Levodopa-responsive parkinsonism associated with hydrocephalus.
Identifieur interne : 001659 ( Ncbi/Curation ); précédent : 001658; suivant : 001660Levodopa-responsive parkinsonism associated with hydrocephalus.
Auteurs : Mi Jung Kim [Corée du Sud] ; Sun J. Chung ; Young H. Sung ; Myoung C. Lee ; Joo-Hyuk ImSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Antiparkinson Agents, Levodopa.
- complications : Hydrocephalus, Parkinson Disease.
- drug therapy : Parkinson Disease.
- pathology : Brain.
- Female, Humans, Magnetic Resonance Imaging, Middle Aged.
Abstract
We report on a patient who developed acute parkinsonian symptoms following shunt revision for hydrocephalus. Parkinsonism improved dramatically after levodopa therapy. Furthermore, there was no recurrence of Parkinsonism despite discontinuation of levodopa. This observation suggests that Parkinsonism in this patient was caused by reversible dysfunction of the presynaptic nigrostriatal dopaminergic pathway due to hydrocephalus.
DOI: 10.1002/mds.20901
PubMed: 16639728
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