MovDisordV3, PascalFrancis, Checkpoint, bibRecord, 001259

Excessive Dopamine Neuron Loss in Progressive Supranuclear Palsy

Identifieur interne : 001259 ( PascalFrancis/Checkpoint ); précédent : 001258; suivant : 001260

Excessive Dopamine Neuron Loss in Progressive Supranuclear Palsy

Auteurs : Karen E. Murphy [Australie] ; Tanya Karaconji [Australie] ; Craig D. Hardman [Australie] ; Glenda M. Halliday [Australie]

Source :

Movement disorders [ 0885-3185 ] ; 2008.

RBID : Pascal:08-0199373

Descripteurs français

Pascal (Inist)
- Maladie de Parkinson, Pathologie du système nerveux, Dopamine, Mort cellulaire, Mésencéphale, Neurone.

English descriptors

KwdEn :
- Cell death, Dopamine, Midbrain, Nervous system diseases, Neuron, Parkinson disease.

Abstract

Progressive supranuclear palsy (PSP) and Parkinson's disease (PD) differ in their response to dopaminergic replacement therapies, despite having a similar degree of neuronal degeneration in the dopaminergic substantia nigra. We observed more widespread dopamine neuron loss in the extranigral A10 midbrain cell groups in PSP compared with PD. These cell groups innervate subcortical and cortical regions and may be required for adequate response to levodopa therapy.

Affiliations:

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Le document en format XML

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	Movement Disorders (revue)
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Movement Disorders (revue)

Excessive Dopamine Neuron Loss in Progressive Supranuclear Palsy

Excessive Dopamine Neuron Loss in Progressive Supranuclear Palsy

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri