Age at menopause predicts age at onset of Parkinson's disease.
Identifieur interne : 001883 ( Ncbi/Curation ); précédent : 001882; suivant : 001884Age at menopause predicts age at onset of Parkinson's disease.
Auteurs : Paolo Ragonese [Italie] ; Marco D'Amelio ; Graziella Callari ; Giuseppe Salemi ; Letterio Morgante ; Giovanni SavettieriSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.
English descriptors
- KwdEn :
- MESH :
- physiology : Aging, Menopause.
- Adult, Age of Onset, Aged, Aged, 80 and over, Female, Humans, Linear Models, Middle Aged, Parkinson Disease, Pregnancy, Risk Assessment, Risk Factors.
Abstract
We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD.
DOI: 10.1002/mds.21127
PubMed: 17029261
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pubmed:17029261Le document en format XML
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<author><name sortKey="Ragonese, Paolo" sort="Ragonese, Paolo" uniqKey="Ragonese P" first="Paolo" last="Ragonese">Paolo Ragonese</name>
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<author><name sortKey="D Amelio, Marco" sort="D Amelio, Marco" uniqKey="D Amelio M" first="Marco" last="D'Amelio">Marco D'Amelio</name>
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<author><name sortKey="Callari, Graziella" sort="Callari, Graziella" uniqKey="Callari G" first="Graziella" last="Callari">Graziella Callari</name>
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<author><name sortKey="Salemi, Giuseppe" sort="Salemi, Giuseppe" uniqKey="Salemi G" first="Giuseppe" last="Salemi">Giuseppe Salemi</name>
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<author><name sortKey="Salemi, Giuseppe" sort="Salemi, Giuseppe" uniqKey="Salemi G" first="Giuseppe" last="Salemi">Giuseppe Salemi</name>
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<author><name sortKey="Morgante, Letterio" sort="Morgante, Letterio" uniqKey="Morgante L" first="Letterio" last="Morgante">Letterio Morgante</name>
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<term>Aging (physiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Linear Models</term>
<term>Menopause (physiology)</term>
<term>Middle Aged</term>
<term>Parkinson Disease</term>
<term>Pregnancy</term>
<term>Risk Assessment</term>
<term>Risk Factors</term>
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<term>Age of Onset</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Linear Models</term>
<term>Middle Aged</term>
<term>Parkinson Disease</term>
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<front><div type="abstract" xml:lang="en">We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD.</div>
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