Movement Disorders (revue)

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Lower urinary tract symptoms and bladder control in advanced Parkinson's disease : Effects of deep brain stimulation in the subthalamic nucleus

Identifieur interne : 001604 ( PascalFrancis/Checkpoint ); précédent : 001603; suivant : 001605

Lower urinary tract symptoms and bladder control in advanced Parkinson's disease : Effects of deep brain stimulation in the subthalamic nucleus

Auteurs : Kristian Winge [Danemark] ; Kurt Kr Yer Nielsen [Danemark] ; Hans Stimpel [Danemark] ; Annemette Lokkegaard [Danemark] ; Steen Rusborg Jensen [Danemark] ; Lene Werdelin [Danemark]

Source :

RBID : Pascal:07-0133247

Descripteurs français

English descriptors

Abstract

Deep brain stimulation in the subthalamic nucleus (STN) leads to significant improvement in motor function in patients with advanced Parkinson's disease (PD). In this prospective study including 16 patients with PD, we investigated (1) lower urinary tract symptoms (LUTS) by questionnaires International Prostate Symptom Score (IPSS, symptoms only) and Danish Prostate Symptom Score (DanPSS, symptoms and bother of symptoms) and (2) bladder control (assessed by urodynamics) before and after implantation of electrodes in the STN. PD symptoms (Unified Parkinson's Disease Rating Scale score) improved significantly (P < 0.0001), and symptoms of overactive bladder (IPSS) decreased along with the troublesome symptoms of overactive bladder (DanPSS; P < 0.01 for both). Urodynamic parameters before and after implantation of electrodes in the STN, evaluated with and without the stimulation on, did not change significantly.


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Pascal:07-0133247

Le document en format XML

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<div type="abstract" xml:lang="en">Deep brain stimulation in the subthalamic nucleus (STN) leads to significant improvement in motor function in patients with advanced Parkinson's disease (PD). In this prospective study including 16 patients with PD, we investigated (1) lower urinary tract symptoms (LUTS) by questionnaires International Prostate Symptom Score (IPSS, symptoms only) and Danish Prostate Symptom Score (DanPSS, symptoms and bother of symptoms) and (2) bladder control (assessed by urodynamics) before and after implantation of electrodes in the STN. PD symptoms (Unified Parkinson's Disease Rating Scale score) improved significantly (P < 0.0001), and symptoms of overactive bladder (IPSS) decreased along with the troublesome symptoms of overactive bladder (DanPSS; P < 0.01 for both). Urodynamic parameters before and after implantation of electrodes in the STN, evaluated with and without the stimulation on, did not change significantly.</div>
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<s5>44</s5>
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<fC07 i1="08" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>44</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE">
<s0>Système nerveux central</s0>
<s5>45</s5>
</fC07>
<fC07 i1="09" i2="X" l="ENG">
<s0>Central nervous system</s0>
<s5>45</s5>
</fC07>
<fC07 i1="09" i2="X" l="SPA">
<s0>Sistema nervioso central</s0>
<s5>45</s5>
</fC07>
<fN21>
<s1>085</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
<affiliations>
<list>
<country>
<li>Danemark</li>
</country>
<region>
<li>Hovedstaden</li>
</region>
<settlement>
<li>Copenhague</li>
</settlement>
</list>
<tree>
<country name="Danemark">
<region name="Hovedstaden">
<name sortKey="Winge, Kristian" sort="Winge, Kristian" uniqKey="Winge K" first="Kristian" last="Winge">Kristian Winge</name>
</region>
<name sortKey="Jensen, Steen Rusborg" sort="Jensen, Steen Rusborg" uniqKey="Jensen S" first="Steen Rusborg" last="Jensen">Steen Rusborg Jensen</name>
<name sortKey="Lokkegaard, Annemette" sort="Lokkegaard, Annemette" uniqKey="Lokkegaard A" first="Annemette" last="Lokkegaard">Annemette Lokkegaard</name>
<name sortKey="Nielsen, Kurt Kr Yer" sort="Nielsen, Kurt Kr Yer" uniqKey="Nielsen K" first="Kurt Kr Yer" last="Nielsen">Kurt Kr Yer Nielsen</name>
<name sortKey="Stimpel, Hans" sort="Stimpel, Hans" uniqKey="Stimpel H" first="Hans" last="Stimpel">Hans Stimpel</name>
<name sortKey="Werdelin, Lene" sort="Werdelin, Lene" uniqKey="Werdelin L" first="Lene" last="Werdelin">Lene Werdelin</name>
</country>
</tree>
</affiliations>
</record>

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