Movement Disorders (revue)

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Alzheimer's disease presenting as corticobasal syndrome.

Identifieur interne : 001844 ( Ncbi/Curation ); précédent : 001843; suivant : 001845

Alzheimer's disease presenting as corticobasal syndrome.

Auteurs : Pratap Chand [États-Unis] ; Jordan Grafman ; Dennis Dickson ; Keisuke Ishizawa ; Irene Litvan

Source :

RBID : pubmed:16977625

English descriptors

Abstract

A 60-year-old man presented with slowly progressive left hemi-Parkinsonism, left hand apraxia, myoclonus, dystonia, visuospatial disturbances, and alien limb phenomenon, resembling corticobasal syndrome. Eight years later, neuropathology revealed features of Alzheimer's disease, with asymmetrical (right more than left) cortical tau burden with image analysis. The videotaped clinical features, neuropsychological aspects, and neuropathological correlates are presented and discussed.

DOI: 10.1002/mds.21055
PubMed: 16977625

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Le document en format XML

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<name sortKey="Chand, Pratap" sort="Chand, Pratap" uniqKey="Chand P" first="Pratap" last="Chand">Pratap Chand</name>
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<nlm:affiliation>Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky 40202</wicri:regionArea>
<wicri:noRegion>Kentucky 40202</wicri:noRegion>
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<name sortKey="Grafman, Jordan" sort="Grafman, Jordan" uniqKey="Grafman J" first="Jordan" last="Grafman">Jordan Grafman</name>
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<term>Alzheimer Disease (complications)</term>
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<term>Basal Ganglia Diseases (etiology)</term>
<term>Basal Ganglia Diseases (pathology)</term>
<term>Cerebral Amyloid Angiopathy (pathology)</term>
<term>Functional Laterality</term>
<term>Hand (physiopathology)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Myoclonus (etiology)</term>
<term>Neurodegenerative Diseases (etiology)</term>
<term>Neurodegenerative Diseases (metabolism)</term>
<term>Neuropsychological Tests</term>
<term>Plaque, Amyloid (pathology)</term>
<term>Supranuclear Palsy, Progressive (etiology)</term>
<term>tau Proteins (metabolism)</term>
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<term>tau Proteins</term>
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<term>Alzheimer Disease</term>
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<term>Alzheimer Disease</term>
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<div type="abstract" xml:lang="en">A 60-year-old man presented with slowly progressive left hemi-Parkinsonism, left hand apraxia, myoclonus, dystonia, visuospatial disturbances, and alien limb phenomenon, resembling corticobasal syndrome. Eight years later, neuropathology revealed features of Alzheimer's disease, with asymmetrical (right more than left) cortical tau burden with image analysis. The videotaped clinical features, neuropsychological aspects, and neuropathological correlates are presented and discussed.</div>
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