1 KOMNATSKA (Iryna)`
A11	`05`	`1`		`@1 MATVIYENKO (Yuriy)`
A11	`06`	`1`		`@1 FAHN (Stanley)`
A14	`01`			`@1 Department of Neurology, Lviv Regional Clinical Hospital @2 Lviv @3 UKR @Z 1 aut. @Z 3 aut.`
A14	`02`			`@1 Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University @2 Lviv @3 UKR @Z 2 aut.`
A14	`03`			`@1 Department of MRI, Central Hospital of the Lviv Regional Railway @2 Lviv @3 UKR @Z 4 aut.`
A14	`04`			`@1 Department of Neurology, Danylo Halytsky Lviv National Medical University @2 Lviv @3 UKR @Z 5 aut.`
A14	`05`			`@1 Department of Neurology, Columbia University Medical Center @2 New York, New York @3 USA @Z 6 aut.`
A20				`@1 1337-1343`
A21				`@1 2007`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20953 @5 354000146732490220`
A44				`@0 0000 @1 © 2007 INIST-CNRS. All rights reserved.`
A45				`@0 33 ref.`
A47	`01`	`1`		`@0 07-0391089`
A60				`@1 P @3 CC`
A61				`@0 A`
A64	`01`	`1`		`@0 Movement disorders`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 We describe the clinical and neuroimaging features of 6 drug-abuse patients with self-inflicted manganese poisoning. The patients injected a home-brewed mixture called "ephedrone" (slang term) that contained manganese to produce an amphetamine-like euphoria. The desired chemical product, phenylpropanoneamine (also called methcathinone), was synthesized from a common-cold-remedy compound using permanganate as the catalyst. Manganese was a by-product in the ephedrone mixture. After months of self-injections, a clinical picture emerged, consisting of apathy, bradykinesia, gait disorder with postural instability, and spastic-hypokinetic dysarthria. There was no response to levodopa. The MRI revealed symmetric hyperintense T1-weighted signals in the basal ganglia, typical of manganese accumulation.
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C02	`02`	`X`		`@0 002B05C02A`
C02	`03`	`X`		`@0 002B13C02`
C03	`01`	`X`	`FRE`	`@0 Système nerveux pathologie @5 01`
C03	`01`	`X`	`ENG`	`@0 Nervous system diseases @5 01`
C03	`01`	`X`	`SPA`	`@0 Sistema nervioso patología @5 01`
C03	`02`	`X`	`FRE`	`@0 Encéphalopathie @5 02`
C03	`02`	`X`	`ENG`	`@0 Encephalopathy @5 02`
C03	`02`	`X`	`SPA`	`@0 Encefalopatía @5 02`
C03	`03`	`X`	`FRE`	`@0 Parkinsonisme @2 NM @5 03`
C03	`03`	`X`	`ENG`	`@0 Parkinsonism @2 NM @5 03`
C03	`03`	`X`	`SPA`	`@0 Parkinson síndrome @2 NM @5 03`
C03	`04`	`X`	`FRE`	`@0 Toxicomanie @5 04`
C03	`04`	`X`	`ENG`	`@0 Drug addiction @5 04`
C03	`04`	`X`	`SPA`	`@0 Toxicomanía @5 04`
C03	`05`	`X`	`FRE`	`@0 Abus @5 09`
C03	`05`	`X`	`ENG`	`@0 Abuse @5 09`
C03	`05`	`X`	`SPA`	`@0 Abuso @5 09`
C03	`06`	`X`	`FRE`	`@0 Manganèse @2 NC @5 10`
C03	`06`	`X`	`ENG`	`@0 Manganese @2 NC @5 10`
C03	`06`	`X`	`SPA`	`@0 Manganeso @2 NC @5 10`
C03	`07`	`X`	`FRE`	`@0 Intoxication @5 11`
C03	`07`	`X`	`ENG`	`@0 Poisoning @5 11`
C03	`07`	`X`	`SPA`	`@0 Intoxicación @5 11`
C07	`01`	`X`	`FRE`	`@0 Encéphale pathologie @5 37`
C07	`01`	`X`	`ENG`	`@0 Cerebral disorder @5 37`
C07	`01`	`X`	`SPA`	`@0 Encéfalo patología @5 37`
C07	`02`	`X`	`FRE`	`@0 Système nerveux central pathologie @5 38`
C07	`02`	`X`	`ENG`	`@0 Central nervous system disease @5 38`
C07	`02`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 38`
N21				`@1 253`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 07-0391089 INIST
ET :	Manganic encephalopathy due to "ephedrone" abuse
AU :	SANOTSKY (Yanush); LESYK (Roman); FEDORYSHYN (Lyudmyla); KOMNATSKA (Iryna); MATVIYENKO (Yuriy); FAHN (Stanley)
AF :	Department of Neurology, Lviv Regional Clinical Hospital/Lviv/Ukraine (1 aut., 3 aut.); Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University/Lviv/Ukraine (2 aut.); Department of MRI, Central Hospital of the Lviv Regional Railway/Lviv/Ukraine (4 aut.); Department of Neurology, Danylo Halytsky Lviv National Medical University/Lviv/Ukraine (5 aut.); Department of Neurology, Columbia University Medical Center/New York, New York/Etats-Unis (6 aut.)
DT :	Publication en série; Courte communication, note brève; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 9; Pp. 1337-1343; Bibl. 33 ref.
LA :	Anglais
EA :	We describe the clinical and neuroimaging features of 6 drug-abuse patients with self-inflicted manganese poisoning. The patients injected a home-brewed mixture called "ephedrone" (slang term) that contained manganese to produce an amphetamine-like euphoria. The desired chemical product, phenylpropanoneamine (also called methcathinone), was synthesized from a common-cold-remedy compound using permanganate as the catalyst. Manganese was a by-product in the ephedrone mixture. After months of self-injections, a clinical picture emerged, consisting of apathy, bradykinesia, gait disorder with postural instability, and spastic-hypokinetic dysarthria. There was no response to levodopa. The MRI revealed symmetric hyperintense T1-weighted signals in the basal ganglia, typical of manganese accumulation.
CC :	002B17; 002B05C02A; 002B13C02
FD :	Système nerveux pathologie; Encéphalopathie; Parkinsonisme; Toxicomanie; Abus; Manganèse; Intoxication
FG :	Encéphale pathologie; Système nerveux central pathologie
ED :	Nervous system diseases; Encephalopathy; Parkinsonism; Drug addiction; Abuse; Manganese; Poisoning
EG :	Cerebral disorder; Central nervous system disease
SD :	Sistema nervioso patología; Encefalopatía; Parkinson síndrome; Toxicomanía; Abuso; Manganeso; Intoxicación
LO :	INIST-20953.354000146732490220
ID :	07-0391089

