Severe constipation in Parkinson's disease relieved by botulinum toxin.
Identifieur interne : 004D90 ( Ncbi/Merge ); précédent : 004D89; suivant : 004D91Severe constipation in Parkinson's disease relieved by botulinum toxin.
Auteurs : A. Albanese [Italie] ; G. Maria ; A R Bentivoglio ; G. Brisinda ; E. Cassetta ; P. TonaliSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1997.
English descriptors
- KwdEn :
- Anti-Dyskinesia Agents (therapeutic use), Botulinum Toxins, Type A (therapeutic use), Constipation (drug therapy), Constipation (etiology), Constipation (physiopathology), Constipation (radiography), Follow-Up Studies, Humans, Injections, Intramuscular, Male, Middle Aged, Parkinson Disease (complications), Parkinson Disease (physiopathology), Recurrence.
- MESH :
- chemical , therapeutic use : Anti-Dyskinesia Agents, Botulinum Toxins, Type A.
- complications : Parkinson Disease.
- drug therapy : Constipation.
- etiology : Constipation.
- physiopathology : Constipation, Parkinson Disease.
- radiography : Constipation.
- Follow-Up Studies, Humans, Injections, Intramuscular, Male, Middle Aged, Recurrence.
Abstract
A parkinsonian patient with severe outlet-type constipation was treated with injection of botulinum toxin into the puborectalis muscle. A total of 30 units (Botox) was injected in two sites. Resting anal pressure, maximum voluntary contraction, and pressure on straining were evaluated before treatment and 4, 8, 12, and 16 weeks afterward. Pressure values declined following treatment, the decline of pressure on straining ending by week 12. Proctography performed 8 weeks after treatment showed improvement in the anorectal angle and evacuation of barium paste. The clinical benefit lasted for approximately 12 weeks. The present data show that botulinum toxin is a promising tool for treating outlet-type constipation in Parkinson's disease.
DOI: 10.1002/mds.870120524
PubMed: 9380063
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pubmed:9380063Le document en format XML
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Maria</name></author><author><name sortKey="Bentivoglio, A R" sort="Bentivoglio, A R" uniqKey="Bentivoglio A" first="A R" last="Bentivoglio">A R Bentivoglio</name></author><author><name sortKey="Brisinda, G" sort="Brisinda, G" uniqKey="Brisinda G" first="G" last="Brisinda">G. Brisinda</name></author><author><name sortKey="Cassetta, E" sort="Cassetta, E" uniqKey="Cassetta E" first="E" last="Cassetta">E. Cassetta</name></author><author><name sortKey="Tonali, P" sort="Tonali, P" uniqKey="Tonali P" first="P" last="Tonali">P. 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A total of 30 units (Botox) was injected in two sites. Resting anal pressure, maximum voluntary contraction, and pressure on straining were evaluated before treatment and 4, 8, 12, and 16 weeks afterward. Pressure values declined following treatment, the decline of pressure on straining ending by week 12. Proctography performed 8 weeks after treatment showed improvement in the anorectal angle and evacuation of barium paste. The clinical benefit lasted for approximately 12 weeks. The present data show that botulinum toxin is a promising tool for treating outlet-type constipation in Parkinson's disease.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">9380063</PMID><DateCreated><Year>1997</Year><Month>11</Month><Day>07</Day></DateCreated><DateCompleted><Year>1997</Year><Month>11</Month><Day>07</Day></DateCompleted><DateRevised><Year>2010</Year><Month>11</Month><Day>18</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN><JournalIssue CitedMedium="Print"><Volume>12</Volume><Issue>5</Issue><PubDate><Year>1997</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Severe constipation in Parkinson's disease relieved by botulinum toxin.</ArticleTitle><Pagination><MedlinePgn>764-6</MedlinePgn></Pagination><Abstract><AbstractText>A parkinsonian patient with severe outlet-type constipation was treated with injection of botulinum toxin into the puborectalis muscle. A total of 30 units (Botox) was injected in two sites. Resting anal pressure, maximum voluntary contraction, and pressure on straining were evaluated before treatment and 4, 8, 12, and 16 weeks afterward. Pressure values declined following treatment, the decline of pressure on straining ending by week 12. Proctography performed 8 weeks after treatment showed improvement in the anorectal angle and evacuation of barium paste. The clinical benefit lasted for approximately 12 weeks. The present data show that botulinum toxin is a promising tool for treating outlet-type constipation in Parkinson's disease.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Albanese</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute of Neurology, Sacro Cuore Catholic University, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maria</LastName><ForeName>G</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Bentivoglio</LastName><ForeName>A R</ForeName><Initials>AR</Initials></Author><Author ValidYN="Y"><LastName>Brisinda</LastName><ForeName>G</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Cassetta</LastName><ForeName>E</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Tonali</LastName><ForeName>P</ForeName><Initials>P</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>UNITED STATES</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D018726">Anti-Dyskinesia Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.4.24.69</RegistryNumber><NameOfSubstance UI="D019274">Botulinum Toxins, Type A</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D018726">Anti-Dyskinesia Agents</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D019274">Botulinum Toxins, Type A</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D003248">Constipation</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000188">drug therapy</QualifierName><QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000530">radiography</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005500">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D007273">Injections, Intramuscular</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000150">complications</QualifierName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012008">Recurrence</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1997</Year><Month>9</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1997</Year><Month>9</Month><Day>26</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1997</Year><Month>9</Month><Day>26</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">9380063</ArticleId><ArticleId IdType="doi">10.1002/mds.870120524</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Italie</li></country><region><li>Latium</li></region><settlement><li>Rome</li></settlement></list><tree><noCountry><name sortKey="Bentivoglio, A R" sort="Bentivoglio, A R" uniqKey="Bentivoglio A" first="A R" last="Bentivoglio">A R Bentivoglio</name><name sortKey="Brisinda, G" sort="Brisinda, G" uniqKey="Brisinda G" first="G" last="Brisinda">G. Brisinda</name><name sortKey="Cassetta, E" sort="Cassetta, E" uniqKey="Cassetta E" first="E" last="Cassetta">E. Cassetta</name><name sortKey="Maria, G" sort="Maria, G" uniqKey="Maria G" first="G" last="Maria">G. Maria</name><name sortKey="Tonali, P" sort="Tonali, P" uniqKey="Tonali P" first="P" last="Tonali">P. Tonali</name></noCountry><country name="Italie"><region name="Latium"><name sortKey="Albanese, A" sort="Albanese, A" uniqKey="Albanese A" first="A" last="Albanese">A. Albanese</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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