Levodopa-responsive parkinsonism associated with hydrocephalus.
Identifieur interne : 002C75 ( PubMed/Corpus ); précédent : 002C74; suivant : 002C76Levodopa-responsive parkinsonism associated with hydrocephalus.
Auteurs : Mi Jung Kim ; Sun J. Chung ; Young H. Sung ; Myoung C. Lee ; Joo-Hyuk ImSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Antiparkinson Agents, Levodopa.
- complications : Hydrocephalus, Parkinson Disease.
- drug therapy : Parkinson Disease.
- pathology : Brain.
- Female, Humans, Magnetic Resonance Imaging, Middle Aged.
Abstract
We report on a patient who developed acute parkinsonian symptoms following shunt revision for hydrocephalus. Parkinsonism improved dramatically after levodopa therapy. Furthermore, there was no recurrence of Parkinsonism despite discontinuation of levodopa. This observation suggests that Parkinsonism in this patient was caused by reversible dysfunction of the presynaptic nigrostriatal dopaminergic pathway due to hydrocephalus.
DOI: 10.1002/mds.20901
PubMed: 16639728
Links to Exploration step
pubmed:16639728Le document en format XML
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<author><name sortKey="Kim, Mi Jung" sort="Kim, Mi Jung" uniqKey="Kim M" first="Mi Jung" last="Kim">Mi Jung Kim</name>
<affiliation><nlm:affiliation>Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chung, Sun J" sort="Chung, Sun J" uniqKey="Chung S" first="Sun J" last="Chung">Sun J. Chung</name>
</author>
<author><name sortKey="Sung, Young H" sort="Sung, Young H" uniqKey="Sung Y" first="Young H" last="Sung">Young H. Sung</name>
</author>
<author><name sortKey="Lee, Myoung C" sort="Lee, Myoung C" uniqKey="Lee M" first="Myoung C" last="Lee">Myoung C. Lee</name>
</author>
<author><name sortKey="Im, Joo Hyuk" sort="Im, Joo Hyuk" uniqKey="Im J" first="Joo-Hyuk" last="Im">Joo-Hyuk Im</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Levodopa-responsive parkinsonism associated with hydrocephalus.</title>
<author><name sortKey="Kim, Mi Jung" sort="Kim, Mi Jung" uniqKey="Kim M" first="Mi Jung" last="Kim">Mi Jung Kim</name>
<affiliation><nlm:affiliation>Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.</nlm:affiliation>
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<author><name sortKey="Chung, Sun J" sort="Chung, Sun J" uniqKey="Chung S" first="Sun J" last="Chung">Sun J. Chung</name>
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<author><name sortKey="Sung, Young H" sort="Sung, Young H" uniqKey="Sung Y" first="Young H" last="Sung">Young H. Sung</name>
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<author><name sortKey="Lee, Myoung C" sort="Lee, Myoung C" uniqKey="Lee M" first="Myoung C" last="Lee">Myoung C. Lee</name>
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<author><name sortKey="Im, Joo Hyuk" sort="Im, Joo Hyuk" uniqKey="Im J" first="Joo-Hyuk" last="Im">Joo-Hyuk Im</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2006" type="published">2006</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiparkinson Agents (therapeutic use)</term>
<term>Brain (pathology)</term>
<term>Female</term>
<term>Humans</term>
<term>Hydrocephalus (complications)</term>
<term>Levodopa (therapeutic use)</term>
<term>Magnetic Resonance Imaging</term>
<term>Middle Aged</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (drug therapy)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term>
<term>Levodopa</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Hydrocephalus</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Female</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Middle Aged</term>
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<front><div type="abstract" xml:lang="en">We report on a patient who developed acute parkinsonian symptoms following shunt revision for hydrocephalus. Parkinsonism improved dramatically after levodopa therapy. Furthermore, there was no recurrence of Parkinsonism despite discontinuation of levodopa. This observation suggests that Parkinsonism in this patient was caused by reversible dysfunction of the presynaptic nigrostriatal dopaminergic pathway due to hydrocephalus.</div>
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<DateRevised><Year>2013</Year>
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<Month>Aug</Month>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
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<ArticleTitle>Levodopa-responsive parkinsonism associated with hydrocephalus.</ArticleTitle>
<Pagination><MedlinePgn>1279-81</MedlinePgn>
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<Abstract><AbstractText>We report on a patient who developed acute parkinsonian symptoms following shunt revision for hydrocephalus. Parkinsonism improved dramatically after levodopa therapy. Furthermore, there was no recurrence of Parkinsonism despite discontinuation of levodopa. This observation suggests that Parkinsonism in this patient was caused by reversible dysfunction of the presynaptic nigrostriatal dopaminergic pathway due to hydrocephalus.</AbstractText>
<CopyrightInformation>(c) 2006 Movement Disorder Society</CopyrightInformation>
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<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kim</LastName>
<ForeName>Mi Jung</ForeName>
<Initials>MJ</Initials>
<AffiliationInfo><Affiliation>Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.</Affiliation>
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<MedlineJournalInfo><Country>United States</Country>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007980">Levodopa</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName>
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