Long-term botulinum toxin treatment increases employment rate in patients with cervical dystonia.
Identifieur interne : 002F00 ( PubMed/Curation ); précédent : 002E99; suivant : 002F01Long-term botulinum toxin treatment increases employment rate in patients with cervical dystonia.
Auteurs : Inger Marie Skogseid [Norvège] ; Jo R Islien ; Bj Rgulf Claussen ; Emilia KertySource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2005.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Anti-Dyskinesia Agents, Botulinum Toxins.
- drug therapy : Torticollis.
- psychology : Torticollis.
- Adult, Aged, Chi-Square Distribution, Demography, Employment, Female, Humans, Longitudinal Studies, Male, Middle Aged, Predictive Value of Tests, Time Factors.
Abstract
We examined the impact of cervical dystonia (CD) and long-term botulinum toxin (BTX) treatment on employment status. Data on employment status at onset of CD, at initiation of BTX treatment, and at evaluation of long-term treatment were obtained from 62 CD patients aged 31-66 years (median, 53 years; 61% females) who had been treated for a median of 5 years (range, 1.5-10 years). The employment rate fell from 84% at the onset of CD to 47% before initiation of BTX treatment. With long-term BTX treatment, 72% of those who worked at the initiation of treatment stayed employed, and 67% of those on sick leave returned to work. A younger age and a higher level of education increased the probability of being employed and avoiding disability benefits. Among those who were younger than 55 years at evaluation of BTX treatment (n = 40), the employment rate increased from 47% to 65% with treatment, and among the male patients, it reached the level of the general population (86%). About half of the 34% who received disability benefits did so already before the BTX treatment was initiated.
DOI: 10.1002/mds.20670
PubMed: 16114026
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<wicri:regionArea>University of Oslo, Department of Neurology, Rikshospitalet University Hospital, Oslo</wicri:regionArea>
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<author><name sortKey="R Islien, Jo" sort="R Islien, Jo" uniqKey="R Islien J" first="Jo" last="R Islien">Jo R Islien</name>
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<author><name sortKey="Claussen, Bj Rgulf" sort="Claussen, Bj Rgulf" uniqKey="Claussen B" first="Bj Rgulf" last="Claussen">Bj Rgulf Claussen</name>
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<front><div type="abstract" xml:lang="en">We examined the impact of cervical dystonia (CD) and long-term botulinum toxin (BTX) treatment on employment status. Data on employment status at onset of CD, at initiation of BTX treatment, and at evaluation of long-term treatment were obtained from 62 CD patients aged 31-66 years (median, 53 years; 61% females) who had been treated for a median of 5 years (range, 1.5-10 years). The employment rate fell from 84% at the onset of CD to 47% before initiation of BTX treatment. With long-term BTX treatment, 72% of those who worked at the initiation of treatment stayed employed, and 67% of those on sick leave returned to work. A younger age and a higher level of education increased the probability of being employed and avoiding disability benefits. Among those who were younger than 55 years at evaluation of BTX treatment (n = 40), the employment rate increased from 47% to 65% with treatment, and among the male patients, it reached the level of the general population (86%). About half of the 34% who received disability benefits did so already before the BTX treatment was initiated.</div>
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<Abstract><AbstractText>We examined the impact of cervical dystonia (CD) and long-term botulinum toxin (BTX) treatment on employment status. Data on employment status at onset of CD, at initiation of BTX treatment, and at evaluation of long-term treatment were obtained from 62 CD patients aged 31-66 years (median, 53 years; 61% females) who had been treated for a median of 5 years (range, 1.5-10 years). The employment rate fell from 84% at the onset of CD to 47% before initiation of BTX treatment. With long-term BTX treatment, 72% of those who worked at the initiation of treatment stayed employed, and 67% of those on sick leave returned to work. A younger age and a higher level of education increased the probability of being employed and avoiding disability benefits. Among those who were younger than 55 years at evaluation of BTX treatment (n = 40), the employment rate increased from 47% to 65% with treatment, and among the male patients, it reached the level of the general population (86%). About half of the 34% who received disability benefits did so already before the BTX treatment was initiated.</AbstractText>
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