Characteristics of the Sequence Effect in Parkinson's Disease
Identifieur interne : 000B64 ( PascalFrancis/Checkpoint ); précédent : 000B63; suivant : 000B65Characteristics of the Sequence Effect in Parkinson's Disease
Auteurs : Suk Yun Kang [États-Unis, Corée du Sud] ; Toshiaki Wasaka [États-Unis] ; Ejaz A. Shamim [États-Unis] ; Sungyoung Auh [États-Unis] ; Yoshino Ueki [États-Unis] ; Grisel J. Lopez [États-Unis] ; Tetsuo Kida [États-Unis] ; Seung-Hyun Jin [États-Unis] ; Nguyet Dang [États-Unis] ; Mark Hallett [États-Unis]Source :
- Movement disorders [ 0885-3185 ] ; 2010.
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Abstract
The sequence effect (SE) in Parkinson's disease (PD) is progressive slowing of sequential movements. It is a feature of bradykinesia, but is separate from a general slowness without deterioration over time. It is commonly seen in PD, but its physiology is unclear. We measured general slowness and the SE separately with a computer-based, modified Purdue pegboard in 11 patients with advanced PD. We conducted a placebo-controlled. four-way crossover study to learn whether levodopa and repetitive transcranial magnetic stimulation (rTMS) could improve general slowness or the SE. We also examined the correlation between the SE and clinical fatigue. Levodopa alone and rTMS alone improved general slowness, but rTMS showed no additive effect on levodopa. Levodopa alone, rTMS alone, and their combination did not alleviate the SE. There was no correlation between the SE and fatigue. This study suggests that dopaminergic dysfunction and abnormal motor cortex excitability are not the relevant mechanisms for the SE. Additionally, the SE is not a component of clinical fatigue. Further work is needed to establish the physiology and clinical relevance of the SE.
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Characteristics of the Sequence Effect in Parkinson's Disease</title><author><name sortKey="Yun Kang, Suk" sort="Yun Kang, Suk" uniqKey="Yun Kang S" first="Suk" last="Yun Kang">Suk Yun Kang</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Neurology, Kang-Nam Sacred Heart Hospital, Hallym University College of Medicine</s1><s2>Seoul</s2><s3>KOR</s3><sZ>1 aut.</sZ></inist:fA14><country>Corée du Sud</country><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Wasaka, Toshiaki" sort="Wasaka, Toshiaki" uniqKey="Wasaka T" first="Toshiaki" last="Wasaka">Toshiaki Wasaka</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Shamim, Ejaz A" sort="Shamim, Ejaz A" uniqKey="Shamim E" first="Ejaz A." last="Shamim">Ejaz A. 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Lopez</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kida, Tetsuo" sort="Kida, Tetsuo" uniqKey="Kida T" first="Tetsuo" last="Kida">Tetsuo Kida</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 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type="wicri:source">INIST</idno><idno type="inist">10-0474354</idno><date when="2010">2010</date><idno type="stanalyst">PASCAL 10-0474354 INIST</idno><idno type="RBID">Pascal:10-0474354</idno><idno type="wicri:Area/PascalFrancis/Corpus">000875</idno><idno type="wicri:Area/PascalFrancis/Curation">002444</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000B64</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Characteristics of the Sequence Effect in Parkinson's Disease</title><author><name sortKey="Yun Kang, Suk" sort="Yun Kang, Suk" uniqKey="Yun Kang S" first="Suk" last="Yun Kang">Suk Yun Kang</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Neurology, Kang-Nam Sacred Heart Hospital, Hallym University College of Medicine</s1><s2>Seoul</s2><s3>KOR</s3><sZ>1 aut.</sZ></inist:fA14><country>Corée du Sud</country><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Wasaka, Toshiaki" sort="Wasaka, Toshiaki" uniqKey="Wasaka T" first="Toshiaki" last="Wasaka">Toshiaki Wasaka</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Shamim, Ejaz A" sort="Shamim, Ejaz A" uniqKey="Shamim E" first="Ejaz A." last="Shamim">Ejaz A. Shamim</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Kaiser Permanente Midatlantic Permanente Medical Group</s1><s2>Suitland, Maryland</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Auh, Sungyoung" sort="Auh, Sungyoung" uniqKey="Auh S" first="Sungyoung" last="Auh">Sungyoung Auh</name><affiliation wicri:level="2"><inist:fA14 i1="04"><s1>Clinical Neurosciences Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Ueki, Yoshino" sort="Ueki, Yoshino" uniqKey="Ueki