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Long-term botulinum toxin treatment increases employment rate in patients with cervical dystonia.

Identifieur interne : 001412 ( Ncbi/Curation ); précédent : 001411; suivant : 001413

Long-term botulinum toxin treatment increases employment rate in patients with cervical dystonia.

Auteurs : Inger Marie Skogseid [Norvège] ; Jo R Islien ; Bj Rgulf Claussen ; Emilia Kerty

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2005.

RBID : pubmed:16114026

English descriptors

KwdEn :
- Adult, Aged, Anti-Dyskinesia Agents (therapeutic use), Botulinum Toxins (therapeutic use), Chi-Square Distribution, Demography, Employment, Female, Humans, Longitudinal Studies, Male, Middle Aged, Predictive Value of Tests, Time Factors, Torticollis (drug therapy), Torticollis (psychology).
MESH :
- chemical , therapeutic use : Anti-Dyskinesia Agents, Botulinum Toxins.
- drug therapy : Torticollis.
- psychology : Torticollis.
- Adult, Aged, Chi-Square Distribution, Demography, Employment, Female, Humans, Longitudinal Studies, Male, Middle Aged, Predictive Value of Tests, Time Factors.

Abstract

We examined the impact of cervical dystonia (CD) and long-term botulinum toxin (BTX) treatment on employment status. Data on employment status at onset of CD, at initiation of BTX treatment, and at evaluation of long-term treatment were obtained from 62 CD patients aged 31-66 years (median, 53 years; 61% females) who had been treated for a median of 5 years (range, 1.5-10 years). The employment rate fell from 84% at the onset of CD to 47% before initiation of BTX treatment. With long-term BTX treatment, 72% of those who worked at the initiation of treatment stayed employed, and 67% of those on sick leave returned to work. A younger age and a higher level of education increased the probability of being employed and avoiding disability benefits. Among those who were younger than 55 years at evaluation of BTX treatment (n = 40), the employment rate increased from 47% to 65% with treatment, and among the male patients, it reached the level of the general population (86%). About half of the 34% who received disability benefits did so already before the BTX treatment was initiated.

DOI: 10.1002/mds.20670
PubMed: 16114026

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Le document en format XML

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<author><name sortKey="Skogseid, Inger Marie" sort="Skogseid, Inger Marie" uniqKey="Skogseid I" first="Inger Marie" last="Skogseid">Inger Marie Skogseid</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Oslo, Department of Neurology, Rikshospitalet University Hospital, Oslo, Norway. i.m.skogseid@klinmed.uio.no</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>University of Oslo, Department of Neurology, Rikshospitalet University Hospital, Oslo</wicri:regionArea>
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<author><name sortKey="R Islien, Jo" sort="R Islien, Jo" uniqKey="R Islien J" first="Jo" last="R Islien">Jo R Islien</name>
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<author><name sortKey="Claussen, Bj Rgulf" sort="Claussen, Bj Rgulf" uniqKey="Claussen B" first="Bj Rgulf" last="Claussen">Bj Rgulf Claussen</name>
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<author><name sortKey="Kerty, Emilia" sort="Kerty, Emilia" uniqKey="Kerty E" first="Emilia" last="Kerty">Emilia Kerty</name>
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<affiliation wicri:level="1"><nlm:affiliation>University of Oslo, Department of Neurology, Rikshospitalet University Hospital, Oslo, Norway. i.m.skogseid@klinmed.uio.no</nlm:affiliation>
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<author><name sortKey="Claussen, Bj Rgulf" sort="Claussen, Bj Rgulf" uniqKey="Claussen B" first="Bj Rgulf" last="Claussen">Bj Rgulf Claussen</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Chi-Square Distribution</term>
<term>Demography</term>
<term>Employment</term>
<term>Female</term>
<term>Humans</term>
<term>Longitudinal Studies</term>
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<term>Middle Aged</term>
<term>Predictive Value of Tests</term>
<term>Time Factors</term>
<term>Torticollis (drug therapy)</term>
<term>Torticollis (psychology)</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Dyskinesia Agents</term>
<term>Botulinum Toxins</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Torticollis</term>
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<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Torticollis</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Chi-Square Distribution</term>
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<term>Female</term>
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<front><div type="abstract" xml:lang="en">We examined the impact of cervical dystonia (CD) and long-term botulinum toxin (BTX) treatment on employment status. Data on employment status at onset of CD, at initiation of BTX treatment, and at evaluation of long-term treatment were obtained from 62 CD patients aged 31-66 years (median, 53 years; 61% females) who had been treated for a median of 5 years (range, 1.5-10 years). The employment rate fell from 84% at the onset of CD to 47% before initiation of BTX treatment. With long-term BTX treatment, 72% of those who worked at the initiation of treatment stayed employed, and 67% of those on sick leave returned to work. A younger age and a higher level of education increased the probability of being employed and avoiding disability benefits. Among those who were younger than 55 years at evaluation of BTX treatment (n = 40), the employment rate increased from 47% to 65% with treatment, and among the male patients, it reached the level of the general population (86%). About half of the 34% who received disability benefits did so already before the BTX treatment was initiated.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Long-term botulinum toxin treatment increases employment rate in patients with cervical dystonia.

Long-term botulinum toxin treatment increases employment rate in patients with cervical dystonia.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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Pour générer des pages wiki