MovDisordV3, Ncbi, Merge, bibRecord, 001C84

Effect of Age on Geriatric Depression Scale Performance in Parkinson’s Disease

Identifieur interne : 001C84 ( Ncbi/Merge ); précédent : 001C83; suivant : 001C85

Effect of Age on Geriatric Depression Scale Performance in Parkinson’s Disease

Auteurs : Daniel Weintraub [États-Unis] ; Kirsten Saboe [États-Unis] ; Matthew B. Stern [États-Unis]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2007.

RBID : PMC:2000798

English descriptors

KwdEn :
- Age Factors, Aged, Aged, 80 and over, Analysis of Variance, Depression (diagnosis), Depression (etiology), Diagnostic and Statistical Manual of Mental Disorders, Female, Geriatric Assessment, Humans, Male, Middle Aged, Parkinson Disease (complications), ROC Curve, Severity of Illness Index.
MESH :
- complications : Parkinson Disease.
- diagnosis : Depression.
- etiology : Depression.
- Age Factors, Aged, Aged, 80 and over, Analysis of Variance, Diagnostic and Statistical Manual of Mental Disorders, Female, Geriatric Assessment, Humans, Male, Middle Aged, ROC Curve, Severity of Illness Index.

Abstract

The purpose of this study was to compare the validity of the 15-item Geriatric Depression Scale (GDS-15) in nonelderly (<65 years), young-elderly (age, 65-75), and old-elderly (>75 years) patients with Parkinson’s disease (PD). 57 nonelderly, 88 young-elderly, and 81 old-elderly PD patients were administered the GDS-15 and the Structured Clinical Interview for DSM-IV depression module. Receiver-operating characteristic (ROC) curves were plotted for GDS-15 scores against a DSM-IV diagnosis of major or minor depression. The discriminant validity of the GDS-15 was high for nonelderly, young-elderly, and oldelderly subjects (ROC area under curve = 0.92, 0.91, and 0.95, respectively), with optimal dichotomization at a cut-off of 4/5 (85% sensitivity and 84% specificity in nonelderly; 89% sensitivity and 82% specificity in young-elderly) and 5/6 (90% sensitivity and 90% specificity in old-elderly). In conclusion, the GDS-15 has comparable validity in younger and older PD patients, suggesting its appropriateness as a depression screening instrument in PD patients of all ages.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000798

DOI: 10.1002/mds.21369
PubMed: 17546674
PubMed Central: 2000798

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PMC:2000798

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p id="P2">The purpose of this study was to compare the validity of the 15-item Geriatric Depression Scale (GDS-15) in nonelderly (<65 years), young-elderly (age, 65-75), and old-elderly (>75 years) patients with Parkinson’s disease (PD). 57 nonelderly, 88 young-elderly, and 81 old-elderly PD patients were administered the GDS-15 and the Structured Clinical Interview for DSM-IV depression module. Receiver-operating characteristic (ROC) curves were plotted for GDS-15 scores against a DSM-IV diagnosis of major or minor depression. The discriminant validity of the GDS-15 was high for nonelderly, young-elderly, and oldelderly subjects (ROC area under curve = 0.92, 0.91, and 0.95, respectively), with optimal dichotomization at a cut-off of 4/5 (85% sensitivity and 84% specificity in nonelderly; 89% sensitivity and 82% specificity in young-elderly) and 5/6 (90% sensitivity and 90% specificity in old-elderly). In conclusion, the GDS-15 has comparable validity in younger and older PD patients, suggesting its appropriateness as a depression screening instrument in PD patients of all ages.</p>
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<date when="2007">2007</date>
<idno type="doi">10.1002/mds.21369</idno>
<idno type="RBID">pubmed:17546674</idno>
<idno type="pmid">17546674</idno>
<idno type="wicri:Area/PubMed/Corpus">002655</idno>
<idno type="wicri:Area/PubMed/Curation">002655</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002845</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Effect of age on geriatric depression scale performance in Parkinson's disease.</title>
<author><name sortKey="Weintraub, Daniel" sort="Weintraub, Daniel" uniqKey="Weintraub D" first="Daniel" last="Weintraub">Daniel Weintraub</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA. weintrau@mail.med.upenn.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Saboe, Kirsten" sort="Saboe, Kirsten" uniqKey="Saboe K" first="Kirsten" last="Saboe">Kirsten Saboe</name>
</author>
<author><name sortKey="Stern, Matthew B" sort="Stern, Matthew B" uniqKey="Stern M" first="Matthew B" last="Stern">Matthew B. Stern</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2007" type="published">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age Factors</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Analysis of Variance</term>
<term>Depression (diagnosis)</term>
<term>Depression (etiology)</term>
<term>Diagnostic and Statistical Manual of Mental Disorders</term>
<term>Female</term>
<term>Geriatric Assessment</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (complications)</term>
<term>ROC Curve</term>
<term>Severity of Illness Index</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Depression</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Depression</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Age Factors</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Analysis of Variance</term>
<term>Diagnostic and Statistical Manual of Mental Disorders</term>
<term>Female</term>
<term>Geriatric Assessment</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>ROC Curve</term>
<term>Severity of Illness Index</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The purpose of this study was to compare the validity of the 15-item Geriatric Depression Scale (GDS-15) in nonelderly (<65 years), young-elderly (age, 65-75), and old-elderly (>75 years) patients with Parkinson's disease (PD). 57 nonelderly, 88 young-elderly, and 81 old-elderly PD patients were administered the GDS-15 and the Structured Clinical Interview for DSM-IV depression module. Receiver-operating characteristic (ROC) curves were plotted for GDS-15 scores against a DSM-IV diagnosis of major or minor depression. The discriminant validity of the GDS-15 was high for nonelderly, young-elderly, and old-elderly subjects (ROC area under curve = 0.92, 0.91, and 0.95, respectively), with optimal dichotomization at a cut-off of 4/5 (85% sensitivity and 84% specificity in nonelderly; 89% sensitivity and 82% specificity in young-elderly) and 5/6 (90% sensitivity and 90% specificity in old-elderly). In conclusion, the GDS-15 has comparable validity in younger and older PD patients, suggesting its appropriateness as a depression screening instrument in PD patients of all ages.</div>
</front>
</TEI>
</pubmed>
</double>
</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Effect of Age on Geriatric Depression Scale Performance in Parkinson’s Disease

Effect of Age on Geriatric Depression Scale Performance in Parkinson’s Disease

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