Y" first="Yoshino" last="Ueki">Yoshino Ueki</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Lopez, Grisel J" sort="Lopez, Grisel J" uniqKey="Lopez G" first="Grisel J." last="Lopez">Grisel J. Lopez</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kida, Tetsuo" sort="Kida, Tetsuo" uniqKey="Kida T" first="Tetsuo" last="Kida">Tetsuo Kida</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Jin, Seung Hyun" sort="Jin, Seung Hyun" uniqKey="Jin S" first="Seung-Hyun" last="Jin">Seung-Hyun Jin</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Dang, Nguyet" sort="Dang, Nguyet" uniqKey="Dang N" first="Nguyet" last="Dang">Nguyet Dang</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hallett, Mark" sort="Hallett, Mark" uniqKey="Hallett M" first="Mark" last="Hallett">Mark Hallett</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Fatigue</term><term>Levodopa</term><term>Nervous system diseases</term><term>Parkinson disease</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term><term>Pathologie du système nerveux</term><term>Fatigue</term><term>Lévodopa</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The sequence effect (SE) in Parkinson's disease (PD) is progressive slowing of sequential movements. It is a feature of bradykinesia, but is separate from a general slowness without deterioration over time. It is commonly seen in PD, but its physiology is unclear. We measured general slowness and the SE separately with a computer-based, modified Purdue pegboard in 11 patients with advanced PD. We conducted a placebo-controlled. four-way crossover study to learn whether levodopa and repetitive transcranial magnetic stimulation (rTMS) could improve general slowness or the SE. We also examined the correlation between the SE and clinical fatigue. Levodopa alone and rTMS alone improved general slowness, but rTMS showed no additive effect on levodopa. Levodopa alone, rTMS alone, and their combination did not alleviate the SE. There was no correlation between the SE and fatigue. This study suggests that dopaminergic dysfunction and abnormal motor cortex excitability are not the relevant mechanisms for the SE. Additionally, the SE is not a component of clinical fatigue. Further work is needed to establish the physiology and clinical relevance of the SE.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0885-3185</s0></fA01><fA03 i2="1"><s0>Mov. disord.</s0></fA03><fA05><s2>25</s2></fA05><fA06><s2>13</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Characteristics of the Sequence Effect in Parkinson's Disease</s1></fA08><fA11 i1="01" i2="1"><s1>YUN KANG (Suk)</s1></fA11><fA11 i1="02" i2="1"><s1>WASAKA (Toshiaki)</s1></fA11><fA11 i1="03" i2="1"><s1>SHAMIM (Ejaz A.)</s1></fA11><fA11 i1="04" i2="1"><s1>AUH (Sungyoung)</s1></fA11><fA11 i1="05" i2="1"><s1>UEKI (Yoshino)</s1></fA11><fA11 i1="06" i2="1"><s1>LOPEZ (Grisel J.)</s1></fA11><fA11 i1="07" i2="1"><s1>KIDA (Tetsuo)</s1></fA11><fA11 i1="08" i2="1"><s1>JIN (Seung-Hyun)</s1></fA11><fA11 i1="09" i2="1"><s1>DANG (Nguyet)</s1></fA11><fA11 i1="10" i2="1"><s1>HALLETT (Mark)</s1></fA11><fA14 i1="01"><s1>Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></fA14><fA14 i1="02"><s1>Department of Neurology, Kang-Nam Sacred Heart Hospital, Hallym University College of Medicine</s1><s2>Seoul</s2><s3>KOR</s3><sZ>1 aut.</sZ></fA14><fA14 i1="03"><s1>Kaiser Permanente Midatlantic Permanente Medical Group</s1><s2>Suitland, Maryland</s2><s3>USA</s3><sZ>3 aut.</sZ></fA14><fA14 i1="04"><s1>Clinical Neurosciences Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health</s1><s2>Bethesda, Maryland</s2><s3>USA</s3><sZ>4 aut.</sZ></fA14><fA20><s1>2148-2155</s1></fA20><fA21><s1>2010</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>20953</s2><s5>354000193258110200</s5></fA43><fA44><s0>0000</s0><s1>© 2010 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>57 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>10-0474354</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Movement disorders</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>The sequence effect (SE) in Parkinson's disease (PD) is progressive slowing of sequential movements. It is a feature of bradykinesia, but is separate from a general slowness without deterioration over time. It is commonly seen in PD, but its physiology is unclear. We measured general slowness and the SE separately with a computer-based, modified Purdue pegboard in 11 patients with advanced PD. We conducted a