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Pascal:07-0391089

Le document en format XML

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<front><div type="abstract" xml:lang="en">We describe the clinical and neuroimaging features of 6 drug-abuse patients with self-inflicted manganese poisoning. The patients injected a home-brewed mixture called "ephedrone" (slang term) that contained manganese to produce an amphetamine-like euphoria. The desired chemical product, phenylpropanoneamine (also called methcathinone), was synthesized from a common-cold-remedy compound using permanganate as the catalyst. Manganese was a by-product in the ephedrone mixture. After months of self-injections, a clinical picture emerged, consisting of apathy, bradykinesia, gait disorder with postural instability, and spastic-hypokinetic dysarthria. There was no response to levodopa. The MRI revealed symmetric hyperintense T1-weighted signals in the basal ganglia, typical of manganese accumulation.</div>
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<fC01 i1="01" l="ENG"><s0>We describe the clinical and neuroimaging features of 6 drug-abuse patients with self-inflicted manganese poisoning. The patients injected a home-brewed mixture called "ephedrone" (slang term) that contained manganese to produce an amphetamine-like euphoria. The desired chemical product, phenylpropanoneamine (also called methcathinone), was synthesized from a common-cold-remedy compound using permanganate as the catalyst. Manganese was a by-product in the ephedrone mixture. After months of self-injections, a clinical picture emerged, consisting of apathy, bradykinesia, gait disorder with postural instability, and spastic-hypokinetic dysarthria. There was no response to levodopa. The MRI revealed symmetric hyperintense T1-weighted signals in the basal ganglia, typical of manganese accumulation.</s0>
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<server><NO>PASCAL 07-0391089 INIST</NO>
<ET>Manganic encephalopathy due to "ephedrone" abuse</ET>
<AU>SANOTSKY (Yanush); LESYK (Roman); FEDORYSHYN (Lyudmyla); KOMNATSKA (Iryna); MATVIYENKO (Yuriy); FAHN (Stanley)</AU>
<AF>Department of Neurology, Lviv Regional Clinical Hospital/Lviv/Ukraine (1 aut., 3 aut.); Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University/Lviv/Ukraine (2 aut.); Department of MRI, Central Hospital of the Lviv Regional Railway/Lviv/Ukraine (4 aut.); Department of Neurology, Danylo Halytsky Lviv National Medical University/Lviv/Ukraine (5 aut.); Department of Neurology, Columbia University Medical Center/New York, New York/Etats-Unis (6 aut.)</AF>
<DT>Publication en série; Courte communication, note brève; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 9; Pp. 1337-1343; Bibl. 33 ref.</SO>
<LA>Anglais</LA>
<EA>We describe the clinical and neuroimaging features of 6 drug-abuse patients with self-inflicted manganese poisoning. The patients injected a home-brewed mixture called "ephedrone" (slang term) that contained manganese to produce an amphetamine-like euphoria. The desired chemical product, phenylpropanoneamine (also called methcathinone), was synthesized from a common-cold-remedy compound using permanganate as the catalyst. Manganese was a by-product in the ephedrone mixture. After months of self-injections, a clinical picture emerged, consisting of apathy, bradykinesia, gait disorder with postural instability, and spastic-hypokinetic dysarthria. There was no response to levodopa. The MRI revealed symmetric hyperintense T1-weighted signals in the basal ganglia, typical of manganese accumulation.</EA>
<CC>002B17; 002B05C02A; 002B13C02</CC>
<FD>Système nerveux pathologie; Encéphalopathie; Parkinsonisme; Toxicomanie; Abus; Manganèse; Intoxication</FD>
<FG>Encéphale pathologie; Système nerveux central pathologie</FG>
<ED>Nervous system diseases; Encephalopathy; Parkinsonism; Drug addiction; Abuse; Manganese; Poisoning</ED>
<EG>Cerebral disorder; Central nervous system disease</EG>
<SD>Sistema nervioso patología; Encefalopatía; Parkinson síndrome; Toxicomanía; Abuso; Manganeso; Intoxicación</SD>
<LO>INIST-20953.354000146732490220</LO>
<ID>07-0391089</ID>
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Movement Disorders (revue)

Manganic encephalopathy due to "ephedrone" abuse

Manganic encephalopathy due to "ephedrone" abuse

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