Idiosyncratic adverse reactions to intramuscular botulinum toxin type A injection.
Identifieur interne : 004E43 ( Ncbi/Curation ); précédent : 004E42; suivant : 004E44Idiosyncratic adverse reactions to intramuscular botulinum toxin type A injection.
Auteurs : P A Lewitt [États-Unis] ; R M TroschSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1997.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Botulinum Toxins, Type A.
- chemical , adverse effects : Botulinum Toxins, Type A.
- drug therapy : Dystonia, Torticollis, Tremor.
- etiology : Exanthema.
- Adult, Aged, Female, Humans, Hypersensitivity, Injections, Intramuscular, Middle Aged.
Abstract
Three cases of adverse reactions to repeated intramuscular botulinum toxin A (BTA) injections are described: a persistent rash on the face at the site of injection, a localized anaphylactic reaction following BTA injection into one leg, and bilateral ptosis repeatedly following BTA injection into neck muscles. The mechanisms for these idiosyncratic adverse responses are not known.
DOI: 10.1002/mds.870120637
PubMed: 9399239
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pubmed:9399239Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Idiosyncratic adverse reactions to intramuscular botulinum toxin type A injection.</title>
<author><name sortKey="Lewitt, P A" sort="Lewitt, P A" uniqKey="Lewitt P" first="P A" last="Lewitt">P A Lewitt</name>
<affiliation wicri:level="2"><nlm:affiliation>Clinical Neuroscience Center, Sinai Hospital, West Bloomfield, Michigan, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Clinical Neuroscience Center, Sinai Hospital, West Bloomfield, Michigan</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trosch, R M" sort="Trosch, R M" uniqKey="Trosch R" first="R M" last="Trosch">R M Trosch</name>
</author>
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<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1997">1997</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Idiosyncratic adverse reactions to intramuscular botulinum toxin type A injection.</title>
<author><name sortKey="Lewitt, P A" sort="Lewitt, P A" uniqKey="Lewitt P" first="P A" last="Lewitt">P A Lewitt</name>
<affiliation wicri:level="2"><nlm:affiliation>Clinical Neuroscience Center, Sinai Hospital, West Bloomfield, Michigan, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Clinical Neuroscience Center, Sinai Hospital, West Bloomfield, Michigan</wicri:regionArea>
<placeName><region type="state">Michigan</region>
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<author><name sortKey="Trosch, R M" sort="Trosch, R M" uniqKey="Trosch R" first="R M" last="Trosch">R M Trosch</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="1997" type="published">1997</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Botulinum Toxins, Type A (administration & dosage)</term>
<term>Botulinum Toxins, Type A (adverse effects)</term>
<term>Dystonia (drug therapy)</term>
<term>Exanthema (etiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Hypersensitivity</term>
<term>Injections, Intramuscular</term>
<term>Middle Aged</term>
<term>Torticollis (drug therapy)</term>
<term>Tremor (drug therapy)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Botulinum Toxins, Type A</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Botulinum Toxins, Type A</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Dystonia</term>
<term>Torticollis</term>
<term>Tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Exanthema</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Hypersensitivity</term>
<term>Injections, Intramuscular</term>
<term>Middle Aged</term>
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<front><div type="abstract" xml:lang="en">Three cases of adverse reactions to repeated intramuscular botulinum toxin A (BTA) injections are described: a persistent rash on the face at the site of injection, a localized anaphylactic reaction following BTA injection into one leg, and bilateral ptosis repeatedly following BTA injection into neck muscles. The mechanisms for these idiosyncratic adverse responses are not known.</div>
</front>
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