Alzheimer's disease presenting as corticobasal syndrome.
Identifieur interne : 001844 ( Ncbi/Curation ); précédent : 001843; suivant : 001845Alzheimer's disease presenting as corticobasal syndrome.
Auteurs : Pratap Chand [États-Unis] ; Jordan Grafman ; Dennis Dickson ; Keisuke Ishizawa ; Irene LitvanSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.
English descriptors
- KwdEn :
- Alzheimer Disease (complications), Alzheimer Disease (metabolism), Alzheimer Disease (pathology), Basal Ganglia Diseases (etiology), Basal Ganglia Diseases (pathology), Cerebral Amyloid Angiopathy (pathology), Functional Laterality, Hand (physiopathology), Humans, Male, Middle Aged, Myoclonus (etiology), Neurodegenerative Diseases (etiology), Neurodegenerative Diseases (metabolism), Neuropsychological Tests, Plaque, Amyloid (pathology), Supranuclear Palsy, Progressive (etiology), tau Proteins (metabolism).
- MESH :
- chemical , metabolism : tau Proteins.
- complications : Alzheimer Disease.
- etiology : Basal Ganglia Diseases, Myoclonus, Neurodegenerative Diseases, Supranuclear Palsy, Progressive.
- metabolism : Alzheimer Disease, Neurodegenerative Diseases.
- pathology : Alzheimer Disease, Basal Ganglia Diseases, Cerebral Amyloid Angiopathy, Plaque, Amyloid.
- physiopathology : Hand.
- Functional Laterality, Humans, Male, Middle Aged, Neuropsychological Tests.
Abstract
A 60-year-old man presented with slowly progressive left hemi-Parkinsonism, left hand apraxia, myoclonus, dystonia, visuospatial disturbances, and alien limb phenomenon, resembling corticobasal syndrome. Eight years later, neuropathology revealed features of Alzheimer's disease, with asymmetrical (right more than left) cortical tau burden with image analysis. The videotaped clinical features, neuropsychological aspects, and neuropathological correlates are presented and discussed.
DOI: 10.1002/mds.21055
PubMed: 16977625
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pubmed:16977625Le document en format XML
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<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA.</nlm:affiliation>
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<wicri:regionArea>Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky 40202</wicri:regionArea>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Basal Ganglia Diseases (etiology)</term>
<term>Basal Ganglia Diseases (pathology)</term>
<term>Cerebral Amyloid Angiopathy (pathology)</term>
<term>Functional Laterality</term>
<term>Hand (physiopathology)</term>
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<term>Neurodegenerative Diseases (metabolism)</term>
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<front><div type="abstract" xml:lang="en">A 60-year-old man presented with slowly progressive left hemi-Parkinsonism, left hand apraxia, myoclonus, dystonia, visuospatial disturbances, and alien limb phenomenon, resembling corticobasal syndrome. Eight years later, neuropathology revealed features of Alzheimer's disease, with asymmetrical (right more than left) cortical tau burden with image analysis. The videotaped clinical features, neuropsychological aspects, and neuropathological correlates are presented and discussed.</div>
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