MovDisordV3, Ncbi, Checkpoint, bibRecord, 001986

Health-related quality of life in sporadic adult-onset ataxia.

Identifieur interne : 001986 ( Ncbi/Checkpoint ); précédent : 001985; suivant : 001987

Health-related quality of life in sporadic adult-onset ataxia.

Auteurs : Michael Abele [Allemagne] ; Thomas Klockgether

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2007.

RBID : pubmed:17149704

English descriptors

KwdEn :
- Adult, Aged, Ataxia (physiopathology), Ataxia (psychology), Depression (etiology), Disability Evaluation, Female, Health Status, Humans, Male, Middle Aged, Quality of Life, Questionnaires, Sickness Impact Profile.
MESH :
- etiology : Depression.
- physiopathology : Ataxia.
- psychology : Ataxia.
- Adult, Aged, Disability Evaluation, Female, Health Status, Humans, Male, Middle Aged, Quality of Life, Questionnaires, Sickness Impact Profile.

Abstract

Despite progressive disability in sporadic adult-onset ataxia (SAOA), little is known about patients' assessment of their ataxic disorder and its impact on health-related quality of life (Hr-QoL). This study investigated Hr-QoL by means of the following self-administered scales: Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Beck Depression Inventory (BDI), and the Medical Outcome Study Short Form (SF-36). Twenty-two unselected ataxia patients were included. Sleep-related complaints were found in 9 (41%) of 22 and symptoms of depression in 6 (38%) of 16 patients. Compared to a large german control group, SAOA patients had lower scores in all SF-36 dimensions except for bodily pain. The greatest impairment was found in the domain physical functioning, followed by the domains social functioning and role limitations (emotional problems). There was a significant negative correlation of all nonmotor SF-36 dimensions with the BDI score. Walking aid dependency was significantly correlated with poorer health status perception in several motor and nonmotor domains. In addition, impaired sleep quality was correlated with an impaired general health perception and with bodily pain. The study demonstrates a great impact of SAOA on Hr-QoL. Adequate treatment of depression, motor disability, and impaired sleep quality is essential to improve Hr-QoL in ataxic patients.

DOI: 10.1002/mds.21265
PubMed: 17149704

Affiliations:

Allemagne

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pubmed:17149704

Le document en format XML

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<author><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University of Bonn, Germany. michael.abele@uni-bonn.de</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University of Bonn</wicri:regionArea>
<wicri:noRegion>University of Bonn</wicri:noRegion>
<wicri:noRegion>University of Bonn</wicri:noRegion>
<wicri:noRegion>University of Bonn</wicri:noRegion>
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<author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Health-related quality of life in sporadic adult-onset ataxia.</title>
<author><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name>
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<author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Aged</term>
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<term>Ataxia (psychology)</term>
<term>Depression (etiology)</term>
<term>Disability Evaluation</term>
<term>Female</term>
<term>Health Status</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Quality of Life</term>
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<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Ataxia</term>
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<term>Aged</term>
<term>Disability Evaluation</term>
<term>Female</term>
<term>Health Status</term>
<term>Humans</term>
<term>Male</term>
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<front><div type="abstract" xml:lang="en">Despite progressive disability in sporadic adult-onset ataxia (SAOA), little is known about patients' assessment of their ataxic disorder and its impact on health-related quality of life (Hr-QoL). This study investigated Hr-QoL by means of the following self-administered scales: Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Beck Depression Inventory (BDI), and the Medical Outcome Study Short Form (SF-36). Twenty-two unselected ataxia patients were included. Sleep-related complaints were found in 9 (41%) of 22 and symptoms of depression in 6 (38%) of 16 patients. Compared to a large german control group, SAOA patients had lower scores in all SF-36 dimensions except for bodily pain. The greatest impairment was found in the domain physical functioning, followed by the domains social functioning and role limitations (emotional problems). There was a significant negative correlation of all nonmotor SF-36 dimensions with the BDI score. Walking aid dependency was significantly correlated with poorer health status perception in several motor and nonmotor domains. In addition, impaired sleep quality was correlated with an impaired general health perception and with bodily pain. The study demonstrates a great impact of SAOA on Hr-QoL. Adequate treatment of depression, motor disability, and impaired sleep quality is essential to improve Hr-QoL in ataxic patients.</div>
</front>
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<affiliations><list><country><li>Allemagne</li>
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<tree><noCountry><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
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<country name="Allemagne"><noRegion><name sortKey="Abele, Michael" sort="Abele, Michael" uniqKey="Abele M" first="Michael" last="Abele">Michael Abele</name>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Health-related quality of life in sporadic adult-onset ataxia.

Health-related quality of life in sporadic adult-onset ataxia.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki