Basal ganglia physiology and deep brain stimulation.
Identifieur interne : 002A70 ( Ncbi/Curation ); précédent : 002A69; suivant : 002A71Basal ganglia physiology and deep brain stimulation.
Auteurs : Andres M. Lozano [Canada] ; Brian J. Snyder ; Clement Hamani ; William D. Hutchison ; Jonathan O. DostrovskySource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2010.
English descriptors
- KwdEn :
- MESH :
- methods : Deep Brain Stimulation.
- pathology : Basal Ganglia, Parkinson Disease.
- physiology : Action Potentials, Basal Ganglia, Neurons.
- therapy : Parkinson Disease.
- Animals, Humans.
Abstract
Despite improvements in anatomic imaging of the basal ganglia, microelectrode recording is still an invaluable tool in locating appropriate targets for neurosurgical intervention. These recording also provide an unparalleled opportunity to study the pathophysiological aspects of diseases. This article reviews the principles of microelectrode recording in functional neurosurgery and discusses the pathologic neurophysiologic findings commonly encountered. It also highlights some of the potential mechanisms of action of both dopaminergic drugs and deep brain stimulation. In addition we review the recent work on pedunculopontine nucleus neurophysiology and trials of deep brain stimulation in that region for gait disturbances in Parkinson's disease.
DOI: 10.1002/mds.22714
PubMed: 20187251
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001932
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :001932
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001A23
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :002A70
Links to Exploration step
pubmed:20187251Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Basal ganglia physiology and deep brain stimulation.</title>
<author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, UHN, Toronto, Ontario, Canada. lozano@uhnres.utoronto.ca</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, UHN, Toronto, Ontario</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Snyder, Brian J" sort="Snyder, Brian J" uniqKey="Snyder B" first="Brian J" last="Snyder">Brian J. Snyder</name>
</author>
<author><name sortKey="Hamani, Clement" sort="Hamani, Clement" uniqKey="Hamani C" first="Clement" last="Hamani">Clement Hamani</name>
</author>
<author><name sortKey="Hutchison, William D" sort="Hutchison, William D" uniqKey="Hutchison W" first="William D" last="Hutchison">William D. Hutchison</name>
</author>
<author><name sortKey="Dostrovsky, Jonathan O" sort="Dostrovsky, Jonathan O" uniqKey="Dostrovsky J" first="Jonathan O" last="Dostrovsky">Jonathan O. Dostrovsky</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2010">2010</date>
<idno type="doi">10.1002/mds.22714</idno>
<idno type="RBID">pubmed:20187251</idno>
<idno type="pmid">20187251</idno>
<idno type="wicri:Area/PubMed/Corpus">001932</idno>
<idno type="wicri:Area/PubMed/Curation">001932</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001A23</idno>
<idno type="wicri:Area/Ncbi/Merge">002A70</idno>
<idno type="wicri:Area/Ncbi/Curation">002A70</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Basal ganglia physiology and deep brain stimulation.</title>
<author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, UHN, Toronto, Ontario, Canada. lozano@uhnres.utoronto.ca</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, UHN, Toronto, Ontario</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Snyder, Brian J" sort="Snyder, Brian J" uniqKey="Snyder B" first="Brian J" last="Snyder">Brian J. Snyder</name>
</author>
<author><name sortKey="Hamani, Clement" sort="Hamani, Clement" uniqKey="Hamani C" first="Clement" last="Hamani">Clement Hamani</name>
</author>
<author><name sortKey="Hutchison, William D" sort="Hutchison, William D" uniqKey="Hutchison W" first="William D" last="Hutchison">William D. Hutchison</name>
</author>
<author><name sortKey="Dostrovsky, Jonathan O" sort="Dostrovsky, Jonathan O" uniqKey="Dostrovsky J" first="Jonathan O" last="Dostrovsky">Jonathan O. Dostrovsky</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2010" type="published">2010</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Action Potentials (physiology)</term>
<term>Animals</term>
<term>Basal Ganglia (pathology)</term>
<term>Basal Ganglia (physiology)</term>
<term>Deep Brain Stimulation (methods)</term>
<term>Humans</term>
<term>Neurons (physiology)</term>
<term>Parkinson Disease (pathology)</term>
<term>Parkinson Disease (therapy)</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Deep Brain Stimulation</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Basal Ganglia</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Action Potentials</term>
<term>Basal Ganglia</term>
<term>Neurons</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Humans</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Despite improvements in anatomic imaging of the basal ganglia, microelectrode recording is still an invaluable tool in locating appropriate targets for neurosurgical intervention. These recording also provide an unparalleled opportunity to study the pathophysiological aspects of diseases. This article reviews the principles of microelectrode recording in functional neurosurgery and discusses the pathologic neurophysiologic findings commonly encountered. It also highlights some of the potential mechanisms of action of both dopaminergic drugs and deep brain stimulation. In addition we review the recent work on pedunculopontine nucleus neurophysiology and trials of deep brain stimulation in that region for gait disturbances in Parkinson's disease.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002A70 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 002A70 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Ncbi |étape= Curation |type= RBID |clé= pubmed:20187251 |texte= Basal ganglia physiology and deep brain stimulation. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:20187251" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a MovDisordV3
![]() | This area was generated with Dilib version V0.6.23. | ![]() |