Sulpiride-induced tardive dystonia.
Identifieur interne : 002784 ( Ncbi/Curation ); précédent : 002783; suivant : 002785Sulpiride-induced tardive dystonia.
Auteurs : L G Miller [États-Unis] ; Joseph Jankovic [États-Unis]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1990.
English descriptors
- KwdEn :
- Adult, Antipsychotic Agents (adverse effects), Antipsychotic Agents (therapeutic use), Dyskinesia, Drug-Induced (etiology), Dystonia (chemically induced), Humans, Male, Psychotic Disorders (drug therapy), Receptors, Dopamine (drug effects), Receptors, Dopamine D2, Sulpiride (adverse effects), Sulpiride (therapeutic use).
- MESH :
- chemical , adverse effects : Antipsychotic Agents, Sulpiride.
- chemical , drug effects : Receptors, Dopamine.
- chemical , therapeutic use : Antipsychotic Agents, Sulpiride.
- chemically induced : Dystonia.
- drug therapy : Psychotic Disorders.
- etiology : Dyskinesia, Drug-Induced.
- Adult, Humans, Male, Receptors, Dopamine D2.
Abstract
Sulpiride is a selective D2-receptor antagonist with antipsychotic and antidepressant properties. Although initially thought to be free of extrapyramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported occasionally. We studied a 37-year-old man who developed persistent segmental dystonia within 2 months after starting sulpiride therapy. We could not find any previous reports of sulpiride-induced tardive dystonia.
DOI: 10.1002/mds.870050119
PubMed: 1967484
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