MovDisordV3, Ncbi, Merge, bibRecord, 001883

Age at menopause predicts age at onset of Parkinson's disease.

Identifieur interne : 001883 ( Ncbi/Merge ); précédent : 001882; suivant : 001884

Age at menopause predicts age at onset of Parkinson's disease.

Auteurs : Paolo Ragonese [Italie] ; Marco D'Amelio ; Graziella Callari ; Giuseppe Salemi ; Letterio Morgante ; Giovanni Savettieri

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.

RBID : pubmed:17029261

English descriptors

KwdEn :
- Adult, Age of Onset, Aged, Aged, 80 and over, Aging (physiology), Female, Humans, Linear Models, Menopause (physiology), Middle Aged, Parkinson Disease, Pregnancy, Risk Assessment, Risk Factors.
MESH :
- physiology : Aging, Menopause.
- Adult, Age of Onset, Aged, Aged, 80 and over, Female, Humans, Linear Models, Middle Aged, Parkinson Disease, Pregnancy, Risk Assessment, Risk Factors.

Abstract

We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD.

DOI: 10.1002/mds.21127
PubMed: 17029261

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pubmed:17029261

Le document en format XML

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<author><name sortKey="Ragonese, Paolo" sort="Ragonese, Paolo" uniqKey="Ragonese P" first="Paolo" last="Ragonese">Paolo Ragonese</name>
<affiliation wicri:level="1"><nlm:affiliation>Dipartimento di Neuroscienze Cliniche, University of Palermo, Palermo, Italy.</nlm:affiliation>
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<author><name sortKey="D Amelio, Marco" sort="D Amelio, Marco" uniqKey="D Amelio M" first="Marco" last="D'Amelio">Marco D'Amelio</name>
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<author><name sortKey="Salemi, Giuseppe" sort="Salemi, Giuseppe" uniqKey="Salemi G" first="Giuseppe" last="Salemi">Giuseppe Salemi</name>
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<author><name sortKey="Morgante, Letterio" sort="Morgante, Letterio" uniqKey="Morgante L" first="Letterio" last="Morgante">Letterio Morgante</name>
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<author><name sortKey="Savettieri, Giovanni" sort="Savettieri, Giovanni" uniqKey="Savettieri G" first="Giovanni" last="Savettieri">Giovanni Savettieri</name>
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<author><name sortKey="Salemi, Giuseppe" sort="Salemi, Giuseppe" uniqKey="Salemi G" first="Giuseppe" last="Salemi">Giuseppe Salemi</name>
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<term>Aging (physiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Linear Models</term>
<term>Menopause (physiology)</term>
<term>Middle Aged</term>
<term>Parkinson Disease</term>
<term>Pregnancy</term>
<term>Risk Assessment</term>
<term>Risk Factors</term>
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<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Aging</term>
<term>Menopause</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Age of Onset</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Linear Models</term>
<term>Middle Aged</term>
<term>Parkinson Disease</term>
<term>Pregnancy</term>
<term>Risk Assessment</term>
<term>Risk Factors</term>
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<front><div type="abstract" xml:lang="en">We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD.</div>
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<DateCreated><Year>2006</Year>
<Month>12</Month>
<Day>27</Day>
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<DateCompleted><Year>2007</Year>
<Month>02</Month>
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<Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN>
<JournalIssue CitedMedium="Print"><Volume>21</Volume>
<Issue>12</Issue>
<PubDate><Year>2006</Year>
<Month>Dec</Month>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
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<ArticleTitle>Age at menopause predicts age at onset of Parkinson's disease.</ArticleTitle>
<Pagination><MedlinePgn>2211-4</MedlinePgn>
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<Abstract><AbstractText>We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD.</AbstractText>
<CopyrightInformation>Copyright 2006 Movement Disorder Society.</CopyrightInformation>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
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<name sortKey="Savettieri, Giovanni" sort="Savettieri, Giovanni" uniqKey="Savettieri G" first="Giovanni" last="Savettieri">Giovanni Savettieri</name>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Age at menopause predicts age at onset of Parkinson's disease.

Age at menopause predicts age at onset of Parkinson's disease.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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Pour générer des pages wiki