placebo-controlled. four-way crossover study to learn whether levodopa and repetitive transcranial magnetic stimulation (rTMS) could improve general slowness or the SE. We also examined the correlation between the SE and clinical fatigue. Levodopa alone and rTMS alone improved general slowness, but rTMS showed no additive effect on levodopa. Levodopa alone, rTMS alone, and their combination did not alleviate the SE. There was no correlation between the SE and fatigue. This study suggests that dopaminergic dysfunction and abnormal motor cortex excitability are not the relevant mechanisms for the SE. Additionally, the SE is not a component of clinical fatigue. Further work is needed to establish the physiology and clinical relevance of the SE.</s0></fC01><fC02 i1="01" i2="X"><s0>002B17</s0></fC02><fC02 i1="02" i2="X"><s0>002B17G</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Maladie de Parkinson</s0><s2>NM</s2><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Parkinson disease</s0><s2>NM</s2><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Parkinson enfermedad</s0><s2>NM</s2><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Pathologie du système nerveux</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Nervous system diseases</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Sistema nervioso patología</s0><s5>02</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Fatigue</s0><s5>09</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Fatigue</s0><s5>09</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Fatiga</s0><s5>09</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Lévodopa</s0><s2>NK</s2><s2>FR</s2><s5>10</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Levodopa</s0><s2>NK</s2><s2>FR</s2><s5>10</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Levodopa</s0><s2>NK</s2><s2>FR</s2><s5>10</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Pathologie de l'encéphale</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Cerebral disorder</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Encéfalo patología</s0><s5>37</s5></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Syndrome extrapyramidal</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0><s5>38</s5></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Maladie dégénérative</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Degenerative disease</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0><s5>39</s5></fC07><fC07 i1="04" i2="X" l="FRE"><s0>Pathologie du système nerveux central</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0><s5>40</s5></fC07><fN21><s1>312</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard></inist><affiliations><list><country><li>Corée du Sud</li><li>États-Unis</li></country><region><li>Maryland</li></region><settlement><li>Séoul</li></settlement></list><tree><country name="États-Unis"><region name="Maryland"><name sortKey="Yun Kang, Suk" sort="Yun Kang, Suk" uniqKey="Yun Kang S" first="Suk" last="Yun Kang">Suk Yun Kang</name></region><name sortKey="Auh, Sungyoung" sort="Auh, Sungyoung" uniqKey="Auh S" first="Sungyoung" last="Auh">Sungyoung Auh</name><name sortKey="Dang, Nguyet" sort="Dang, Nguyet" uniqKey="Dang N" first="Nguyet" last="Dang">Nguyet Dang</name><name sortKey="Hallett, Mark" sort="Hallett, Mark" uniqKey="Hallett M" first="Mark" last="Hallett">Mark Hallett</name><name sortKey="Jin, Seung Hyun" sort="Jin, Seung Hyun" uniqKey="Jin S" first="Seung-Hyun" last="Jin">Seung-Hyun Jin</name><name sortKey="Kida, Tetsuo" sort="Kida, Tetsuo" uniqKey="Kida T" first="Tetsuo" last="Kida">Tetsuo Kida</name><name sortKey="Lopez, Grisel J" sort="Lopez, Grisel J" uniqKey="Lopez G" first="Grisel J." last="Lopez">Grisel J. Lopez</name><name sortKey="Shamim, Ejaz A" sort="Shamim, Ejaz A" uniqKey="Shamim E" first="Ejaz A." last="Shamim">Ejaz A. Shamim</name><name sortKey="Shamim, Ejaz A" sort="Shamim, Ejaz A" uniqKey="Shamim E" first="Ejaz A." last="Shamim">Ejaz A. Shamim</name><name sortKey="Ueki, Yoshino" sort="Ueki, Yoshino" uniqKey="Ueki Y" first="Yoshino" last="Ueki">Yoshino Ueki</name><name sortKey="Wasaka, Toshiaki" sort="Wasaka, Toshiaki" uniqKey="Wasaka T" first="Toshiaki" last="Wasaka">Toshiaki Wasaka</name></country><country name="Corée du Sud"><noRegion><name sortKey="Yun Kang, Suk" sort="Yun Kang, Suk" uniqKey="Yun Kang S" first="Suk" last="Yun Kang">Suk Yun Kang</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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