Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease.
Identifieur interne : 001C47 ( Ncbi/Checkpoint ); précédent : 001C46; suivant : 001C48Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease.
Auteurs : Ali Samii [États-Unis] ; Valerie E. Kelly ; Jefferson C. Slimp ; Anne Shumway-Cook ; Robert GoodkinSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2007.
English descriptors
- KwdEn :
- Activities of Daily Living, Adult, Aged, Disability Evaluation, Electric Stimulation (methods), Electric Stimulation Therapy (methods), Electrodes, Implanted, Female, Functional Laterality, Humans, Male, Middle Aged, Parkinson Disease (pathology), Parkinson Disease (surgery), Severity of Illness Index, Subthalamic Nucleus (physiopathology).
- MESH :
- methods : Electric Stimulation, Electric Stimulation Therapy.
- pathology : Parkinson Disease.
- physiopathology : Subthalamic Nucleus.
- surgery : Parkinson Disease.
- Activities of Daily Living, Adult, Aged, Disability Evaluation, Electrodes, Implanted, Female, Functional Laterality, Humans, Male, Middle Aged, Severity of Illness Index.
Abstract
In 17 consecutive patients with Parkinson disease (PD), bilateral subthalamic nucleus (STN) stimulators were implanted during staged surgeries. The Unified Parkinson Disease Rating Scale (UPDRS) and the Dyskinesia Disability Scale were completed both off and on medication prior to any surgery and also OFF and ON stimulation after each surgery. On-medication UPDRS activities of daily living (ADL) and motor examination scores changed little with unilateral or bilateral stimulation. Off-medication UPDRS motor examination scores improved to similar degrees after each staged STN electrode implantation. Most of the improvements in off-medication ADL scores, dyskinesia scores, complications of therapy, and medication dose reduction occurred after unilateral STN stimulation with smaller improvements after the second operation.
DOI: 10.1002/mds.21554
PubMed: 17523194
Affiliations:
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Kelly</name></author><author><name sortKey="Slimp, Jefferson C" sort="Slimp, Jefferson C" uniqKey="Slimp J" first="Jefferson C" last="Slimp">Jefferson C. Slimp</name></author><author><name sortKey="Shumway Cook, Anne" sort="Shumway Cook, Anne" uniqKey="Shumway Cook A" first="Anne" last="Shumway-Cook">Anne Shumway-Cook</name></author><author><name sortKey="Goodkin, Robert" sort="Goodkin, Robert" uniqKey="Goodkin R" first="Robert" last="Goodkin">Robert Goodkin</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="doi">10.1002/mds.21554</idno><idno type="RBID">pubmed:17523194</idno><idno type="pmid">17523194</idno><idno type="wicri:Area/PubMed/Corpus">002692</idno><idno type="wicri:Area/PubMed/Curation">002692</idno><idno type="wicri:Area/PubMed/Checkpoint">002543</idno><idno type="wicri:Area/Ncbi/Merge">001C47</idno><idno type="wicri:Area/Ncbi/Curation">001C47</idno><idno type="wicri:Area/Ncbi/Checkpoint">001C47</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease.</title><author><name sortKey="Samii, Ali" sort="Samii, Ali" uniqKey="Samii A" first="Ali" last="Samii">Ali Samii</name><affiliation wicri:level="4"><nlm:affiliation>Department of Neurology, University of Washington, Seattle, Washington, USA. asamii@u.washington.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Kelly, Valerie E" sort="Kelly, Valerie E" uniqKey="Kelly V" first="Valerie E" last="Kelly">Valerie E. Kelly</name></author><author><name sortKey="Slimp, Jefferson C" sort="Slimp, Jefferson C" uniqKey="Slimp J" first="Jefferson C" last="Slimp">Jefferson C. Slimp</name></author><author><name sortKey="Shumway Cook, Anne" sort="Shumway Cook, Anne" uniqKey="Shumway Cook A" first="Anne" last="Shumway-Cook">Anne Shumway-Cook</name></author><author><name sortKey="Goodkin, Robert" sort="Goodkin, Robert" uniqKey="Goodkin R" first="Robert" last="Goodkin">Robert Goodkin</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Activities of Daily Living</term><term>Adult</term><term>Aged</term><term>Disability Evaluation</term><term>Electric Stimulation (methods)</term><term>Electric Stimulation Therapy (methods)</term><term>Electrodes, Implanted</term><term>Female</term><term>Functional Laterality</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (pathology)</term><term>Parkinson Disease (surgery)</term><term>Severity of Illness Index</term><term>Subthalamic Nucleus (physiopathology)</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Electric Stimulation</term><term>Electric Stimulation Therapy</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Activities of Daily Living</term><term>Adult</term><term>Aged</term><term>Disability Evaluation</term><term>Electrodes, Implanted</term><term>Female</term><term>Functional Laterality</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Severity of Illness Index</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In 17 consecutive patients with Parkinson disease (PD), bilateral subthalamic nucleus (STN) stimulators were implanted during staged surgeries. The Unified Parkinson Disease Rating Scale (UPDRS) and the Dyskinesia Disability Scale were completed both off and on medication prior to any surgery and also OFF and ON stimulation after each surgery. On-medication UPDRS activities of daily living (ADL) and motor examination scores changed little with unilateral or bilateral stimulation. Off-medication UPDRS motor examination scores improved to similar degrees after each staged STN electrode implantation. Most of the improvements in off-medication ADL scores, dyskinesia scores, complications of therapy, and medication dose reduction occurred after unilateral STN stimulation with smaller improvements after the second operation.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Washington (État)</li></region><settlement><li>Seattle</li></settlement><orgName><li>Université de Washington</li></orgName></list><tree><noCountry><name sortKey="Goodkin, Robert" sort="Goodkin, Robert" uniqKey="Goodkin R" first="Robert" last="Goodkin">Robert Goodkin</name><name sortKey="Kelly, Valerie E" sort="Kelly, Valerie E" uniqKey="Kelly V" first="Valerie E" last="Kelly">Valerie E. Kelly</name><name sortKey="Shumway Cook, Anne" sort="Shumway Cook, Anne" uniqKey="Shumway Cook A" first="Anne" last="Shumway-Cook">Anne Shumway-Cook</name><name sortKey="Slimp, Jefferson C" sort="Slimp, Jefferson C" uniqKey="Slimp J" first="Jefferson C" last="Slimp">Jefferson C. Slimp</name></noCountry><country name="États-Unis"><region name="Washington (État)"><name sortKey="Samii, Ali" sort="Samii, Ali" uniqKey="Samii A" first="Ali" last="Samii">Ali Samii</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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