Did Gustav Mahler have Sydenham's chorea?
Identifieur interne : 001550 ( Ncbi/Curation ); précédent : 001549; suivant : 001551Did Gustav Mahler have Sydenham's chorea?
Auteurs : Francisco Cardoso [Brésil] ; Andrew J. LeesSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.
Descripteurs français
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- Chorea (etiology), Chorea (history), Chorea (physiopathology), Dyskinesia, Drug-Induced (etiology), Endocarditis, Subacute Bacterial (etiology), Endocarditis, Subacute Bacterial (physiopathology), Germany, Heart Valve Diseases (microbiology), Heart Valve Diseases (physiopathology), History, 19th Century, History, 20th Century, Music (history), Obsessive-Compulsive Disorder (diagnosis), Obsessive-Compulsive Disorder (etiology), Rheumatic Fever (complications).
- MESH :
- geographic : Germany.
- complications : Rheumatic Fever.
- diagnosis : Obsessive-Compulsive Disorder.
- etiology : Chorea, Dyskinesia, Drug-Induced, Endocarditis, Subacute Bacterial, Obsessive-Compulsive Disorder.
- history : Chorea, Music.
- microbiology : Heart Valve Diseases.
- physiopathology : Chorea, Endocarditis, Subacute Bacterial, Heart Valve Diseases.
- History, 19th Century, History, 20th Century.
Abstract
Sydenham's chorea (SC), a major manifestation of acute rheumatic fever (RF), is characterized by chorea and other motor and non-motor features. Among the latter are behavioral symptoms, including obsessive-compulsive disorder. Although SC is typically a self-limited condition, up to 50% of patients may evolve with persistent chorea. There is evidence that Gustav Mahler had a movement disorder, but its nature remains undetermined. There are witnesses describing him as having facial dyskinesia and a gait disorder consistent with chorea. His conducting performance was notorious for obsessive attention to details of the staging and musical production. Mahler was diagnosed with a valvulopathy in 1907 and died of subacute bacterial endocarditis in 1911. It is possible that the composer suffered from RF in childhood with carditis and SC, which may left him with valvulopathy, obsessive-compulsive disorder, and persistent chorea.
DOI: 10.1002/mds.20788
PubMed: 16437586
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<author><name sortKey="Cardoso, Francisco" sort="Cardoso, Francisco" uniqKey="Cardoso F" first="Francisco" last="Cardoso">Francisco Cardoso</name>
<affiliation wicri:level="4"><nlm:affiliation>Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. cardosofe@terra.com.br</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais</wicri:regionArea>
<placeName><region type="state">Minas Gerais</region>
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<orgName type="university">Université fédérale du Minas Gerais</orgName>
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<author><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J" last="Lees">Andrew J. Lees</name>
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<author><name sortKey="Cardoso, Francisco" sort="Cardoso, Francisco" uniqKey="Cardoso F" first="Francisco" last="Cardoso">Francisco Cardoso</name>
<affiliation wicri:level="4"><nlm:affiliation>Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. cardosofe@terra.com.br</nlm:affiliation>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<imprint><date when="2006" type="published">2006</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chorea (etiology)</term>
<term>Chorea (history)</term>
<term>Chorea (physiopathology)</term>
<term>Dyskinesia, Drug-Induced (etiology)</term>
<term>Endocarditis, Subacute Bacterial (etiology)</term>
<term>Endocarditis, Subacute Bacterial (physiopathology)</term>
<term>Germany</term>
<term>Heart Valve Diseases (microbiology)</term>
<term>Heart Valve Diseases (physiopathology)</term>
<term>History, 19th Century</term>
<term>History, 20th Century</term>
<term>Music (history)</term>
<term>Obsessive-Compulsive Disorder (diagnosis)</term>
<term>Obsessive-Compulsive Disorder (etiology)</term>
<term>Rheumatic Fever (complications)</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Germany</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Rheumatic Fever</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Obsessive-Compulsive Disorder</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Chorea</term>
<term>Dyskinesia, Drug-Induced</term>
<term>Endocarditis, Subacute Bacterial</term>
<term>Obsessive-Compulsive Disorder</term>
</keywords>
<keywords scheme="MESH" qualifier="history" xml:lang="en"><term>Chorea</term>
<term>Music</term>
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<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Heart Valve Diseases</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Chorea</term>
<term>Endocarditis, Subacute Bacterial</term>
<term>Heart Valve Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>History, 19th Century</term>
<term>History, 20th Century</term>
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<front><div type="abstract" xml:lang="en">Sydenham's chorea (SC), a major manifestation of acute rheumatic fever (RF), is characterized by chorea and other motor and non-motor features. Among the latter are behavioral symptoms, including obsessive-compulsive disorder. Although SC is typically a self-limited condition, up to 50% of patients may evolve with persistent chorea. There is evidence that Gustav Mahler had a movement disorder, but its nature remains undetermined. There are witnesses describing him as having facial dyskinesia and a gait disorder consistent with chorea. His conducting performance was notorious for obsessive attention to details of the staging and musical production. Mahler was diagnosed with a valvulopathy in 1907 and died of subacute bacterial endocarditis in 1911. It is possible that the composer suffered from RF in childhood with carditis and SC, which may left him with valvulopathy, obsessive-compulsive disorder, and persistent chorea.</div>
</front>
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